Could a custom vaccine boost the Body's attack on aggressive breast cancer?

NCT ID NCT03387553

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 23 times

Summary

This study tests a vaccine made from a patient's own immune cells, designed to target HER2-positive breast cancer. About 31 people with stage II or III breast cancer will receive the vaccine alongside standard chemotherapy before surgery. The goal is to see if the vaccine can strengthen the immune system's attack on the tumor and improve treatment outcomes.

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Contacts and locations

Locations

  • H. Lee Moffitt Cancer Center and Research Institute

    Tampa, Florida, 33612, United States

Conditions

Explore the condition pages connected to this study.