New drug given during breast cancer surgery shows early promise

NCT ID NCT06300411

Completed Disease control Sponsor: SURGE Therapeutics Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial tested a new drug called SRG-514 in 25 people undergoing breast-conserving surgery for breast cancer. The drug was given directly into the area where the tumor was removed. The main goal was to find a safe dose and check for side effects. This is a first step to see if the approach might help control breast cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: SRG-514 (a drug containing ketorolac)
What this could lead to: If it works, this could lead to a new treatment given during breast cancer surgery to help control the disease.
What could go wrong: This is a very early, small phase 1 trial focused on safety, not effectiveness. It may not show benefit or could have side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm ductal breast carcinoma in situ

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER

Contacts and locations

Locations

Audie Murphy VA

San Antonio, Texas, 78229, United States
Duke Cancer Center

Durham, North Carolina, 27710, United States
Indiana University

Indianapolis, Indiana, 46202, United States
MD Anderson Cancer Center

Houston, Texas, 77030, United States
Mayo

Rochester, Minnesota, 55905, United States
Memorial Health

Savannah, Georgia, 31404, United States
NYU Langone Health

New York, New York, 10016, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States

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