Mindfulness may ward off Chemo-Brain in breast cancer patients

NCT ID NCT06219434

Completed Symptom relief Sponsor: Thomas Jefferson University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tested whether a mindfulness program could help prevent chemo-brain in women about to start chemotherapy for breast cancer. Fifteen women participated in mindfulness sessions and underwent brain scans and blood tests. The main goal was to see if women would stick with the program, not yet to measure cognitive benefits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: mindfulness meditation (Mindfulness-Based Stress Reduction)
What this could lead to: If it works, this could point toward a simple, drug-free way to reduce chemo-brain symptoms like memory and attention problems.
What could go wrong: This is a very small pilot study with only 15 participants, so results may not apply to everyone. It only measured participation rates, not actual cognitive improvement.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CARCINOMA

Contacts and locations

Locations

Thomas Jefferson University Hopsital

Philadelphia, Pennsylvania, 19107, United States

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