Boston Medical Center

This study tests whether a smartphone app with a friendly virtual coach can help people stick with their buprenorphine treatment for opioid use disorder. Researchers will enroll 100 adults who recently started buprenorphine at Boston Medical Center. Participants use the app for d…

This study tests if gabapentin, a medication for nerve pain, can help people with HIV who drink heavily achieve undetectable viral loads. About 220 participants will receive either gabapentin or a placebo for 3 months, along with alcohol counseling. The goal is to see if the drug…

This study looks at different methods to help people with high blood pressure get it under control. It involves nearly 17,000 adults from nine community health centers in Boston. The goal is to find which approaches work best for patients, especially those from diverse background…

This study tests whether automated insulin pumps (hybrid closed loop systems) can improve blood sugar control in underserved adults with type 1 diabetes, who often have worse outcomes. About 140 participants will be randomly assigned to use one of three FDA-approved pumps or stan…

This study tests a new way to help people with uncontrolled type 2 diabetes who also have unmet social needs, like food or housing. The program uses a tool in the medical record to identify these needs and connects patients with community health workers and local organizations. A…

This study looks at whether a special ultrasound placed inside the vein (IVUS) can better detect blockages than the standard X-ray method in people on dialysis. About 50 adults with kidney failure who have dialysis access problems will take part. The goal is to see if IVUS gives …

This study tests a program called CHORUS+ that helps people who inject opioids quickly get HIV prevention medication (PrEP) and addiction treatment (MOUD). Participants receive HIV self-test kits, rapid prescriptions, and 6 months of peer coaching. The goal is to see if this appr…

This study tests a stepped approach to help people with PTSD get effective treatment. Participants start with a digital program and may move to brief therapy if needed. The goal is to improve access, engagement, and symptom relief for 428 adults at Boston Medical Center.

This study tests whether special behavior strategies can help autistic children (ages 3 and up) stay calm and cooperate during needle-related hospital visits. Ten participants will receive personalized interventions based on their unique needs. The goal is to reduce challenging b…

This study tests whether injecting Jeuveau (a botulinum toxin) into the neck muscles can temporarily reduce neck size and create a more feminine, youthful neck shape. About 30 adults who want a more feminine neck appearance will receive the injections. The goal is to see if the t…

This study is testing a new music therapy program to help prevent delirium (sudden confusion) in hospitalized people with brain diseases like Alzheimer's or Parkinson's. About 30 participants will receive up to five personalized music sessions, including live music or playing ins…

This study is creating a large collection of blood, urine, and tissue samples from people with or suspected of having amyloid diseases. The goal is to store these samples and related health data for future laboratory research. No treatments or interventions are given. Up to 10,00…

This study looks at whether simple, non-invasive tests—like measuring pupil reactions, brain waves, or skull vibrations—can help doctors detect dangerous brain swelling earlier in patients with serious brain injuries. The goal is to find better ways to monitor these patients with…

This study tests a short overdose prevention education program for youth ages 13-26 during regular checkups at a primary care clinic. The program teaches teens and young adults about fentanyl risks, safer drug use, and how to use naloxone to reverse an overdose. The goal is to se…

This study looks at whether a program called CenteringParenting, which brings parents and children together for group well-child visits, can improve kindergarten readiness. Researchers will follow 1,200 low-income families from birth to age 3, measuring language skills and parent…

This study looks at whether a careful, step-by-step approach can better predict recovery in people who remain unconscious after a cardiac arrest. Researchers will follow 600 patients in the US, Brazil, and Italy, using multiple tests at specific times to guide decisions. The goal…

This study tests whether sending text message surveys to orthopedic patients can help doctors better understand their recovery. Researchers will enroll up to 3,000 people with specific bone or spine injuries. The goal is to use the survey results to schedule fewer or more clinic …

This study looks at why people with chronic pain or opioid use disorder often have worse pain after spine surgery. Researchers will collect small skin and blood samples to study genes and immune cells linked to pain. The goal is to find biological markers that could lead to bette…

This study looks at whether giving nutritional supplements to patients with critical limb ischemia (a severe form of peripheral artery disease) before and after surgery can improve their nutrition and recovery. About 30 participants will have their blood markers and handgrip stre…

This study tests whether an extra phone call from a nurse after hospital discharge helps patients who speak Spanish, Haitian Creole, Portuguese, Cape Verdean, or Vietnamese understand their care instructions better. About 60 adults will be randomly assigned to receive either stan…

This study aims to uncover the reasons why some efforts to increase vaccination rates work better for certain groups than others. Researchers will interview parents, healthcare workers, and experts to learn what builds vaccine confidence in historically marginalized communities. …

This study tests whether a patient navigator—a guide who helps with appointments, insurance, and paperwork—can speed up infertility care for underserved patients at Boston Medical Center. About 40 people will receive navigator help, and their progress will be compared to similar …