New pill shows promise in shrinking Hard-to-Treat breast tumors
NCT ID NCT06253195
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new oral drug called BGB-43395 in 33 Chinese patients with advanced or metastatic HR+/HER2- breast cancer and other solid tumors. The drug blocks a protein (CDK4) that helps cancer cells grow. The goal was to find a safe dose and see if it can shrink tumors when used alone or with other cancer medicines. This is an early-phase trial, so the main focus was safety, not a cure.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Beijing Cancer Hospital
Beijing, Beijing Municipality, 100142, China
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Fudan University Shanghai Cancer Center
Shanghai, Shanghai Municipality, 200000, China
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Fujian Cancer Hospital
Fuzhou, Fujian, 350014, China
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Guangxi Medical University Cancer Hospital
Nanning, Guangxi, 530021, China
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Sun Yat Sen Memorial Hospital, Sun Yat Sen University (South)
Guangzhou, Guangdong, 510245, China
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The First Affiliated Hospital of Nanchang University Branch Donghu
Nanchang, Jiangxi, 330006, China
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The First Hospital of China Medical University
Shenyang, Liaoning, 110001, China