Numbing shot before breast surgery may stop long-term pain

NCT ID NCT00370240

Completed Prevention Sponsor: Institut Curie Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether injecting a local anesthetic called ropivacaine into the surgical area could prevent chronic breast pain after breast cancer surgery. Researchers compared the anesthetic to a placebo (salt water) in 260 patients. The goal was to see if fewer people had pain three months after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ropivacaine (a local anesthetic)
What this could lead to: If it works, this could offer a simple way to prevent long-term pain after breast cancer surgery, improving quality of life for many patients.
What could go wrong: This is a completed phase 4 trial, but the results may not apply to all types of breast surgery. The benefit may be small or not clinically meaningful.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST NEOPLASMS PAIN, POSTOPERATIVE

Contacts and locations

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Locations

René Huguenin Center

Saint-Cloud, 92210, France

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