New drug given during breast cancer surgery shows early promise

NCT ID NCT06300411

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial tested a new drug called SRG-514 in 25 people undergoing breast-conserving surgery for breast cancer. The drug was given directly into the area where the tumor was removed. The main goal was to find a safe dose and check for side effects. This is a first step to see if the approach might help control breast cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SRG-514 (a drug containing ketorolac)

What this could lead to

If it works, this could lead to a new treatment given during breast cancer surgery to help control the disease.

What could go wrong

This is a very early, small phase 1 trial focused on safety, not effectiveness. It may not show benefit or could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BREAST CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm ductal breast carcinoma in situ

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Audie Murphy VA

    San Antonio, Texas, 78229, United States

  • Duke Cancer Center

    Durham, North Carolina, 27710, United States

  • Indiana University

    Indianapolis, Indiana, 46202, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Mayo

    Rochester, Minnesota, 55905, United States

  • Memorial Health

    Savannah, Georgia, 31404, United States

  • NYU Langone Health

    New York, New York, 10016, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States