New pain block could replace standard for breast surgery
NCT ID NCT04827030
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether a newer nerve block called ESP works as well as the standard PVB block for pain after breast cancer surgery. 292 women received one of the two blocks before surgery. The main goal was to see how many needed morphine in the first two hours after surgery. The results could help doctors choose a simpler pain control method.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ropivacaine (a numbing medicine)
What this could lead to
If ESP works as well as PVB, it could offer a simpler, safer option for controlling pain after breast surgery.
What could go wrong
This is a completed Phase 4 trial, so results are known. The main risk is that ESP may not be as effective as PVB, leading to more pain or morphine use.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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AP-HP Hôpital Tenon
Paris, 75970, France
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Centre Jean Perrin
Clermont-Ferrand, 63000, France
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Institut Claudius Régaud UICT
Toulouse, 31059, France
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Institut Curie
Saint-Cloud, 92210, France
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Institut de Cancérologie de Lorraine
Vandœuvre-lès-Nancy, 54500, France