HEALTHY

This study looked at whether people who had COVID-19 more than 5 months ago need only one dose of the Pfizer vaccine, while those who never had it need two doses. The goal was to see if a single shot triggers a strong enough immune response in previously infected adults, includin…

This study tested a new vaccine called V330 in 245 healthy adults aged 18-49 and 60-79 to see if it is safe and how well it triggers the immune system to make antibodies. Participants received either the vaccine or a placebo, and researchers monitored side effects and immune resp…

This study tested a new vaccine called IVX-A12 that aims to protect against two respiratory viruses: RSV and hMPV. It involved 264 healthy adults aged 60 to 85 who received either the vaccine or a placebo. The main goals were to check safety and measure the immune response produc…

This study looked at whether giving a COVID-19 antibody treatment (casirivimab+imdevimab) along with the Moderna vaccine changes how well the vaccine works. About 295 healthy adults took part. The goal was to see if the timing between the antibody treatment and the vaccine matter…

This early-stage study tested a new vaccine formula (V118 Formulation C) in 65 healthy adults to see if it is safe and well-tolerated. Researchers monitored side effects like injection-site reactions and other health events. The study is complete, and results will guide further d…

This early-stage study tested a new oral drug, LY3549492, in 92 Japanese adults—some with type 2 diabetes and some healthy. The main goal was to check safety and side effects, and to see how the drug moves through the body. The study is already completed, and results will help de…

This early-stage study tested whether a combination of two lab-made antibodies (casirivimab and imdevimab) is safe and tolerable in healthy adults. The 45 participants received the drug either as a shot under the skin or through an IV. Researchers monitored for side effects and m…

This study tested whether two specially formulated drinks can help the body get rid of environmental toxins and cancer-causing chemicals. 300 healthy adults, including smokers and non-smokers, participated. Researchers measured toxin breakdown products in urine to see if the drin…

This early-phase study tested a new drug called ABX1100 in 46 people, including healthy volunteers and patients with late-onset Pompe disease. The main goal was to check safety and how the drug moves through the body. Researchers gave single or multiple doses to see if it's safe …

This study tested whether a daily oral pill (DMAU, taken alone or with another hormone) can safely and temporarily lower sperm counts in healthy men to prevent pregnancy. 92 men took the pill or a placebo for 12 weeks. The goal was to see if the pill could suppress sperm producti…

This study tested an investigational drug called ciraparantag to see if it can quickly reverse the effects of the blood thinner rivaroxaban. Sixty-nine healthy adults aged 50 to 75 took rivaroxaban and then received either ciraparantag or a placebo. The main goal was to measure h…

This study tested a drug called ciraparantag to see if it could quickly reverse the effects of the blood thinner apixaban. Sixty healthy adults aged 50 to 75 took part. The goal was to bring blood clotting time back to normal within an hour and keep it stable for several hours.

This study tested a new blood test that measures platelet activity in people taking aspirin or clopidogrel, common drugs to prevent blood clots. Researchers compared this new test to the current standard method in 112 healthy volunteers and severely obese individuals. The goal wa…

This early-stage study tested the safety of a single dose of HB-2121, a potential new diagnostic for celiac disease, in 18 healthy adults and people with celiac disease. Researchers monitored side effects and how the drug moved through the body over 30 days. The goal was not to t…

This study checked how well a new ECG device (Masimo INVSENSOR00057) measures heart rate and detects atrial fibrillation (AFib). It included 365 adults—some healthy and some with AFib. The goal was to see if the device works as well as standard ECG measurements.

This study looked at whether an automated measuring device could improve the accuracy of bladder diaries in women with lower urinary tract symptoms. 187 women (including healthy volunteers) recorded their urine volume using both a traditional paper diary and an automated device o…

This study tested whether atenolol, a widely used beta blocker, can prevent bone loss in the hip and lower back of postmenopausal women. Researchers enrolled 420 women aged 50-75 and compared atenolol to a placebo. The goal is to find a new way to protect bone health using an exi…

This study tested whether gargling with a mouthwash containing cetylpyridinium chloride and zinc can reduce cold and flu symptoms. 150 healthy adults either brushed their teeth alone or brushed and then gargled with the mouthwash twice daily for 90 days. Participants tracked thei…

This study tested a new vaccine (G03-52-01) to see if it is safe and can protect healthy adults from botulinum toxin, a dangerous poison. Over 600 people took part, receiving either the vaccine or a placebo. Researchers measured how well the vaccine triggered protective antibodie…

This study looked at whether a 12-week volleyball-specific warm-up program (called VOLLEY12+) could improve balance and movement control in teenage male volleyball players. Twenty-four players aged 15 to 17 took part, with half doing the special warm-up and half doing their usual…

This study tested whether a higher-than-normal dose of MK-8527, a once-monthly pill to prevent HIV, affects heart rhythm. 42 healthy adults took the study drug, a placebo, or an active control. The main goal was to measure changes in the QT interval, a key heart rhythm marker. Th…

This study looked at whether progressive relaxation exercises—a method of tensing and relaxing muscles—could help first-year nursing students feel less stressed and more resilient before starting clinical practice. Eighty students took part, with half doing eight relaxation sessi…

This study tested a 4-week movement program called Dance-Walk in 117 adults looking to improve their mental health. Participants were randomly assigned to start the program right away or wait. The program combined dance and walking to help people feel more connected to their bodi…

This study tested whether a single session of laser treatment right after gum graft surgery could reduce pain and help the wound heal faster. 36 healthy adults took part. Half got the laser plus standard care, and half got standard care alone. The researchers measured pain, paink…

This study looked at whether a cocoa drink rich in flavanols can prevent the temporary decline in blood vessel function and blood pressure that happens when healthy older adults sit for long periods. Twenty healthy adults aged 65 and older drank either a high-flavanol or low-flav…

This study tested whether a daily multivitamin called Vitals+ can improve health, mood, and thinking skills in healthy adults. Thirty-seven volunteers took either the multivitamin or a placebo for 3 months. Researchers measured changes in cognitive function, mood, and blood nutri…

This study looked at whether taking pine bark extract can help healthy, active people feel less tired and recover faster after hard exercise. Fourteen adults with at least three years of regular exercise took the supplement and did intense cycling. Researchers measured how long t…

This early-stage study tested a new drug called CAN10 in 80 people to see if it is safe and how the body processes it. First, healthy volunteers received a single dose. Then, people with mild to moderate plaque psoriasis received multiple doses. The goal was to check for side eff…

This study looked at whether a nutritional juice blend (containing cherry, cocoa, and other ingredients) can improve sleep in healthy young football players. Fifteen athletes from Aspire Academy took part in a crossover trial where they received both the supplement and a placebo …

This study tested whether a serum with low-dose alpha hydroxy acid (AHA) and polyglutamate acid is safe for people with dark spots left after skin inflammation (post-inflammatory hyperpigmentation). 34 Malaysian adults used the serum for 8 weeks, and researchers checked for side …

This study tested a gymnastics program called SI Kumbang in 66 healthy women aged 60-70. Participants did the exercises three times a week for three months. Researchers measured their heart and lung fitness, muscle strength, balance, and immune markers to see if SI Kumbang was be…

This study tested whether a combination of supplements could improve sleep quality and reduce stress in healthy adults aged 18 to 50. 115 participants took either the supplement or a placebo pill for a period of time. Researchers measured stress levels, mood, and sleep using ques…

This study tested whether a digestive enzyme supplement helps healthy adults digest fats, proteins, and carbs after a heavy meal. 24 participants took either the enzyme or a placebo and then ate a high-macronutrient meal. The goal was to see if the enzymes reduce bloating, gas, a…

This early-stage study tested a new drug called LY3502970 in 72 healthy overweight and obese adults. The main goal was to see if the drug is safe and how the body handles it. Participants were monitored for up to 42 days, and blood tests measured drug levels. The study did not ai…

This study tested if expressive writing—writing about your deepest thoughts and feelings—can reduce anxiety and depression in young adults. 160 participants wrote for 14 days, either to themselves, to a loved one, or just describing their day. The goal was to see which approach w…

This study tested a cosmetic cream (RV2666C) to see if it helps heal skin faster after a laser treatment in 22 adults with darker skin types (IV to VI). Participants applied the cream to a small lasered area on their arm for 18 days. Researchers measured wound healing, redness, a…

This study tested whether applying cold (cryotherapy) works as well as numbing gels or sprays to reduce pain from dental injections in children. One hundred children aged 7 to 10 who needed dental treatment were split into four groups: one got a numbing spray, one got numbing gel…

This study tested a mushroom blend in 40 healthy adults aged 30–60 who sometimes have mild stomach issues like bloating or irregularity. Researchers measured changes in digestion, mood, and gut bacteria over time. The goal was to see if the mushrooms could improve gut health and …

This study tested a new drug called SJP-001 to see if it could ease hangover symptoms after drinking alcohol. 47 healthy adults who drink moderately took either SJP-001, a placebo, or common drugs like fexofenadine and naproxen along with alcohol. Researchers measured how the dru…

This study looked at whether listening to music before and after a heart procedure (coronary angiography) helps patients recover better. 210 adults took part, with half listening to music and half receiving standard care. Researchers measured pain, anxiety, vital signs, comfort, …

This small study tested two simple tools to help night shift nurses feel better: a quiet room to nap or relax, and glasses that block blue/green light. Five nurses from one hospital took part. The goal was to see if these ideas are practical and if they might improve health and r…

This study tested a vibrating device called DigiVibe to see if it reduces pain from injections and fingersticks. Twenty healthy adults who dislike needles received standard shots and shots with the device, then rated their pain. The goal was to find a simple way to ease needle-re…

This study tested a drug called TD-1211 in healthy people and those with constipation caused by opioid painkillers. The goal was to see if it is safe and helps with bowel movements. About 102 adults took part, and they had to stop using other laxatives during the study.

This early-stage study tested a new drug called RAY1225 in 68 healthy and obese adults to see if it is safe and how the body processes it. Researchers measured side effects, weight changes, and waist size. The goal is to gather initial safety data before larger trials can explore…

This study tested an injection called AYP-101 to reduce fat under the chin (double chin) in 252 healthy adults aged 19 to 65. Participants received either the drug or a placebo, and doctors and patients rated the fat reduction. The goal was to see if the injection safely improves…

This study tested an experimental oral medication, NG101, to see if it could reduce gastrointestinal side effects (like nausea and vomiting) caused by GLP-1 agonist injections, such as semaglutide. 120 healthy adults with a BMI between 22 and 35 took either NG101 or a placebo for…

This study tested two sedation drugs, remimazolam and midazolam, in 132 healthy adults undergoing upper gastrointestinal endoscopy. The goal was to see which drug allows for a shorter procedure time and better sedation success. Participants did not know which drug they received. …

This study tested an anti-aging face cream on 44 women aged 45 to 65 with sensitive skin and deep wrinkles. Over 60 days, researchers checked how well the cream was tolerated by the skin and eyes, and measured its ability to smooth wrinkles. The goal was to see if the cream could…

This study looked at whether taking a daily rhodiola rosea supplement for 28 days could help basketball players perform better in simulated games and feel less tired. Forty-eight healthy, professional male basketball players took either the supplement or a placebo. Researchers me…

This study tested a cream made from natural plant extracts, niacinamide, and arbutin for its ability to safely lighten dark spots left after skin inflammation. Twenty-five healthy Malaysian adults used the cream for 20 weeks, and researchers checked their skin at several points. …

This study tested whether taking a probiotic called Weizmannella coagulans BC99 for 12 weeks helps healthy adults (ages 18-35) digest protein better and improve muscle and athletic performance. Researchers measured changes in digestive enzymes, amino acids, body composition, and …

This study looked at whether restricting blood flow during leg weight exercises helps build more muscle strength and size than regular training. Eight healthy adults completed the program, and researchers measured muscle force and body composition. The goal was to learn if this t…

This study looked at how two common drugs, itraconazole and rifampin, change the way the body processes selpercatinib, a cancer treatment. Twenty-four healthy adults took selpercatinib alone and then with each of the other drugs. The goal was to measure drug levels in the blood, …

This study looked at how a high-fat, high-calorie meal changes the way the drug acoramidis is processed in the body. 18 healthy adults took a single dose of acoramidis either with food or on an empty stomach. Researchers measured drug levels in the blood to see if food affects ab…

This study looked at how a high-fat meal and a common stomach-acid drug (omeprazole) change the way the body absorbs and clears selpercatinib. Twenty healthy adults took single doses under different conditions. The goal was to gather safety and drug-level information, not to trea…

This study followed 198 runners in the 2015 Ultra-Trail du Mont-Blanc to see if drinking only when thirsty (versus following a set schedule) helps maintain healthy sodium levels in the blood. The goal was to understand how different hydration strategies affect the body during ext…

This early-stage study tested an inhaled form of the anti-nausea drug granisetron (called AZ-010) in 36 healthy adults. The goal was to check its safety and how the body processes it, comparing different doses and also comparing it to the standard IV form. No treatment was given …

This early-stage study tested a new drug called LY3526318 in 16 healthy adults to see how the body absorbs and gets rid of it. Participants took the drug by mouth once or multiple times, and researchers checked for side effects. The goal was to gather basic safety information, no…

This study looked at whether children as young as 6 months old can have a brain MRI without being sedated. Usually, young kids need medicine to keep them still for the scan. The researchers tried the scan on 23 healthy children to see if it's possible. The goal is to make brain i…

This study looked at how the drug selpercatinib moves through the body in people with different levels of kidney function. It included 37 adults, some healthy and some with kidney problems. The goal was to see how kidney impairment changes drug levels and clearance, helping docto…

This small study tested whether drinking a KETO5 XOGenius beverage every day could improve markers of heart and brain health in 6 healthy adults aged 18-50. Researchers measured blood pressure, cholesterol, artery function, and thinking skills. The goal was to gather early clues,…

This study looked at whether adding mental tasks (like counting or memory games) to standard exercise helps people with COPD improve their thinking and physical abilities. 42 people with COPD and healthy adults took part. The COPD patients did either regular pulmonary rehab or th…

This study looked at how food, different pill versions, and a common heartburn drug (a PPI) change the amount of the experimental drug MK-1084 in the blood. 56 healthy adults each took a single dose of MK-1084 under different conditions. The goal was to learn the best way to take…

This early-stage trial tested the safety and tolerability of an experimental drug called BI 1015550 in 42 healthy men. Participants received either a single dose or multiple doses of the drug. The goal was to see how the body handles the drug and whether it causes side effects, n…

This study looked at how a single dose of selpercatinib changes the amount of rosuvastatin in the blood of 28 healthy adults. The goal was to understand any drug interactions and check safety. Participants were healthy Caucasians with a BMI between 19 and 32. The study lasted abo…

This study looked at how a new drug called MT-8554 changes the way the body processes two common cholesterol-lowering medicines, simvastatin and rosuvastatin. It involved 28 healthy adult men. The goal was to see if taking MT-8554 with these statins affects their levels in the bl…

This study looked at how the antifungal drug fluconazole changes the way the body processes an experimental drug called BI 425809. Fifteen healthy men took BI 425809 alone and then again while also taking fluconazole. The goal was to measure drug levels in the blood, not to treat…

This study looked at how a new medicine called BI 1584862 moves through and leaves the body of 8 healthy men. Participants took the medicine by mouth with a tiny radioactive label, and also received a very small dose directly into a vein with a stable label. Researchers measured …

This study looked at how eating a high-fat or low-fat meal changes the way the body absorbs a new drug called HMPL-523. Eighteen healthy adults took the drug under different eating conditions. The goal was to see if food affects drug levels in the blood, which helps doctors decid…

This study involved 24 healthy adults to compare how well two different pill forms of the drug BI 1015550 are absorbed by the body. It also looked at whether taking the drug with food changes absorption. The goal was to gather information, not to treat any disease.

This trial looked at how eating a meal affects the amount of zongertinib that enters the bloodstream. Sixteen healthy men each took a single dose of the drug once with food and once on an empty stomach. The results will help doctors decide whether to take this medicine with or wi…

This early-stage study tested a new drug called LY3451838 in 53 healthy adults to see if it is safe and how the body processes it. Participants received either a single dose into a vein or just under the skin. The main goal was to track any side effects and measure drug levels in…

This study looked at the gut's own nervous system and its connection to the intestinal barrier in 16 healthy adults. Researchers took colon samples and measured rectal function to understand what's normal. The results will help compare with patients who have conditions like spina…

This study checked if a new balance assessment system works correctly and gives consistent results. Forty healthy young adults completed balance tests on the new system and a standard device, with repeat testing a week later. The goal was to see if the new tool is a valid and rel…

This study tested whether a smartphone app paired with a fitness tracker could help adults aged 60 to 80 become more active and improve their health. Researchers compared the app users to a group that received standard health education. The goal was to see if the app was easy to …

This study tested whether giving iodine supplements to pregnant women in an area with mild iodine deficiency helps their children's brain development. 85 mothers and their children took part. The children's thinking and learning skills were tested at age 2 using the Bayley test.

This study looked at whether a daily high-CBD cannabis extract is safe for healthy young men who play contact sports like football or hockey. 34 athletes took a placebo for 2 weeks, then gradually increased their CBD dose over several weeks. Researchers monitored for side effects…

This study looked at how a new experimental drug (BI 1015550) changes the way the body processes two common lung disease medications (nintedanib and pirfenidone). Fourteen healthy men took the new drug multiple times, then a single dose of each lung drug. Researchers measured dru…

This study looked at how the antifungal drug itraconazole changes the way the body processes a single dose of an experimental drug called BI 706321. Fourteen healthy male volunteers took BI 706321 alone and then again with itraconazole. The goal was to measure drug levels in the …

This early-phase study tested the safety and tolerability of a single dose of IBI3032 in 40 healthy adults. Participants were randomly assigned to receive either the drug or a placebo, and some groups also looked at how food affects the drug. The main goal was to check for side e…

This study looked at whether taking four dietary supplements and making lifestyle changes can affect gene activity and blood markers in healthy adults aged 30-55. Over 12 weeks, 97 participants provided blood, urine, and stool samples to measure changes in gene expression, vitami…

This trial looked at two different versions of the drug nerandomilast and checked if eating food changes how the new version is absorbed. Fifteen healthy adults took single doses in a random order. The goal was to see how the drug moves through the body, not to treat any disease.

This study looked at how azvudine tablets move through the body and whether they are safe in 24 healthy adults and older adults. Participants took a single dose, then after a break took daily doses for a week. The goal was to measure drug levels and check for side effects, not to…

This study looked at how different parts of the brain work together to help us remember events. Healthy young adults received mild magnetic stimulation to certain brain areas while doing memory tasks. The goal was to understand which brain networks are important for memory, not t…

This study looked at how a new drug, BI 1569912, is absorbed, broken down, and removed from the body. Eight healthy men took the drug by mouth with a tiny radioactive marker, and also received a very small dose into a vein. The goal was to measure how much of the drug reaches the…

This study looked at how people with brain tumors (glioblastoma or glioma) or breast cancer perceive their own memory problems, especially remembering to do things in the future. Over 400 participants completed questionnaires about memory, mood, and fatigue. The goal was to under…

This study looked at how a common antibiotic (clarithromycin) changes the amount of a new drug (LY3502970) in the blood of 26 healthy adults. Participants took the new drug alone and then with the antibiotic over about 85 days. The goal was simply to measure drug levels, not to t…

This study looked at how breathing in diesel exhaust affects the heart and blood vessels in healthy adults aged 50-75 who have a specific gene variation (GSTM1 null). Six volunteers breathed in three different levels of diesel exhaust over several weeks. The goal was to understan…

This study looked at how a probiotic called S. boulardii affects the gut's ability to control what passes into the body. Researchers gave the probiotic or a placebo to 56 healthy adults and measured changes in gut barrier markers. The goal was to learn more about gut health, not …

This study looked at whether eating two types of sweet oranges—one rich in certain pigments (Rosy Red Valencia) and one without them (Olinda Valencia)—affects markers of inflammation and oxidative stress in healthy adults. Twenty participants ate one of the two orange varieties d…

This study looked at how a cancer drug called selpercatinib changes the way the body handles repaglinide, a medicine for diabetes. Sixteen healthy adults took part to measure drug levels and safety over 12 days. The results will help doctors adjust doses when these drugs are used…

This study tested how much of the germ-killing ingredient chlorhexidine remains in special bandages after being worn for 7 days. 45 healthy adults wore different types of medicated dressings to see how much of the drug and a related chemical called PCA stayed in the patch. The go…

This study looked at whether APF530, a drug given under the skin, changes the heart's electrical activity (QT interval) in healthy adults. Fifty-six volunteers received APF530, a placebo, and other drugs in random order. The goal was to measure any heart rhythm effects and compar…

This study tested a new drug called ZE63-0302 in 82 healthy adults to see if it is safe and how the body handles it. Participants received either the drug or a placebo by mouth. The goal was to measure side effects and drug levels in the blood, not to treat any disease.

This early-stage study tested the safety and tolerability of MK-1167 in 30 healthy adults. Researchers monitored side effects and how the drug moved through the body. The goal was to gather safety information, not to treat any disease.

This study looked at how a new drug called BI 3000202 affects the way the body processes two other drugs: rosuvastatin (used for cholesterol) and digoxin (used for heart conditions). Fourteen healthy adults took part. The goal was to measure drug levels in the blood to see if BI …

This study looked at how two HIV drugs, doravirine and islatravir, move into breast milk in 12 healthy breastfeeding women. The goal was to measure how much of the drugs get into breast milk and estimate the dose a nursing infant might receive. Results help guide safe use of thes…

This study looked at how a new drug, zongertinib, changes the way other common drugs (dabigatran, rosuvastatin, metformin, and furosemide) are processed in the body. Thirty-two healthy men took zongertinib along with these other drugs, and researchers measured the drug levels in …

This study tested whether drugs that boost serotonin (like some psychedelics) can increase pro-social behaviors—such as empathy, generosity, and cooperation—in healthy adults aged 18-40. Participants completed tasks measuring empathy, moral decisions, and charitable giving after …

This study looked at how imlunestrant enters the blood and leaves the body in women with liver problems compared to healthy women. 27 women took part, and researchers measured drug levels and side effects. The goal was to understand dosing needs, not to treat any disease.

This study looked at whether small molecules called microRNAs from broccoli can be found in the blood and stool of healthy people after eating it. Twenty adults ate broccoli and gave blood and stool samples over 15 days. The goal was to see if these plant molecules might affect g…

This study looked at how two natural hormones, oxytocin and vasopressin, change brain activity and behavior in 120 healthy adults. Participants received the hormones as a nasal spray and then performed tasks while their brain waves were recorded. The goal was to understand how th…

This early-stage study tested two experimental drugs, JLP-2302 and JP-1366, in 55 healthy volunteers to see how the body processes them and if they are safe. Participants were adults with a normal body weight and no major health issues. The goal was to measure drug levels in the …

This study looked at how three drugs (JW0104, C2402, and JW0105) are processed by the body and whether they are safe. It involved 60 healthy adults who took single doses under fasting conditions. The goal was to measure drug levels in the blood, not to treat any disease.

This early-stage study tested the safety and tolerability of a new drug called PROT-001 in 102 healthy adults. Researchers also looked at how the drug behaves in the body and how it interacts with other common medicines. The goal was to gather safety information, not to treat any…

This study looked at how appetite, food intake, and energy use change across the menstrual cycle in healthy women aged 18-35. Researchers measured eating habits, metabolism, and body composition in two different phases of the cycle. The goal was to better understand the link betw…

This study tested whether a device called Seismofit can accurately measure fitness (VO2 Max) while a person rests, compared to the standard exercise test on a bike. Thirty healthy adults took part. The goal was to see if the Seismofit could be a simpler, faster way to check heart…

This study looked at how a single dose of the drug BI 1015550 moves through the bodies of 12 healthy Japanese men. The goal was to measure drug levels in the blood, not to treat any disease. Participants were healthy males aged 18 to 45 with a normal body weight.

This study looked at how a single dose of THC (the active ingredient in cannabis) changes immune-related genes and proteins in 56 adults—some with HIV and some without. Researchers measured gene activity and 45 immune signaling molecules before and after THC infusion. The goal wa…

This study looked at whether using a softer, more flexible IV catheter (cannula) reduces irritation and damage to veins compared to standard ones. Researchers placed one flexible and one standard catheter in each of 27 healthy adults and monitored them for up to 72 hours. The goa…

This early-stage study tested a mulberry twig alkaloid tablet (WH006) in 62 healthy and overweight/obese adults in China. The main goal was to check safety and how the drug moves through the body, not to treat or cure obesity. Participants took single doses, and researchers monit…

This study looked at how meditation changes the brain and helps with attention and emotions. Researchers used brain scans and stress tests on 169 healthy adults. The goal was to understand the science behind meditation's benefits for mental well-being.

This study looked at how interleukin-6 (IL-6), an immune system protein, changes the way glucagon lowers amino acid levels in the blood. Twenty-six healthy adults received either a dummy infusion or a drug that blocks IL-6, then had their hormone and amino acid levels measured. T…

This study looked at how healthy young women keep their balance, focusing on front-to-back and side-to-side stability. Researchers also checked if body weight affects balance. 111 women took part, and no treatments or interventions were given. The goal was simply to learn more ab…

This early-stage study tested a new inhaler (pMDI) against a standard one (Spiriva Respimat) in 40 healthy volunteers. The goal was simply to measure how much medicine gets into the blood, not to treat any disease. Participants took each inhaler for a short period, and researcher…

This study used MRI scans to measure how the index finger moves when pressed or pulled with small forces. Eight healthy adults participated. The goal was to collect data to create realistic computer models of the fingertip, which could help improve robotic hands or prosthetics.

This study checks if prazosin capsules made at a factory in Puerto Rico work the same as those made in Italy. About 69 healthy adults will take single doses of the capsules and have blood samples taken to measure how the drug is absorbed and cleared. The goal is to confirm the tw…

This study looked at how people with congenital amusia (tone deafness) process sound and memory compared to those without it. Researchers used brain scans like EEG, MEG, and MRI along with listening and memory tests. The goal was to better understand the brain differences behind …

This study looked at how sleeping at different altitudes affects oxygen levels and breathing in healthy people who live at moderate altitude. 44 adults had their sleep monitored at both low and moderate altitudes. The goal was to see if a short trip to lower altitude changes slee…

This study checked whether zongertinib tablets made by two different manufacturers are absorbed the same way in the body. Fifty-six healthy adults took a single dose of each version in random order. The goal was to see if the two versions are bioequivalent, meaning they work the …

This study looked at how two different forms of a drug combination (vicadrostat and empagliflozin) are absorbed in healthy adults. It also checked if taking the drug with food changes absorption. 32 healthy volunteers took a single dose and had blood samples taken. The study is c…

This study looked at how two experimental drugs (DWC202511 and DWC202512) change the way the body processes another drug (DWP16001) in 18 healthy adults aged 19 to 50. Participants took the drugs in a fixed order, and researchers measured drug levels in the blood. The goal was to…

This study looked at how evobrutinib, a potential multiple sclerosis drug, changes the way the body handles four common medicines: digoxin, metformin, rosuvastatin, and sumatriptan. Forty healthy adults took evobrutinib along with these drugs so researchers could measure their le…

This study looked at how the body handles MK-4482 in 16 healthy Chinese men after single and multiple doses. The main goal was to measure drug levels in the blood and check for side effects. This is an early-stage trial with no direct treatment benefit for participants.

This study looked at how a single dose of cenerimod is handled by the body in people with mild or moderate liver impairment compared to healthy volunteers. A total of 24 adults took part. The goal was to understand safety and how the liver affects drug levels, not to treat any di…

This early-stage study tested a new drug called FZ008-145 in 176 healthy adults to see if it is safe and how the body processes it. Researchers also measured pain tolerance using a cold water test. The goal was to gather basic safety information, not to treat any disease.

This completed study looked at the nutrition, emotional health, and physical safety of 40 people who work in the food supply chain. Researchers measured body composition, stress levels, and quality of life to find differences between active and sedentary workers. The goal was to …

This study is the first time the experimental drug RPT1G is being tested in humans. It involves 56 healthy adults aged 18 to 55 to see if the drug is safe and how the body processes it. Participants receive either the drug or a placebo, and no treatment benefit is expected.

This study looked at how two common drugs (itraconazole and rifampin) change the way the body processes KBP-5074. It involved 24 healthy adults aged 18 to 60. The goal was to measure safety and drug levels in the blood, not to treat any disease.

This study tested whether a 6-week smartphone app program could help high school athletes improve their agility and movement control. Nineteen athletes used the app to do exercises at home. Researchers measured how often they used the app and checked their movement before and aft…

This early-stage study tested a new drug called BI 706321 in 73 healthy men to see if it is safe and how the body handles it. Participants took a single dose of the drug or a placebo. The goal was to check for side effects and measure drug levels in the blood, not to treat any di…

This study tested whether a smartphone app called Flourish can help students feel better mentally. Over 1,100 students either used the app regularly or received standard mental health resources. Researchers measured changes in well-being, stress, anxiety, and depression over six …

This study looked at how using a smartphone changes the angle of your head and neck when sitting versus standing. Researchers measured 30 healthy adults aged 18-30 who use their phones daily. The goal was simply to observe and measure, not to treat or prevent any condition.

This study tested whether a generic gefitinib tablet works the same as the brand-name version (Iressa) in 38 healthy Chinese men. Each participant took one dose of each version after a meal, and researchers measured drug levels in the blood. The goal was to confirm the generic is…

This study looked at how different massage techniques at different times of day affect brain waves in 12 healthy male taekwondo athletes. Using EEG, researchers measured brain activity changes. The goal was to understand if massage timing matters for recovery, not to treat any di…

This early-stage study tested the safety and tolerability of a new drug called OPT101 in 14 healthy volunteers. Participants received either the drug or a placebo, and researchers monitored for side effects, vital signs, and lab changes. The goal was to find safe doses and unders…

This study looked at how two common antibiotics, amoxicillin and azithromycin, change the community of microbes living in our bodies and affect metabolism and immune function. Over 100 healthy adults took part, with some receiving antibiotics and others none. The goal was to unde…

This early-stage study looked at how the experimental drug DA-1229_01 moves through the body when taken with food. Thirty-six healthy adults each received a single dose and had their blood tested to measure drug levels and check for side effects. The goal was to gather safety and…

This study looked at two different tools—a force plate and a 3D camera system—to measure balance during walking in 50 healthy adults aged 20 to 40. The goal was to see which method gives more consistent results. This research helps improve how we study balance and prevent falls.…

This study looked at whether taking repeated cold or warm water baths helps healthy people recover muscle strength and soreness after exercise. Thirty healthy adults participated, and researchers measured muscle strength, soreness, swelling, and blood markers. The goal was to see…

This study looked at how disrupted sleep changes the way healthy adults feel pain and move their shoulders and knees. Thirty participants had their sleep interrupted and then received painful injections to measure their pain response. The goal was to understand the link between s…

This study tested two different injection methods for the drug tralokinumab in 101 healthy adults aged 18 to 55. The goal was to see if a single injection with one device works as well as two injections with another device. No treatment was given for any disease; the study only m…

This study looked at how different exercise programs affect the fitness and readiness of military trainees. 44 healthy adults aged 18-35 who were in a Reserve Officer Training Corps program took part. Researchers compared high-intensity functional training, traditional strength t…

This study looked at how temporary knee pain changes the way healthy people walk. Thirty-four adults received two types of knee injections—one that caused brief pain and one that did not. Researchers used motion-capture cameras and pain sensitivity tests to see how walking patter…

This study tested a new tablet that combines two drugs (etoricoxib and betamethasone) to see if it works as well as taking each drug separately. It involved 42 healthy adults who received single doses under fasting conditions. The goal was to measure how the drugs are absorbed an…

This study looked at how taking multiple doses of carbamazepine, a common seizure medicine, changes the amount of the cancer drug zongertinib in the blood. Sixteen healthy men received zongertinib once, then later took it again after several days of carbamazepine. The goal was to…

This study followed 373 healthy young athletes aged 8-16 for one year to see how sports specialization, performance, and quality of life relate to injuries. Researchers created athlete profiles and tracked injury types, locations, and recovery. The goal is to help young athletes …

This study looked at how quickly a new drug, LY3502970, gets into the bloodstream and how long it takes the body to clear it. It compared two new tablet forms to the original capsule in 26 healthy adults. The goal was to gather safety and drug-level information, not to treat any …

This study looked at how a new experimental drug (BI 1569912) changes the way the body processes three common medicines: repaglinide (for diabetes), midazolam (for sedation), and bupropion (for depression/smoking cessation). 18 healthy adults took the medicines alone and then aga…

This study tested whether two different tablet forms of the experimental drug HMPL-523 are absorbed similarly in the body. It involved 54 healthy Chinese adults aged 18-45. The goal was to check if the new tablet works like the original, not to treat any disease.

This study looked at how taking the drug BI 1015550 with or without food changes the amount of drug in the blood. 18 healthy adults took a single dose under both conditions. The goal was to see if food affects how the body absorbs the drug, which helps guide future dosing instruc…

This study looked at how a common antifungal drug (itraconazole) changes the levels of two experimental medicines, AVP-923 and AVP-786, in the blood. Twenty-four healthy adults took part. The goal was to gather safety and drug-interaction information, not to treat any disease.

This study looked at 80 adults aged 40-60 to see if sitting too much slows down gut transit time and changes gut bacteria in ways that might lead to colon polyps. Participants wore activity monitors, ate blue muffins to track digestion, and provided stool samples. The goal was to…

This study tested whether a gentle electrical current applied to the scalp (transcranial electrical stimulation) can improve performance on a challenging computer task that simulates docking a spacecraft. 44 healthy adults with advanced degrees completed the task while receiving …

This study tested whether a special headband that senses brain activity and a device that gently stimulates the ear could help healthy adults stay focused and feel less sick during virtual reality tasks. 45 volunteers completed attention and motion-sickness tests in VR while some…

This study tested three different tablet versions of the drug BI 425809 in 18 healthy adults to see if the body absorbs them similarly. Participants took a single dose of each version in random order, and researchers measured drug levels in the blood. The goal was to compare the …

This study looked at how a special low lactose milk with added GOS (a type of fiber) affects digestion in 24 healthy Chinese adults. Researchers used MRI scans to measure water content and movement in the gut after drinking the milk. The goal was simply to understand the digestiv…

This study looked at whether people with complex regional pain syndrome (CRPS) have trouble imagining movements, compared to healthy people and those with other muscle or bone pain. Researchers used a questionnaire to measure motor imagery skills in 129 adults. The goal was to be…

This study tested a new drug called LY3876602 in 74 healthy adults to see if it is safe and how the body handles it. Participants received either the drug or a placebo, and researchers measured how much drug got into the blood and spinal fluid. The goal was to gather safety infor…

This early-stage study tested a drug called BI 425809 in 25 healthy men to see how much of it reaches the brain and how the body processes it. Researchers measured drug levels in blood and spinal fluid after multiple doses. The goal was to gather safety data and understand the dr…

This study looked at how the way you apply antiseptics (like CHG and iodine) before surgery affects how well they kill germs. 122 healthy volunteers had the antiseptics applied in different ways to their skin. The goal was to see which method reduced bacteria the most, helping to…

This study looked at how kidney function affects the amount of a new medicine (BI 456906) in the blood. The medicine is being developed for obesity and liver problems. 42 adults with and without kidney issues received a single injection. Researchers compared blood levels across g…

This study tested whether a simple 2-week nature routine could improve spiritual well-being in healthy adults. 41 participants either took 30-minute contemplative nature walks or continued their normal routine. The goal was to see if being present and observing nature could enhan…

This study compared a new 3D-printed bike saddle with two popular racing saddles to see how they affect blood oxygen and carbon dioxide levels in the penis. Fourteen elite male road cyclists rode on a stationary trainer while sensors measured these gases. The goal was to understa…

This study looked at how the drug olomorasib moves through the body in 120 healthy adults. Participants took the drug by mouth and stayed overnight at the research center for 10 nights over about 7 weeks. The goal was to measure how much drug gets into the blood and how fast the …

This study looked at how a single session of low-intensity exercise with blood flow restriction (BFR) changes pain perception in 20 healthy young adults. Researchers used various sensory tests, like pressure and heat, to measure pain thresholds before and after exercise. The goal…

This study tested how well a heart monitor patch (MCT Patch) sticks to the skin for up to 30 days. Fifteen healthy adults wore the patch and reported on comfort and skin reactions. The goal was to see if the patch stays on long enough to record clear heart signals.

This early-stage study looked at how taking the drug BI 1015550 with or without food changes its levels in the blood. Twelve healthy men took the drug under both conditions to compare absorption. The goal was to gather information for future studies, not to treat any disease.

This study collects blood from 43 healthy adults aged 18-60 to serve as a comparison for tests that detect cancer cells in the blood. Participants complete a health questionnaire and donate about 20 mL of blood up to 20 times. The goal is to improve the accuracy of cancer detecti…

This study looked at whether getting protein from whole foods (lean red meat) is better than from a supplement (whey) for building muscle during resistance training. 81 moderately active adults did a 12-week exercise program and were assigned to eat lean red meat, take whey prote…

This study looked at how much iodine breastfeeding women need each day to keep both themselves and their babies healthy. Researchers measured iodine levels in 17 mother-infant pairs to find the right daily amount. The goal is to improve nutrition guidelines for moms who are exclu…

This study looked at how taking multiple doses of the antifungal drug itraconazole changes the way the body processes a single dose of an experimental cancer drug called zongertinib. Sixteen healthy men participated to measure drug levels in the blood. The goal was purely to gath…

This study looked at how caffeine changes oxygen levels in the brain while people do thinking tasks. 37 healthy adults aged 25-35 took part. Researchers used a special light-based technique (fNIRS) to measure brain activity. The goal was to understand the link between caffeine, b…

This study looked at how exercise changes molecules in the body, like proteins and stress hormones, in 80 healthy athletes. Researchers compared elite cyclists to recreational athletes during a bike test. The goal was to better understand the body's complex response to physical a…

This study looked at how a drug called ulonivirine moves through the body of 8 healthy adults. Researchers measured how much of the drug was absorbed, broken down, and eliminated in urine and stool. The goal was to understand the drug's path, not to treat any disease.

This study tested a new drug called LEO 153339 in 108 healthy adults to see if it is safe and how the body handles it. Participants received either one dose or multiple doses of the drug or a placebo. The goal was to check for side effects and measure drug levels in the blood, no…

This study measured how a single session of resistance exercise, with or without added stretching, affects blood vessel function and blood pressure in 27 healthy men. Participants were assigned to rest, exercise only, or exercise plus stretching, and were tested before, right aft…

This early-stage study tested the safety and how the body processes a new drug called ARC-520. Fifty-four healthy adults received either the drug or a placebo. The goal was to check for side effects and measure drug levels in the blood, not to treat any disease.

This study looked at how the drug calderasib is absorbed, distributed, and removed from the body in 8 healthy adults. Participants gave blood, urine, and stool samples over time to measure the drug and its breakdown products. The goal was purely to understand the drug's behavior,…

This study looked at how common prescription and over-the-counter medications affect mood and drug preference in 25 healthy adults. Participants rated how much they liked the drug and its perceived value. This is not a treatment study—it aims to understand medication effects on m…

This study looked at how a new drug, LY3502970, moves through the body and how long it takes to leave. Six healthy men took a single dose with a tiny radioactive tag so scientists could track it in blood, urine, and stool. The goal was to learn about the drug's breakdown and elim…

This early-stage study tested the safety and how the body processes a new drug called TML-6. It involved 72 healthy adults aged 18 to 80. The goal was to check for side effects and measure drug levels in the blood, not to treat any disease.

This study looked at how a drug called nirogacestat changes the way the body processes five other common medicines. Twenty healthy men took the medicines alone and then again while also taking nirogacestat. The goal was to see if nirogacestat speeds up or slows down the breakdown…

This study looked at how a single dose of the experimental drug MK-1084 changes the way the body processes two common medicines: rosuvastatin (for cholesterol) and metformin (for diabetes). Sixteen healthy adults took part in a crossover design where each person received the medi…

This study looks at how the experimental drug PF-07054894 is absorbed, broken down, and removed from the body. Ten healthy adult men will take the drug by mouth and receive a tiny radioactive tracer to track it. The goal is to learn about the drug's behavior, not to treat any dis…

This study looked at how healthy men absorb, break down, and eliminate a single dose of the experimental drug BI 1015550. Six participants provided urine and stool samples over several days to track the drug's path. The goal was to understand how the drug is processed and removed…

This early-stage study tested a new drug called ZE50-0134 in 104 healthy adults aged 18 to 55. The main goal was to check the drug's safety and how the body processes it, not to treat any disease. Participants took single or multiple doses by mouth, and some also took a stomach a…

This study looked at how branched-chain amino acids (BCAAs) help build muscle and process sugar in healthy young adults. Twenty-four volunteers drank a special amino acid drink, and researchers measured muscle protein growth and insulin sensitivity. The goal was to understand the…

This study looked at how reliably we can measure tongue muscle strength and endurance in healthy children aged 4 to 17. Researchers tested children twice to see if the results were consistent. The goal was to improve future assessments of tongue function, not to treat any conditi…

This study looked at how a new drug called CKD-508 interacts with two other medicines (midazolam and rosuvastatin) in 24 healthy adult men. The goal was to measure drug levels in the blood, not to treat any disease. Participants took the drugs in a set order, and researchers chec…

This study tested how tolerable transcranial magnetic stimulation (TMS) feels on different scalp locations and with different stimulation patterns. Twenty healthy adults rated their discomfort using a pain questionnaire. The goal was to find the most comfortable ways to deliver T…

This study looked at how the drug olomorasib enters the bloodstream and how long it takes the body to remove it in people with mild, moderate, or severe liver problems compared to healthy people. 46 adults took a single dose and were monitored for up to 6 weeks. The goal was to g…

This early-stage study tested the safety of a new drug, NEU-627, in 74 healthy adults aged 18 to 60. Participants received either the drug or a placebo to see how the body handles it and if any side effects occur. The study is complete and does not aim to treat any disease.

This study looked at whether taking multiple doses of the experimental drug BI 425809 changes how the body handles a common birth control pill (Microgynon®) in 19 healthy premenopausal women. The goal was to measure drug levels in the blood to see if there is an interaction. This…

This study looked at how healthy young adults (ages 18-45) felt during upper body versus lower body cycling when electrical muscle stimulation was used. Researchers measured perceived exertion, fatigue, and energy levels. The goal was to understand how these exercises compare, wh…

This early-stage study tested a new drug called LY3985863 in 24 healthy Chinese adults to see if it is safe and what side effects it might cause. Participants received multiple doses under the skin or a placebo. The study did not aim to treat any disease, but to gather informatio…

This study looked at how to best prepare blood platelets (small cells that help with clotting) to measure their mitochondria, the tiny powerhouses inside them. Researchers collected blood from 16 healthy adults aged 25-35 and tested different lab methods. The goal was to make sur…

This study looked at how evobrutinib, an experimental drug, changes the way the body processes a common birth control pill. Twenty healthy women took both medications and had their blood levels measured. The goal was to see if the birth control still works properly when taken wit…

This study looked at whether using a special cuff to partly block blood flow during low-weight exercises can build strength as well as traditional heavy weight training. Sixteen healthy adults aged 18 to 40 took part, and researchers measured changes in force, power, and speed ov…

This early-stage study tested the safety and how the body processes a single dose of ARC-520 given at different speeds. It involved 40 healthy adults aged 18 to 55. The goal was to check for side effects and measure drug levels in the blood, not to treat any disease.

This study tested an experimental drug called LY3522348 in 65 healthy people to see if it is safe and what side effects it might cause. Researchers also measured how much of the drug gets into the blood and how quickly the body removes it. The study had two parts, lasting up to 8…

This study looked at whether taking sodium bicarbonate (baking soda) before exercise helps well-trained cyclists perform better during a long, simulated race. Nineteen cyclists did two sessions of three hours of moderate cycling followed by a hard time trial, taking either the su…

This study looked at how ketamine changes activity in brain areas linked to reward and emotion. Thirteen healthy adults who had used ketamine before underwent brain scans while doing tasks. The goal was to understand ketamine's effects on brain circuits, not to treat any disease.

This study looked at how healthy adults process a compound called ornithine phenylacetate (OP), which is being studied for liver disease. Twenty volunteers aged 40-70 received special tracers and took OP by mouth. Researchers collected blood, urine, and muscle samples to track ho…

This study looked at how naloxone (a drug that reverses opioid overdoses) behaves in the body when given as a nasal spray or through an IV. Eight healthy adults took part to help researchers build better computer models for predicting how the drug reaches the brain. The goal was …

This study looked at how the brain works during arm movements in people who had a stroke and in healthy volunteers. Researchers used a brain imaging technique called fNIRS to measure activity while participants moved their arms with different levels of effort. The goal was to bet…

This study looked at healthy women aged 30-60 who either started intermittent fasting (eating only during an 8-hour window) or quit smoking. Researchers checked if these lifestyle changes affected DNA methylation patterns linked to aging and cancer risk over 6 months. Participant…

This early-stage study tested a single dose of the experimental drug MT-8554 in 20 healthy men. The goal was to see how the drug affects the body's response to pain, measured by a cold water test, and to check for any safety issues. This trial did not involve treating a disease, …

This study aimed to create a reference range for nerve fiber density in the skin using biopsies from 300 healthy adults aged 20-80. By measuring these fibers with microscopes, researchers hope to improve diagnosis of small fiber neuropathy, a condition causing pain and numbness. …

This study looked at how the drug MK-1084 (calderasib) behaves in people with moderate or severe kidney problems compared to healthy people. Researchers measured drug levels in the blood over time and checked for side effects. The goal is to understand if kidney impairment change…

This study tested three different versions (formulations) of an experimental drug called BI 456906 in 30 healthy adults. The goal was to see how well each version is absorbed into the body. Participants received a single dose of each version in random order. The results will help…

This study aimed to find the best way to recruit nurses and nursing assistants from other European Union countries to work in Denmark. Over 110,000 people were sent different recruitment messages on social media to see which messages got the most responses. The study did not test…

This study looked at how a new HIV medicine (MK-4646) interacts with a tuberculosis drug (rifabutin) in 18 healthy adults. Researchers measured drug levels in the blood and checked for side effects when MK-4646 was taken alone and with rifabutin. The goal was to understand if the…

This study looked at how a new drug called imlunestrant affects the way the body processes another drug, midazolam, in 20 healthy women who cannot become pregnant. The goal was to understand potential drug interactions and check for safety. Participants took both drugs and had th…

This study looked at whether taking arginine supplements can prevent blood vessel damage caused by the NSAID painkiller celecoxib. 44 healthy men took celecoxib with either arginine or a placebo for a week. Researchers measured changes in blood vessel function and stiffness to se…

This study checked whether a single dose of evobrutinib affects the heart's electrical activity (QT interval) in 36 healthy adults. Participants received evobrutinib, a placebo, or a positive control in random order. The goal was to see if the drug causes heart rhythm changes, no…

This study looked at how people with dystonia, essential tremor, or Parkinson's disease adapt their eye movements compared to healthy volunteers. Researchers used a simple eye-tracking task to measure changes in saccade (quick eye movement) accuracy. The goal was to better unders…

This study tested whether a 1-minute 51-second animated video called FAST BEE helps people remember stroke warning signs and what to do. Over 300 healthy adults and teens watched the video and answered questions about recall, applying the signs to a scenario, and their intent to …

This study looked at whether patterns in cell phone use (like calls, texts, and movement) relate to daily changes in blood pressure and metabolism. Six healthy adults aged 25-35 used an Android app to share their phone data while researchers monitored their blood pressure and col…

This study looked at whether a supplement called OliPhenolia®, made from olive polyphenols, can reduce inflammation and help healthy adults recover after exercise. 18 participants took either the supplement or a placebo before and after a standard workout. Researchers measured bl…

This study looked at how healthy young women's muscles build and break down proteins during exercise and when one leg is kept still. Fifteen women took part to help scientists understand the basic processes behind muscle growth and loss. The goal is to find new ways to prevent mu…

This study tested a new blood collection device called Tasso+™ to see if it works as well as standard blood draws. 200 healthy adults provided blood samples using both methods. The goal was to check if the device can be used reliably in clinics or at home for future trials and pa…

This study looked at how a 40-minute afternoon nap affects communication between brain regions involved in daydreaming and self-awareness. Researchers scanned the brains of 55 healthy adults before and after their nap to see if connections weakened. They also checked whether peop…

This study looked at how food and a common stomach acid drug (esomeprazole) affect the way the body handles a single dose of LY4064809 in 36 healthy adults. Participants took the drug under different conditions, and blood tests measured drug levels. The goal was to gather safety …

This study looked at how small genetic differences in the GLP-1 receptor affect insulin production in healthy adults. Researchers compared two groups of people with different gene versions to see how their bodies released insulin when fasting and when blood sugar was high. The go…

This study looked at whether cooling the body for 20 minutes before or after exercise helps healthy young adults recover faster and perform better. Twenty-two participants did jumping and strength tests, and rated their muscle soreness and effort. The goal was to see if cryothera…

This study looked at how healthy men absorb, break down, and get rid of a drug called MK-5475. Eight participants received a single dose, and researchers measured the drug in blood, urine, and stool. The goal was simply to learn more about the drug's journey through the body, not…

This early-stage study tested a new drug called SR750 in 40 healthy Chinese adults aged 18 to 45. The goal was to measure how the drug moves through the body and check for any side effects. Participants received either the drug or a placebo, and no treatment for any disease was i…

This study looked at whether using asthma inhalers for 4 weeks changes blood vessel and heart function in healthy adults aged 18-40. Participants used either a common inhaler (Ventolin or Symbicort) or a placebo and had tests like ultrasounds and exercise checks. The goal was to …

This study checked whether a single dose of the experimental drug BI 1015550 affects the heart's electrical activity in 46 healthy adults. Participants received low and high doses of the drug, a placebo (dummy pill), and an active control to compare results. The goal was to see i…

This study looked at whether watching someone else perform reaching movements can improve your own ability to do the same task. Sixty healthy adults were split into three groups: one watched arm movements, another watched light sequences, and a third watched nature videos. Their …

This study looked at how raising the head of the bed changes lung movement in 31 healthy adults aged 18 to 60. Researchers used a painless ultrasound to measure lung sliding at three different bed angles: flat, 20 degrees, and 40 degrees. The goal is to help doctors position pati…

This small pilot study tested whether stimulating a nerve in the ear (the auriculotemporal nerve) with mild electrical pulses can change how healthy people process pain. Twelve volunteers without pain received two types of stimulation on different days, and researchers measured t…

This completed study tested a new computer system that uses real-world patient data and artificial intelligence to help doctors more accurately diagnose and treat complex brain disorders like dementia, epilepsy, and sleep problems. Researchers collected information from 635 peopl…

This early-stage study tested the safety and how the body processes a new drug called AVP-786. Forty-eight healthy adult men took single or multiple doses of the drug or a placebo. The goal was to measure drug levels in the blood and check for any side effects, not to treat any d…

This study looked at how taking bosentan (a drug that can speed up how the body breaks down other medicines) changes the amount of BI 425809 in the blood. Fourteen healthy men took BI 425809 alone and then again with bosentan. The goal was to see if bosentan lowers the levels of …

This study tested whether healthy adults can learn to increase communication between brain regions using neurofeedback—a technique that shows real-time brain activity. Researchers wanted to see if this improved visual perception and motor learning. The study involved 65 healthy p…

This study looked at how healthy adults absorb and process the experimental drug LY4268989 (MORF-057) and checked for any side effects. About 144 healthy volunteers, including people of Japanese and Chinese descent, took part. The goal was to gather safety and drug-level informat…

This study looked at whether a small device placed on the skin (Tasso) can collect blood samples as accurately as a standard needle from a vein. Fourteen healthy adults took zavegepant nasal spray, and their blood was tested using both methods. The goal was to see if the simpler,…

This early-stage study involved 39 healthy adults to see how two different versions of the experimental drug LY3502970 behave in the body. Researchers measured drug levels in the blood and checked for safety. The study lasted up to 13 weeks and did not aim to treat any disease.

This study tested whether brain stimulation works better when you're actively using the brain area being stimulated. 51 healthy adults received transcranial magnetic stimulation (TMS) while doing a thinking or a seeing task. Researchers measured brain activity changes right after…

This study tested whether drinking camel milk after intense cycling helps healthy men recover better than cow's milk or water. Twelve recreationally active males completed cycling tests and had their muscle soreness, damage, and inflammation measured. The goal was to see if camel…

This study looked at how the body absorbs frankincense, lemon, and wild orange essential oils when taken in different types of capsules. Nineteen healthy adults aged 18-35 took part. Researchers measured oil levels in the blood over 24 hours and checked safety markers like liver …

This completed Phase 1 trial enrolled 14 healthy adults to find out if taking BI 764198 along with metformin affects the amount of metformin in the blood. Participants received metformin with and without the study drug in a crossover design. The study measured drug levels and kid…

This study looked at how a drug called LY3484356 enters the bloodstream and leaves the body in 16 healthy women who cannot become pregnant. Participants took a single dose with a tiny radioactive marker to track the drug and its breakdown products in blood, urine, stool, and brea…

This study looked at how a drug called belzutifan affects the amount of metformin in the blood and urine of healthy adults. Fourteen volunteers took metformin alone and then metformin with belzutifan, and researchers measured the drug levels. The goal was to understand the intera…

This study tested whether adding a steady beat (metronome or music) to eye-head exercises helps healthy adults improve the reflex that keeps vision clear during movement. Twelve participants completed three training sessions—silence, metronome, and music—while wearing goggles tha…

This early-stage study tested a new compound called LEO 158968 in 120 healthy adults aged 18 to 60. The main goal was to check for side effects and see how well the drug is tolerated, as well as how the body absorbs, distributes, and gets rid of it. Participants received either s…

This study looked at how different carbon fiber brace designs change the forces on the ankle joint. Nine healthy adults wore braces while walking, and researchers used computer models to estimate joint stress. The goal was to improve the model so future braces can be designed to …

This early-stage study tested the safety and how the body processes a single dose of the drug BI 425809 in 49 healthy Japanese and Chinese men. Participants received either the drug or a placebo, and researchers monitored side effects and drug levels in the blood. The goal was to…

This study looked at how different amounts of a maqui berry extract called Delphinol affect blood vessel function. Ten healthy adults took 60 mg, 120 mg, 180 mg, or a placebo daily for eight days each. Researchers measured blood flow and other markers to find the best dose for va…

This study looked at how the cancer drug selpercatinib changes the way the body processes midazolam, a common sedative. Sixteen healthy adults took both drugs in a fixed order, and researchers measured drug levels in the blood. The goal was to understand potential interactions so…

This completed Phase 1 study looked at how two experimental drugs, denifanstat and resmetirom, affect each other in the body. It involved 40 healthy adult volunteers. The goal was to measure drug levels in the blood to see if taking them together changes how each one works.

This study aims to create a test that uses time estimation and emotional video clips to detect early emotional problems in people with neurological diseases. First, researchers need to establish normal reference values by testing 150 healthy adults aged 20 to 92. Participants wat…

This study looked at 46 healthy young adults to see if the size of their arms, forearms, and hands relates to how well they perform tasks like placing pegs and catching a ruler. Researchers measured arm lengths and circumferences, then tested hand skills and reaction time. The go…

This study looked at how a new drug called BI 425809 changes the way the body processes another drug, midazolam. Fifteen healthy men took both drugs to see if there is a risk of interaction. The goal was to gather information for safe future use, not to treat any disease.

This study tested whether an audio instructional program about puberty could improve self-concept and healthy behaviors in teenage girls with visual impairment. 46 girls aged 12-18 from two schools in Egypt participated. The program aimed to fill a gap in accessible puberty educa…

This study looked at how the drug cyclosporine changes the amount of a new medicine (LY3502970) in the blood of 32 healthy adults. Participants took LY3502970 alone and then with cyclosporine so researchers could compare the levels. The goal was to gather safety and drug interact…

This study tested a portable headset that sends tiny electrical currents through the skin to help people hear sounds and speech. Researchers worked with 68 healthy adults to find the best settings for the device. The goal was to see if this noninvasive approach could improve hear…

This early-stage study tested a new drug called KBP-5074 in 46 healthy adults to see if it is safe and how the body processes it. Researchers also looked at how food affects the drug and measured certain body chemicals to help plan future studies. The goal is to find the right do…

This study looked at how well a non-invasive device (thoracic electrical bioimpedance) measures stroke volume—the amount of blood the heart pumps with each beat—in healthy people at rest and during exercise. Twelve volunteers (6 men, 6 women) completed exercise tests on a station…

This early-stage study in 6 healthy male volunteers measured how much of the experimental drug BI 425809 enters the bloodstream after being taken as a pill compared to a tiny radioactive dose given directly into a vein. The goal was to understand the drug's oral bioavailability —…

This study tested two ways of teaching nursing students how to manage fluid and electrolyte balance in a child trapped under rubble. 69 students were split into three groups: one got traditional classroom training, another got simulation-based training, and a third got no trainin…

This study looked at how elpipodect moves through and leaves the body of 6 healthy adults. Researchers measured the drug in blood, urine, and stool to understand its absorption and breakdown. The goal was purely to gather information, not to treat any disease.

This study looked at how two different versions of the drug sotatercept behave in the body. 146 healthy women who cannot become pregnant received either a liquid form in an autoinjector or a powder form that was mixed before injection. The goal was simply to compare the two forms…

This study looked at how taking multiple doses of an experimental drug called BI 1015550 changes the way the body processes another drug, midazolam. Fifteen healthy men took midazolam alone and then again after taking BI 1015550. The goal was to see if BI 1015550 speeds up or slo…

This early-stage study tested the safety of a new drug called MORF-440 in 80 healthy adults. Participants received either a single dose or multiple doses to see how the body handles the drug and if any side effects occur. The study does not aim to treat any disease, but to gather…

This study tested how taking multiple doses of itraconazole, a strong CYP3A4 inhibitor, changes the way the body processes a single dose of BI 3031185. Fourteen healthy male volunteers participated. The goal was to measure drug levels in the blood to understand potential interact…

This study aims to find better ways to measure and understand myofascial pain syndrome, a common muscle pain condition. Researchers used advanced imaging techniques like ultrasound and bioimpedance in 96 adults to look at muscles, connective tissue, and blood flow. The goal is to…

This study looked at how a new drug called BI 1291583 is broken down and removed from the body. Eight healthy men took a single dose with a radioactive tracer so scientists could track it in urine and stool. The goal was to understand the drug's metabolism and recovery, not to tr…

This study looked at how Swedish massage and percussion therapy affect muscle stiffness, soreness, and jumping ability after exercise in 24 healthy adults aged 18-30. Participants received one of the two treatments after a workout, and researchers measured muscle properties and s…

This study looked at how two parts of the brain, Broca's area and the mid-cingulate cortex, work together to control speech. Researchers used brain scans (fMRI) on 23 healthy, right-handed adults while they performed tasks. The goal was to learn more about the basic brain functio…

This study examined how a specific airway clearance technique (ELTGOL) changes air distribution in the lungs of people with COPD and healthy individuals. Researchers used a special imaging method to measure lung ventilation while participants lay on their side. The goal was to un…

This completed Phase 1 study involved 8 healthy men to find out how much of the drug BI 1015550 gets into the blood after taking it by mouth. Participants received a single oral dose plus a tiny radioactive tracer dose by IV. The goal was purely to understand the drug's behavior,…

This study looked at how a gentle electrical current applied to the scalp changes brain activity and chemistry in 37 healthy adults. Using advanced brain scans, researchers measured blood flow, connections between brain regions, and dopamine levels during and after a single 30-mi…

This early-stage study tested a new drug called HEC30654AcOH in 43 healthy adults to see if it is safe and how the body processes it. Participants received either single or multiple doses of the drug. The goal was to check for side effects and measure drug levels in the blood, no…

This study looked at how a single dose of the drug MCI-186 is processed by the body in people with mild or moderate kidney problems compared to those with normal kidneys. Thirty adults took part, and researchers measured drug levels in the blood over time. The goal was to underst…

This study looked at how a single dose of the drug Selpercatinib affects the heart's electrical activity in 32 healthy adults. Participants received the drug, a placebo, or another control in random order. The goal was to check for any heart rhythm changes, not to treat any disea…

This study looked at how two different forms of MDMA (R-MDMA and S-MDMA) affect healthy people. Researchers measured feelings like mood and trust, as well as heart rate and blood pressure. The goal was to understand which form might be better for use in therapy for conditions lik…

This study followed 191 healthy teens who were part of the original Beginnings study as babies. Researchers measured their growth and body composition to see if early infant diet influences development at age 14. No treatments or interventions were given—just observation and meas…

This study followed 2760 healthy infants from birth to age 3 to understand how nutrition affects their gut bacteria and bone development. Researchers measured the babies' gut microbiome, diet, and bone growth using ultrasound. The goal was to map normal development patterns and s…

This study developed a method to measure how the body breaks down tryptophan, an essential nutrient. Ten healthy adults aged 18-45 took a special tracer, and researchers tracked its byproducts in blood and urine. The goal is to use this method later to improve nutrition for prete…

This study tested two new foam bandages on healthy volunteers to see if they stay in place as well as current bandages. 135 people wore the dressings on their knee or thigh for up to 7 days. The main goal was to check if the new bandages stayed put without the edges lifting or th…

This study looked at how the body absorbs empagliflozin (a diabetes drug) when taken as a whole tablet versus dissolved in water and mixed with food. Fourteen healthy adults participated in this two-period crossover trial. The goal was to measure drug levels in the blood to see i…

This study measured how a radioactive tracer called [18F]PBR111 spreads through the body and how much radiation it gives off. Six healthy adults (3 men, 3 women) received the tracer and had PET/CT scans for about 2 hours. The goal was to check safety and calculate radiation expos…

This study looked at how a drug called LY3537031 moves through the body in people with different levels of kidney function. Researchers compared 31 adults with normal kidneys to those with kidney problems or end-stage kidney disease. The goal was simply to gather information, not…

This study tested whether treating fruits like lemons and cherries with melatonin helps the body absorb more healthy plant compounds. Twenty-two healthy adults drank juice from treated or untreated fruits and provided urine samples. The goal was to see if melatonin changes how mu…

This study looked at how two different capsule forms of the drug olomorasib behave in the body and whether food changes drug levels. It involved 191 healthy Japanese participants over about 6 weeks. The goal was to gather information, not to treat any disease.

This study tested a new furosemide injection given under the skin versus the standard IV version in 16 healthy adults. The goal was to see how well the body absorbs the drug and how it works. Results will help decide if the shot is a good alternative for patients who need this me…

This early-stage study tested the safety and tolerability of a new drug called SPY001-001 in 96 healthy adults. Participants received either the drug or a placebo, and researchers monitored side effects and how the drug moved through the body. The goal was not to treat any diseas…

This study looked at whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can improve aerobic and anaerobic fitness in healthy athletes. 59 athletes aged 18-25 or 40-50 who exercise regularly took part. Researchers measured changes in exercise capaci…

This study looked at how a new drug called BI 425809 changes the way the body processes four common medicines (midazolam, warfarin, omeprazole, and digoxin). Thirteen healthy men took these medicines with and without BI 425809 to see if their levels in the blood changed. The goal…

This study looked at how sleep helps the brain remember and improve motor skills that were learned just by imagining the movements. 51 healthy right-handed adults practiced finger sequences or adaptation tasks mentally, then slept. Researchers used MEG brain scans to see which br…

This study looked at 27 elite rowers to see if low energy availability affects brain chemicals like serotonin and dopamine, and how that relates to performance and recovery. Participants did a standard exercise test, and researchers measured their stress hormones, mood, and recov…

This study tested whether adding arm exercise to leg exercise helps healthy individuals endure a workout longer than leg exercise alone. Ten healthy adults participated in cycling endurance tests. The goal was to see if this combined approach could later help people with lung dis…

This early-stage trial studied 16 healthy men to see how the antibiotic rifampicin changes the way the body processes a single dose of BI 425809, a drug being developed for cognitive problems. Participants took BI 425809 alone and then again after several days of rifampicin. The …

This early-stage study looked at how a single dose of the experimental drug LY3526318 affects blood flow in the skin of healthy women. Researchers used special imaging to measure changes after applying a cinnamon-like substance. The study involved 16 participants and lasted up to…

This study looked at how a common antifungal drug (itraconazole) changes the way a new experimental drug (BI 1015550) is processed in the body. Sixteen healthy men took BI 1015550 alone and then again while also taking itraconazole. The goal was simply to measure drug levels in t…

This study looked at how the drug quinidine changes the amount of orforglipron in the blood of 27 healthy adults. Researchers measured drug levels over time to see if quinidine affects how the body processes orforglipron. The goal was to gather safety and dosing information, not …

This study looked at how LED light affects skin healing in 10 healthy adults. Participants had small laser spots on their forearms, then received LED treatment. Researchers measured skin color and water loss to see if LED helped healing. The goal was to find the best LED settings…

This early-stage study tested a new drug called DA-7503 in 90 healthy adults and elderly volunteers to check its safety and how the body processes it. Participants took either the drug or a placebo by mouth. The goal was to gather basic safety information, not to treat any diseas…

This study looks at how the antifungal drug fluconazole changes the amount of olomorasib in the blood and how fast the body clears it. Fifteen healthy adults will stay overnight at the research center 12 times over about 7 weeks. The goal is to gather safety and drug-level data, …

This early-stage study tested the safety and drug interaction of epaminurad and naproxen in 57 healthy adults aged 19 to 50. Participants were Korean or Caucasian and received the drugs to measure how the body processes them. The study was completed and aimed to gather safety dat…

This study looked at how different nutrients change the types and activity of gut bacteria. Instead of having people eat the nutrients, researchers added them to fecal samples in a lab dish that mimics the human colon. The goal was to understand which nutrients help grow healthy …

This early-stage study tested the safety of a new drug called MT-8554 in 135 healthy adults. Researchers checked vital signs, heart activity, and lab results to see how the drug affected the body. The goal was not to treat any disease but to gather basic safety information.

This study tested how to best apply STAR particles—very small particles covered in microneedles—to healthy skin. The particles create tiny punctures that may help topical medications work better in the future. Twenty healthy adults aged 18–39 had the particles applied to differen…

This study looked at how children's brains work when they use deductive reasoning (logical thinking) and how that relates to their math skills. Researchers used brain scans (fMRI) on 137 healthy children aged 8 to 14 while they solved reasoning problems. The goal was to find whic…

This early-stage study tested an experimental drug called AVP-786 in 56 healthy adult men. The goal was to measure how the drug moves through the body and check for any side effects. Participants took the drug and provided blood samples, with no direct health benefit expected.

This study tested a new, all-in-one breathing exercise device made in Turkey. It combines features of two existing devices to strengthen breathing muscles and improve lung ventilation. Forty healthy adults used either the new device or standard devices for 8 weeks. Researchers me…

This pilot study involved 6 healthy women who ate breakfast biscuits made with a special type of wheat bran that was labeled with a carbon tracer. Researchers then collected breath, urine, blood, and stool samples over 24 hours to track how the body breaks down the fiber. The goa…

This study tested if a safe, radiation-free device called electrical impedance tomography (EIT) can detect lung damage in children and young adults with cystic fibrosis. Researchers compared EIT results to CT scans to see if it can spot air trapping and other lung problems. The g…

This study looked at whether a simple brain wave test (EEG) can predict what is happening in a key brain network (the default mode network) measured by fMRI. Twenty-four healthy adults did attention tasks while their brain activity was recorded with both EEG and fMRI. In a second…

This study looked at how the drug bosentan changes the way the body processes nerandomilast in 16 healthy men. The goal was to see if bosentan speeds up the breakdown of nerandomilast, which could affect how well it works. Participants took bosentan for several days and then a si…

This study tested whether a new generic version of a Parkinson's disease drug (pramipexole extended-release) works the same as the brand-name drug (MIRAPEX ER). It involved 49 healthy Chinese adults who took a single dose of each version under fasting and fed conditions. The goal…

This study looked at brain activity in 29 healthy, right-handed adults during real hand movements and during the illusion of movement caused by vibrating a tendon. The goal was to find the smallest number of repeated tests needed to get clear brain signals. The results will help …

This study tested a new version of a breast cancer drug (CT-P6) against the approved version (Herceptin) in 200 healthy men. The goal was to see if the two drugs behave similarly in the body and have similar safety. Participants received a single injection and were monitored. Thi…

This early-stage study tested an investigational antifungal drug called fosmanogepix in 54 healthy Chinese adults. The goal was to see how the drug moves through the body and whether it is safe when given as a single dose or multiple doses, either by IV or by mouth. Participants …

This study looked at whether special physical activity cards, combined with Life Kinetik exercises, could improve attention, memory, and problem-solving in healthy 11-14 year old students. 36 middle schoolers participated, and researchers measured their cognitive skills before an…

This study looked at how the human brain supports tool use and the ability to make tools better over time. Researchers used brain scans (fMRI) on 70 healthy, right-handed adults aged 18 to 65. The goal was to understand which brain areas are unique to humans and help us use and i…

This study measured how fast 1000 healthy adults can walk a figure-8 path around two cones. The goal was to establish normal reference values for this walking test. Participants were over 18, had no known muscle, bone, or nerve problems, and were not elite athletes.

This study looked at how the drug MDMA changes brain activity related to risk and reward. Twenty-two healthy adults who had used MDMA before took part. Researchers used brain scans to measure responses to emotional faces and resting brain activity. The goal was to understand the …

This study looked at how the drug MCI-186 is processed in people with mild or moderate liver problems compared to healthy adults. A total of 22 participants received a single dose of the drug through an IV. The goal was to understand how liver function affects drug levels in the …

This study looked at how healthy men absorb, break down, and eliminate a drug called BI 425809. Six men took a single dose, and researchers measured the drug and its byproducts in urine and stool. The goal was to understand the drug's journey through the body, not to treat any di…

This early-stage study tested a new drug called BI 425809 in 83 healthy men to see if it is safe and how the body processes it. Researchers also compared a liquid form to a tablet and checked if taking it with food changes drug levels. The goal was to gather basic safety and dosi…

This study looked at whether the order in which elite female athletes eat their food—specifically, eating carbs at the end of a meal versus at the start—changes their blood sugar levels throughout the day. Twenty-two healthy athletes wore a continuous glucose monitor for six days…

This study looked at how Netherton syndrome (a rare genetic skin disorder) develops over time and how it affects the immune system. Researchers measured immune markers in the blood and tracked skin changes in 18 people with the condition. No new treatments were tested; the goal w…

This study aims to understand how the brain's connections change with age. Ten healthy volunteers aged 18 to 50 will have MRI scans to map their brain networks. The goal is to develop better markers for healthy brain aging, not to treat any disease.

This study tested a new drug called LY3985297 in 140 healthy adults to see if it is safe and how the body handles it. Participants received either a single dose or multiple doses through an IV or injection under the skin. The goal was to check for side effects and measure drug le…

This study looks at how early childhood development influences the formation of healthy, stable romantic relationships in young adulthood. It involves 259 participants from a previous child development study and their live-in partners. Participants complete online questionnaires …

This study looked at how the drug bulevirtide enters and leaves the bloodstream in people with healthy livers and those with liver problems. Researchers measured drug levels and bile acids, and checked for side effects. 74 adults took part to help understand dosing for future tre…

This study tested how much of the drug tacrolimus gets into the blood when applied to healthy skin. Twenty-four healthy adults applied the ointment twice daily for 14 days. Researchers measured drug levels and checked for side effects. The goal was to understand safety and absorp…

This study looked at 30 women — half with lipedema and half without — to measure differences in leg muscle strength, endurance, walking ability, pain sensitivity, and swelling. Researchers used simple tests like a 30-second sit-to-stand and a 6-minute walk, plus a device to measu…

This early-stage study tested whether a new eye drop called PRO-232 is safe and tolerable in 28 healthy adults aged 18 to 45. Participants received either the active drop or a placebo (inactive drop). Researchers monitored for side effects, eye pressure changes, and stinging. The…

This study looked at whether a short session of neck stretching can quickly lower blood pressure in healthy adults. Researchers measured blood pressure, tissue stiffness, and heart rate in 25 volunteers before and after stretching. The goal was to see if stretching could be a sim…

This early-stage study tested an experimental drug called BI 3810477 in 47 healthy adults aged 18 to 60. The goal was to see if multiple doses are safe and how the drug moves through the body. No treatment for any disease was studied, so this trial helps gather important safety i…

This study looked at how the drug MCI-186 moves through the body in people with severe liver damage compared to those with healthy livers. Twelve adults took a single dose, and researchers measured drug levels and side effects. The goal was to understand how liver problems affect…

This study looked at whether different doctors can consistently measure certain angles in the pelvis and hip on X-rays taken while sitting and standing. 33 healthy adults without any spine, hip, or pelvis problems participated. The goal was to see if these measurements are reliab…

This study looked at two different ways to give oxygen to healthy adults before a medical procedure. Thirty volunteers received oxygen through a mask alone or with a special nose tube. Researchers measured oxygen levels in their breath to see which method worked better. The study…

This study looked at how the drug KBP-5074 behaves in people with moderate liver damage compared to healthy people. Twelve adults took a single dose, and researchers measured drug levels and safety. The goal is to understand if liver problems change how the drug is processed, whi…

This study looked at 401 medical students to see how many had protection against hepatitis B and varicella-zoster (the virus that causes chickenpox and shingles). Researchers measured immunity levels and checked vaccination rates. The goal was to find gaps in protection and help …

This study looked at how the brain's electrical activity changes when healthy people become mentally or physically tired. Researchers used non-invasive brain scans (EEG and MEG) to find patterns linked to fatigue. The goal was to better understand these signals, not to treat any …

This study looked at how taking multiple doses of zongertinib changes the way the body processes three other drugs: midazolam, omeprazole, and repaglinide. Sixteen healthy men aged 18 to 55 took part. The goal was to see if zongertinib affects how these drugs are absorbed and cle…

This study looked at whether a serotonin receptor called 5-HT7 could be used as a biomarker for multiple sclerosis (MS). Researchers measured how much of this receptor was on different blood cells from 100 people, including healthy volunteers and MS patients on stable treatment. …

This early-phase study at Yale University tested whether a single dose of cannabidiol (CBD) could change brain inflammation and pain sensitivity in 28 healthy adults. Researchers used brain scans to measure inflammation and a capsaicin (chili pepper) cream to test pain response. …

This study tested a new, painless ultrasound method to measure tongue stiffness and fat content in 55 healthy adults aged 18-45. The goal was to create a standard protocol for future research on tongue fat accumulation, which is linked to sleep apnea. Participants lay on their ba…

This study looked at how having a meal affects appetite and eating behaviors in 33 healthy adults. Participants completed questionnaires and had blood tests before and after eating to measure hunger, fullness, and related hormones. The goal was to understand if a single meal chan…

This study tested the safety and side effects of a single dose of lebrikizumab (given as a shot under the skin) compared to a placebo in 24 healthy Chinese adults. Researchers also measured how fast the drug enters the blood and how long it stays in the body. The study did not ai…

This study looked at whether giving ketanserin, olanzapine, or lorazepam after taking LSD could make the LSD experience shorter or less intense. Twenty healthy adults took part. The goal was to understand how these drugs interact with LSD, not to treat any disease.

This early-stage study tested the safety of a new drug called THB335 in 60 healthy adults. Participants received either the drug or a placebo, and researchers monitored side effects and how the drug moved through the body. The goal was to gather safety information, not to treat a…

This study tested whether a single pill containing two heart medicines (ticagrelor and aspirin) works the same in the body as taking the two pills separately. Twenty-four healthy adults in Mexico took both forms and had their blood levels measured. The goal was to see if the comb…

This study tested whether using the Physitrack app at home helps handball players follow their exercise routines and improve their jumping ability. Twenty-eight healthy adult male handball players were assigned to one of two eight-week home exercise programs through the app. Rese…

This study checked if a generic version of tenofovir disoproxil fumarate (a drug used for HIV and hepatitis B) works the same as the brand-name drug Viread. Forty-seven healthy Chinese adults took both versions under fasting and fed conditions. The goal was to see if the generic …

This early-stage study tested whether giving regular insulin as nose drops is safe and tolerable in 24 healthy adults. Researchers aimed to find the highest dose that could be given without causing dangerously low blood sugar. The study was completed and focused on safety, not on…

This study looked at how sore calf muscles (DOMS) affect other muscles in the back and legs of 14 healthy young adults. Researchers measured muscle stiffness, strength, balance, and endurance before and after exercise. The goal is to help people understand how one sore spot can i…

This study looked at how the body processes a single dose of the drug cenerimod in people with severe kidney impairment compared to healthy volunteers. A total of 16 adults took part. The goal was to measure drug levels and safety, not to treat any disease.

This study looked at how healthy men absorb, break down, and eliminate a single dose of the drug KBP-5074. Seven men took a radioactive-labeled version of the drug so researchers could track it in blood, urine, and stool. The goal was to understand the drug's metabolism and how i…

This study looked at how the body processes a drug called MK-1084 when taken alone or with two other common drugs (itraconazole and phenytoin) in 28 healthy adults. The goal was to measure drug levels in the blood to understand potential interactions. This is a Phase 1 trial, mea…

This early-stage study tested a new oral drug, YUQ-A1007, in 47 healthy adults to see if it is safe and how the body processes it. The drug is designed to treat inflammatory bowel disease (IBD) by targeting the gut. Since this is the first time the drug is given to humans, the ma…

This study looked at how the drug carbamazepine changes the way another drug, evobrutinib, moves through the body. Fourteen healthy adults took both drugs in a specific order, and researchers measured drug levels in their blood. The goal was to understand the interaction, not to …

This study tested a placebo solution that feels like a real nerve block but provides no pain relief. Seventeen healthy volunteers received injections to see if they could tell the difference. The goal is to create a convincing placebo so future studies can more accurately measure…

This study looked at how two common stomach acid reducers (famotidine and rabeprazole) affect the levels of the drug nirogacestat in the blood. Twenty-four healthy men took nirogacestat alone and with each acid reducer. The goal was to see if these stomach medications change how …

This small pilot study looked at how certain drinks change appetite-related hormones after a meal in 12 healthy adults. Participants were between 20 and 50 years old with a normal body weight. The goal was simply to measure hormone levels and hunger ratings, not to treat or cure …

This study looked at how the brain helps people move skillfully with their left hand after a right-arm nerve injury. Researchers used MRI scans to compare brain activity in people with and without nerve damage. The goal was to understand brain adaptation, not to test a treatment.

This study looked at how a new drug (DA-5222) is absorbed by the body when taken alone versus when its three components are taken together. Forty healthy adults each received both treatments in a random order, and researchers measured drug levels in the blood. The goal was purely…

This study measured lung function in 2000 healthy Polish children and teens aged 3-18 to establish what 'normal' breathing looks like. The goal is to create reference charts that doctors can use to better diagnose and monitor lung diseases like asthma. Participants were all healt…

This study looked at how different manufacturing batches of the drug evobrutinib are absorbed by the body in 28 healthy adults. The main goal was to compare drug levels and safety between batches. Participants took a single dose under fasting conditions, and researchers measured …

This study looked at whether a massage technique based on the tensegrity principle (how parts of the body work together as a connected system) can improve muscle function. Fifty-four healthy men aged 19-24 received either the special massage or no treatment. Researchers measured …

This study tested a new, stronger version of the drug RPH-104 in 130 healthy adults aged 18-45. The goal was to see how safe it is, how the body processes it, and whether it triggers an immune response. No treatment was given for any disease, so this study helps gather important …

This study looked at how having low blood sugar (hypoglycemia) affects the body's automatic nervous system, which controls things like heart rate and blood pressure. Researchers tested 28 healthy adults to see if a drug called spironolactone could block these effects. The goal wa…

This early-stage study looked at how safe a new drug called epaminurad is and how it moves through the body. It involved 34 healthy adults who took a single dose of the drug while fasting. The goal was to measure drug levels in the blood, not to treat any disease.

This study looked at whether showing people their blood sugar levels in real time changes how they think about a milk drink with mulberry leaf extract. 170 healthy or prediabetic adults aged 45-75 took part. The goal was to see if seeing the drink's effect on glucose made people …

This study tested a 6-week training program called the 5-Line Principle of Balanced Intensity Training (BPIT) in 23 healthy adults who already exercise regularly. The program uses five levels of exercise intensity, from low-impact ground moves to high-impact jumps. Researchers me…

This study looked at how muscle strength relates to balance in 72 people, comparing healthy individuals to those with chronic ankle instability or ACL knee injuries. Researchers measured static and dynamic balance using a special platform. The goal was to understand how lower lim…

This study looked at how the way a baby is born (C-section or vaginal delivery) changes the nutrients in breast milk. Researchers analyzed milk from 250 healthy mothers in China to compare levels of sugars, fats, and proteins. The goal was to understand these differences, not to …

This study looked at whether taking itraconazole changes how much of another drug, BI 764198, stays in the blood. Fourteen healthy men took both medicines at different times, and researchers measured drug levels. The goal was to understand how these drugs interact, which helps do…

This study looked at how special window films, used to make homes more energy-efficient, affect people's thinking, perception, and health. 41 healthy adults aged 18-40 took cognitive tests and reported their comfort levels. The goal was to see if these quick and cheap home upgrad…

This early-stage study tested a new drug called SUVN-I6107 in 64 healthy adults to see if it is safe and how the body processes it. Participants received either the drug or a placebo as a single dose or multiple doses. Researchers also checked for changes in brain activity using …

This study tested whether different smells (like city or nature scents) affect how much people eat in a virtual reality outdoor café. 25 healthy young adults (ages 18-29) took part. The goal was to learn how urban design and scents might help people make healthier food choices.

This study looked at the food habits, dietary practices, and food preferences of 200 older adults aged 60 and above living in Singapore. Researchers interviewed participants from different ethnic backgrounds to better understand their nutritional needs. The goal was to gather inf…

This study looked at how eating different colored carrots (red, purple-red, and purple) affects the body's ability to absorb beneficial plant pigments called carotenoids and anthocyanins. Twelve healthy adults drank carrot juice from each variety over several weeks, and researche…

This study tested a new mobile health program designed to help young Latina women in Alabama learn about sexual health and feel more confident accessing healthcare. 25 women aged 16-21 who hadn't had a checkup in over a year took part. The program used culturally tailored educati…

This study looked at how certain foods (resistant starch and sodium butyrate) affect compounds made by gut bacteria and how those compounds might influence heart and lung reflexes. Fourteen healthy adults took each supplement for four weeks. The goal was to understand the connect…

This study tested a wearable device that buzzes when surgical residents slouch during operations. Twelve residents wore the device to see if it helped them stay upright and reduced muscle pain. The goal is to prevent long-term injuries and help surgeons have longer, healthier car…

This study checked if a Philips pulse oximeter, using Masimo sensors, accurately measures blood oxygen levels in people with different skin colors. 70 healthy adults took part. The goal was to make sure the device works well for everyone, not just those with lighter skin.

This study looked at how a drug called BI 655130 enters the body when injected in different places (belly vs. thigh) and in different doses. It involved 48 healthy adults aged 18 to 50. The goal was to understand the drug's behavior, not to treat any disease.

This study tested a low-powered microwave imaging system on 50 healthy women aged 18-74 to see if it could measure electrical properties of breast tissue. The goal was to find out if these properties relate to breast density seen on mammograms. Each participant had both breasts s…

This early-stage study tested the safety and tolerability of a new drug called BI 1569912 in 56 healthy Japanese men. Participants received either a single dose or multiple doses of the drug or a placebo. The main goal was to check for side effects and measure how the drug behave…

This study looked at how the drug calderasib enters the blood when taken as two different tablet types, and whether food changes its absorption. Fifty-two healthy adults participated. The goal was to gather information, not to treat any disease.

This study looked at how Parkinson's disease changes the brain's ability to sense time. Researchers measured eye movements in 40 people (patients and healthy volunteers) while they performed timing tasks. Patients were tested both on and off their usual medication to see how dopa…

This early-stage study tested the safety and how the body processes KBP-5074 in 26 healthy adults and people with mild to moderate kidney impairment. Researchers measured side effects and drug levels in the blood to help design future larger studies. No treatment was given; the g…

This study looked at how squatting at different depths (partial, parallel, full) changes leg muscle activity and jump performance. Fourteen healthy, experienced exercisers did squats at each depth while their muscle signals and jump height were measured. The goal was to understan…

This study tested a new high-density EEG method to map brain areas involved in movement, sensation, language, emotion, and thinking. It included 122 people with epilepsy, brain tumors, and healthy volunteers. The goal was to improve understanding of brain function and seizure act…

This study looked at how a new drug called LY4065967 is absorbed, broken down, and removed from the body in 16 healthy men. Participants took a single dose with a tiny radioactive label so scientists could track it in blood, urine, and stool. The goal was purely to understand the…

This study looked at whether a supplement called MIB-626 (a form of vitamin B3) could improve physical fitness, muscle energy, and brain function in healthy, highly active adults aged 19 to 40. Participants took either the supplement or a placebo twice daily for 10 weeks, with so…

This study looked at why some people feel a sharp increase in pain when a numbing injection (nerve block) wears off after surgery. Researchers gave 40 healthy adults a nerve block in one arm and measured their pain sensitivity as the numbness faded. The goal was to see if the ner…

This study looked at how drinking coffee or tea at the same time as a new drug called enlicitide changes the amount of drug in the blood. 60 healthy adults took part, and researchers compared drug levels when taken with coffee, tea, or water. The goal is to see if these common dr…

This study gave 5 healthy adults a single dose of the drug PF-07304814 mixed with a tiny radioactive tracer to see how the body breaks it down and gets rid of it. Researchers measured the drug and its byproducts in blood, urine, and stool over time. The goal was to understand the…

This early-stage study tested a single dose of BI 1015550 in 24 healthy Chinese adults to see how the drug is processed by the body and whether it is safe. Participants were closely monitored for side effects and drug levels in their blood. The study is complete and provides basi…

This study checked how well a computer-controlled treadmill can create precise balance disturbances. Twelve healthy adults walked on the treadmill while sensors measured the treadmill's movements. The goal was to see if the treadmill's actual movements matched what it was command…

This study looked at how different versions of the drug bimagrumab, given alone or together with tirzepatide, behave in the body. It involved 125 healthy adults and lasted about 4.5 months. The main goal was to measure drug levels in the blood, not to treat any disease.

This study looked at how a new drug called BI 1810631 is absorbed, broken down, and removed from the body in 15 healthy men. Part A measured how much of the drug was recovered in urine and stool. Part B compared how well the tablet form works versus a tiny IV dose. The goal was t…

This study looked at whether drinking dairy products after exercise helps bone turnover and reduces inflammation better than a sugary drink or water. Twenty healthy young adults (ages 18-30) took part. Researchers measured bone markers and immune responses in the blood after exer…

This study tested a training program for daycare providers to improve how they interact with children. 200 providers took part, with some getting training and others not. The goal was to see if the training helps children develop better social, emotional, and language skills.

This study tested a virtual reality (VR) afterschool program for children ages 9 to 17. The goal was to see if kids would use and enjoy the VR system, and to measure how many stayed with the program. 32 children from a community program took part, and researchers tracked their st…

This study followed 600 healthy infants from 2 months to 6 years old to see how being fed mostly breast milk, milk-based formula, or soy-based formula affects their growth, body composition, and brain function. Researchers measured physical development and thinking skills over ti…

This study looked at whether delgocitinib, taken as a capsule, changes heart rhythms in 40 healthy adults. Researchers compared the drug to a placebo using detailed ECG recordings. The goal was to check for any heart-related safety issues, not to treat a disease.

This study tested a computer model, called a digital twin, to see if it could predict how muscles get stronger and bigger from strength training. 23 healthy adults aged 20-40 with at least a year of training experience did an 8-week program. The goal was to improve training guide…

This study tested a special 3D-printed pill that people swallow to collect bacteria from the gut. Ten healthy adults took the pill to see if it could safely grab samples from the small intestine and compare them to stool samples. The goal was to check if the pill works well and c…

This study looked at how different levels of simulator movement affect pilot performance when using a mixed-reality headset. Thirteen healthy adults completed flight tasks in a simulator with no motion, small motion, or full motion. The goal was to measure how accurately and quic…

This early-stage study tested the safety of a new drug, MH-001, in 58 healthy adults. Participants received either the drug or a placebo to check for side effects and how the drug moves through the body. The goal was to gather safety information, not to treat any disease.

This study looked at how imlunestrant affects the body's processing of other drugs like repaglinide, omeprazole, and digoxin in healthy women who cannot become pregnant. It also tested how another drug, quinidine, changes imlunestrant levels. The goal was to understand safety and…

This early-stage study tested whether delgocitinib cream, a treatment for skin conditions like eczema, can cause skin irritation when exposed to light. Thirty-five healthy adults received a single application of the cream and a placebo on different skin spots, then were exposed t…

This study looked at how the drug MK-8527, which may be used to prevent HIV, passes into breast milk. Thirteen healthy mothers who were at least 6 weeks postpartum took a single dose. Researchers measured drug levels in their breast milk, blood, and whole blood over 120 hours to …

This study checked whether two different pill versions of the drug nerandomilast are processed the same way in the body. 64 healthy adults each took a single dose of both versions at different times. The goal was to see if the new version works like the one used in later-stage st…

This study looks at how a common antifungal drug (itraconazole) changes the way the body handles an experimental drug called TD-1211. Twenty healthy adults aged 18 to 50 will take a single dose of TD-1211 with and without itraconazole. Researchers will measure drug levels in the …

This study looked at how healthy adults digest and use two forms of milk protein: intact casein and pre-digested (hydrolyzed) casein. 26 healthy volunteers with a BMI between 18 and 25 took part. The goal was to measure how much protein the body actually absorbs and how the body …

This study enrolled 26 healthy adults to see how different airflow settings on two new high-flow nasal cannula (HFNC) devices affect lung aeration. Participants tried various flow rates while their lung volume and comfort were measured. The goal was to understand which settings w…

This early-stage study involved 8 healthy adults to see how the body absorbs and processes zolmitriptan when taken as a pill versus a nasal spray. Researchers measured heart rate, blood pressure, and drug levels in the blood over 24 hours. The goal was to build a model that predi…

This study looked at how the antibiotic erythromycin changes the way a new drug, BI 1291583, stays in the body. Twenty healthy adults took both drugs to measure drug levels. The goal was to gather information, not to treat any disease.

This study checked the immune status of 1,024 police officers in Bern, Switzerland, against COVID-19 over one year. Researchers looked at how work and home life affected infection risk and how often protective gear was used. The goal was to learn more about virus spread in this g…

This study surveyed over 2,000 healthy adults from different racial and ethnic groups to learn how well they understand epigenetics—how environment and behaviors can turn genes on or off. The goal was to find better ways to explain epigenetics so people can make informed decision…

This early-stage study tested an experimental drug called BI 655130 in 36 healthy adults. The main goal was to see how well the drug is absorbed when given as a shot under the skin compared to through an IV. Researchers also checked safety and how the drug behaves in the body. No…

This study tested whether an experimental HIV medicine called ulonivirine (MK-8507) affects heart rhythm. 62 healthy adults received the drug or a placebo, and researchers measured changes in their heart's electrical activity. The goal was to ensure the drug is safe for the heart…

This study tested a new quick-dissolve tablet (M107 ODT) containing the drug lobeglitazone in 21 healthy adults. Researchers compared how the body absorbs and processes the drug when taken with or without food, and how it compares to the standard Duvie® tablet. The goal was to ga…

This study compared a generic numbing cream (lidocaine and prilocaine) to the brand-name EMLA cream in 40 healthy adults. The goal was to see if the generic version enters the bloodstream at the same rate and amount as the brand-name cream. Participants received both creams at di…

This early-stage study tested how a long-acting HIV medication (rilpivirine, given alone or with cabotegravir) moves through the body after a single injection under the skin. 126 healthy adults took part to check safety and drug levels. The goal was not to treat disease, but to g…

This study looked at how two types of poor sleep—waking up often or having broken sleep—change the way a painkiller works in the brain. Healthy adults aged 18-48 took part in sleep experiments and then received a study drug to measure pain relief and addiction risk. The goal was …

This study used a special MRI technique with a harmless helium gas to measure how fast air moves through the windpipe. Researchers scanned 24 volunteers, including healthy people and those with COPD or constrictive bronchitis. The goal was to collect real data to improve computer…

This study looked at how taking VRN110755 with food or a common heartburn drug (rabeprazole) changes its levels in the blood. Twenty-five healthy adults took the drug under different conditions. The goal was to gather information, not to treat any disease.

This early-stage study tested the safety and how the body processes an inhaled drug called DBM-1152A in 20 healthy Chinese adults. Participants inhaled the drug or a placebo once daily for 7 days. The goal was to check for side effects and measure drug levels in the blood, not to…

This study looked at whether taking the drug BI 425809 with food changes how much of it gets into the blood. Sixteen healthy adults took the drug once with a meal and once on an empty stomach. The results will help doctors know if the drug should be taken with or without food.

This study tested whether a drug that lowers heart rate (ivabradine) can improve the flexibility of arteries in healthy people. 30 volunteers aged 25-65 with a resting heart rate of 70 or higher took either the drug or a placebo for 8 days. Researchers measured artery stiffness a…

This study tested 35 adults with ankle arthritis or lower limb injury to see how different cuff designs on carbon fiber leg braces affect comfort, walking mechanics, and user preference. Participants walked with several cuff styles while researchers measured foot pressure, pain, …

This study looked at how two different pill versions of a new drug, BI 1810631, are absorbed in the body. It involved 13 healthy men who took single doses of each version, and also tested how food and a common stomach acid medicine (rabeprazole) affected absorption. The goal was …

This early-stage study tested a new drug called BI 3006337 in 36 healthy Japanese men to see if it is safe and how the body handles it. Participants received either a single shot or multiple shots over 6 weeks. The goal was to gather safety and drug-level data, not to treat any d…

This study tested two different ways to give the experimental drug remternetug: an auto-injector (like an EpiPen) and a traditional prefilled syringe. The goal was to see how much of the drug gets into the bloodstream and how fast the body clears it. 72 healthy adults took part, …

This pilot study tested whether the BCG vaccine (used for tuberculosis) can change certain markers in the blood and spinal fluid of healthy older adults. Researchers measured immune responses and Alzheimer's-related proteins in 20 participants aged 55-80. The goal was to gather e…

This study looked at arm function and oxygen use in 60 women — some who had breast cancer and some who were healthy. Researchers measured how well the arms work during exercise and how muscles use oxygen. The goal was to understand if breast cancer survivors have reduced arm capa…

This study looked at how iron supplements change the way the body handles a drug called MT-6548. It involved 61 healthy Japanese men who took the drug with and without iron. The goal was to measure drug levels in the blood, not to treat any disease.

This study looked at how fasting changes the way your body and brain use energy. Researchers studied 12 healthy adults to understand the switch from using sugar to using fat for fuel. The goal was to learn more about the biological processes behind fasting's potential health bene…

This study looked at 111 healthy nursing students to see if their natural sleep-wake patterns (chronotype) influenced their motivation and test scores when taught using a flipped learning approach. Researchers measured chronotype with a questionnaire and compared motivation and e…

This study looked at healthy men to see if the proteins in their saliva affect how bitter they find caffeine. Participants tasted caffeine and gave saliva samples for analysis. The goal was to understand natural differences in taste, not to test any treatment.

This study looked at whether taking monosodium glutamate (MSG) regularly changes how fast the stomach empties and how the body uses protein from food. Thirteen healthy adults with a BMI between 23 and 28 took part. The goal was to understand how MSG might affect digestion, not to…

This study looked at how the experimental drug BI 3000202 is absorbed, broken down, and removed from the body in 12 healthy adults. In one part, participants took the drug as a liquid to measure how much leaves in urine and stool. In another part, they took a tablet and a tiny in…

This study looked at how warm-up programs and shoe type affect movement patterns that can lead to injury in youth soccer players. 64 players aged 13-17 took part. Researchers tested a shortened FIFA11+ warm-up versus a standard one, and compared female-specific cleats to unisex c…

This study looked at 24 national-level male rowers to see how their motivation and body chemistry change during intense exercise. Participants completed a motivation questionnaire, performed a 6000-meter rowing test, and gave blood samples before, right after, and one hour after …

This study looked at how different exercise intensities affect a brain chemical called BDNF, which helps brain cells grow and stay healthy. Twelve healthy adults aged 18-25 did three types of exercise: high-intensity intervals, moderate continuous running, and light continuous ru…

This early-stage study looked at how well a medicated cream (Metvixia) gets into the skin after using different mechanical techniques like sanding or poking. Ten healthy volunteers had small test areas on their backs treated with various methods. The goal was simply to measure ho…

This early-stage study tested a new drug called BI 1015550 in 16 healthy Japanese men to see if it is safe and how the body handles it. Participants received a single rising dose of the drug or a placebo. The goal was to check for side effects and measure drug levels in the blood…

This study looked at how taking carbamazepine (a seizure medicine) changes the way the body processes nerandomilast, an experimental drug. Sixteen healthy men took both drugs, and researchers measured drug levels in their blood. The goal was to gather safety and interaction data,…

This study looked at how two medical devices—one using pressure waves and the other using mild electrical stimulation—temporarily change blood flow in the lower leg. Twenty healthy adults took part. The goal was to measure blood flow changes, not to treat any disease.

This study tested whether a supplement made from cornelian cherry (a fruit) could improve heart and blood vessel function in 18 healthy amateur long-distance runners over 45 years old. Participants took either the cherry supplement or a placebo for four weeks, then switched after…

This study tested a wearable device that uses electrical stimulation to help stroke survivors improve their walking. Researchers first recorded muscle activity from healthy volunteers to understand normal walking patterns. Then, stroke survivors used the device for about a month …

This study looked at whether eating a diet with inulin (a type of fiber) for 7 days changes how many calories the body burns at rest and after meals. It included 61 healthy or overweight adults. The goal was to understand how this fiber affects energy use, not to treat a disease.

This study tested whether a dietary supplement containing oleoylethanolamide, ginger, and lavender oil can change gene activity and blood markers in healthy adults. 92 participants took the supplement daily for 12 weeks and provided blood and urine samples. The goal was to unders…

This early-stage study looked at how the experimental drug DA-1229_01 is processed by the body when taken on an empty stomach. 42 healthy adults participated to measure drug levels in the blood and check for any safety issues. The goal was to gather basic information, not to trea…

This study tested whether two different versions of the drug nerandomilast are absorbed the same way in the body. It involved 64 healthy adults who took a single dose of each version on separate days. The goal was to confirm the new version works like the one used in later-stage …

This study looked at how eating dinner early or late affects metabolism in healthy adults aged 18-30. Researchers timed meals based on each person's internal body clock. Participants ate either before or after their natural melatonin rise, and blood samples were taken to measure …

This study looked at how a single session of strength training with a metronome (paced beats) affects the brain and nerves that control muscles. Thirty healthy men aged 18 to 40 did different types of paced exercises. The goal was to see if adding natural movement variability spe…

This study tested a new medicine called PF-07264660 in 12 healthy Chinese adults to see if it is safe and how the body processes it. Participants received a single IV dose, with three-quarters getting the real medicine and one-quarter getting a placebo. The study lasted up to 181…

This study looked at how immune cells in the lungs respond to a TB protein called PPD. Seventeen adults—some with latent TB and some without—received PPD directly into their lungs during a bronchoscopy. Researchers then collected lung cells and used scans to measure immune activi…

This early-stage study tested the safety and how the body processes two experimental drugs (CTL0201 and CTL0202) given together or alone. Forty healthy adults aged 19 to 55 took a single dose and were monitored. The goal was to gather safety information, not to treat any disease.

This study looked at how the brain combines information from faces and voices to decide a person's gender. 38 healthy adults underwent brain scans while performing a gender classification task. The goal was to understand which brain areas are involved and how visual and auditory …

This study looked at how the antifungal itraconazole changes the amount of an experimental drug (BI 1815368) in the blood of 14 healthy men. Participants took the experimental drug alone and later with itraconazole to compare drug levels. The goal was to understand if dose adjust…

This study looked at whether DMT, a psychedelic drug, can reduce pain in 17 healthy adults. Researchers used mild electric shocks to cause pain and compared DMT to ketamine and a placebo. The goal was to see if DMT could be a new option for treating pain conditions like chronic p…

This early-stage study tested the safety and how the body handles a new drug called D-2570 in 100 healthy adults aged 18 to 45. Participants received either the drug or a placebo, and researchers monitored side effects, vital signs, and drug levels in the blood. The goal was to g…

This study looked at how two HIV drugs, azvudine and aluvia, interact in the bodies of 15 healthy adults. Participants took the drugs in different orders over three cycles, with blood tests to measure drug levels and safety. The goal was to gather information for future HIV treat…

This study looked at how cannabidiol (CBD) is absorbed and processed in 24 healthy adults. Researchers measured CBD levels in blood and urine to understand its safety and how the body handles it. The goal was to gather basic information, not to treat any disease.

This early-stage study tested the safety and how the body processes two forms of the experimental drug solrikitug in 32 healthy adults, both Japanese and non-Japanese. Participants received the drug under the skin and were monitored for side effects and drug levels. Since this st…

This study looked at how healthcare practitioners move their hands and fingers when inserting a peripheral IV catheter. Researchers measured the forces applied to the skin and veins, as well as needle angles and finger pressure. The goal is to use this data to create more realist…

This study looked at how nabilone, a cannabis-like drug, changes a brain enzyme called FAAH in 10 healthy adults. Participants took nabilone for one week and had brain scans before and after. The goal was to understand how the drug works in the brain, not to treat any disease.

This study looked at how the brain recovers after people stop using cannabis. Researchers used brain scans and EEG to measure changes in brain receptors and rhythms over four weeks of abstinence. The study included 162 people who were either cannabis-dependent or healthy non-user…

This study collected brain PET scans from 41 healthy adults aged 20-65 to create a reference database. Doctors can compare these normal scans to those of epilepsy patients to more precisely locate where seizures start, helping guide surgery when medications fail. The goal is to i…

This study measured normal breathing resistance in 122 healthy, non-smoking adults using a technique that requires little cooperation. The goal was to establish reference values for adults, similar to those already used in children. This method could help evaluate lung function i…

This study looked at how caffeine affects anxiety, decision-making, and body awareness in 42 people—some with panic disorder and some healthy. Participants took either caffeine or a placebo and had their brain activity scanned using a powerful MRI machine. The goal was to underst…

This study looked at whether letting people choose their own mindfulness exercise (focusing on breath or sounds) leads to better results than being assigned one randomly. Over 240 healthy adults in the UK took part. The goal was to see if choice affects mindfulness levels and the…

This study tested a new way to measure different types of fat in the blood after eating. Fourteen healthy adults ate a test meal, and researchers collected blood samples to see how the fats were broken down. The goal was to see if a special MRI technique (NMR) could accurately me…

This study tested whether delgocitinib cream, applied to the skin and then exposed to UV light, can cause a photoallergic reaction. Sixty healthy adults aged 18-64 with fair to medium skin types took part. Researchers compared skin reactions between areas with the cream and areas…

This study looked at how a common seizure drug, carbamazepine, changes the amount of mirdametinib in the blood. 36 healthy adults took both drugs to see how the body processes them together. The goal was to understand potential drug interactions, not to treat any disease.

This study looked at how carbon dioxide (CO2) might cause trouble with thinking or memory. Researchers measured immune cell activity in blood samples from 27 healthy adults after CO2 exposure. The goal was to understand the biological process behind CO2-related cognitive impairme…

This study tested a robotic platform that uses motion cameras to keep a person's head still in real time. Twenty healthy volunteers participated, and no radiation was used. The goal was to collect motion data to help develop better head stabilization methods for future brain radi…

This study looked at the types of immune cells in the blood of 40 healthy Danish women aged 18-41. The goal was to create a reference for future studies on how the immune system affects diseases in women of reproductive age. No treatment or intervention was given.

This early-stage study tested the safety and how the body handles a new drug called BI 425809 in 96 healthy young and elderly volunteers. Participants took the drug as tablets once daily for 12 days, and researchers also compared taking it in the morning versus evening. The goal …

This study looked at how the heart's muscle stiffness (fibrosis) changes as people age normally. Researchers used MRI scans and blood tests to measure fibrosis in 74 healthy adults. The goal was to better understand age-related changes in heart function, not to treat any disease.

This study tested how accurately the ProSomnus RPMO2 device measures oxygen levels and heart rate. Twelve healthy adults wore the device while their oxygen levels were temporarily lowered in a controlled setting. The results help confirm if the device works well for future use.

This study looked at how the body absorbs two different versions of the experimental drug BI 456906. Sixteen healthy adults each received a single injection of both formulas at different times. The goal was to compare the two formulas, not to treat any disease.

This study looked at whether a brief calf muscle release technique could immediately change how far healthy adults can bend their neck forward and backward. 90 people aged 18-40 took part. Researchers measured neck motion before and right after the calf treatment to see any short…

This study looked at how healthy adults absorb nutrients from two different blueberry varieties and a blueberry-enriched protein bar. Over three months, 29 participants ate each test meal and provided blood and urine samples. The goal was to see if processed blueberry products of…

This study checked if a new system called AuReha can measure arm and shoulder movements as accurately as the standard tool (a goniometer). It involved 96 healthy adults who had no arm or trunk movement problems. The goal was to see if AuReha could be a reliable alternative for fu…

This study looked at how food and certain drugs (omeprazole, itraconazole, carbamazepine) affect the amount of a new medicine called LY3484356 in the blood of healthy women who cannot become pregnant. The goal was to understand how the body processes the drug, not to treat any di…

This study looked at how well two different tablet forms of the drug miricorilant are absorbed by the body. It involved 18 healthy adults who took the drug in different forms and had their blood levels measured. The goal was to compare the formulations, not to treat any disease.

This study looked at how well two different autoinjectors deliver the drug mirikizumab into the bloodstream of healthy people. About 500 healthy adults received a single injection under the skin using either a standard 1-mL autoinjector or a newer 2-mL version. The goal was to se…

This study looked at how moderate and severe liver impairment changes the way the body handles a single dose of the drug palovarotene. Researchers compared 31 participants with liver problems to healthy volunteers. The goal was to understand safety and drug levels in the blood, n…

This study looked at how the drug BI 1015550 is absorbed in people with and without kidney problems. 26 adults took a single tablet, and researchers measured drug levels in their blood over two weeks. The goal was to see if kidney issues change how the drug behaves, which helps d…

This early-stage study tested a single injection of a new drug called BI 3006337 in 80 healthy men. The main goal was to check if the drug is safe and how the body processes it. No treatment for any disease was given; this was purely a safety and drug-level study.

This study looked at how the experimental drug LY4064809 is absorbed and removed from the body in 10 healthy Chinese adults. Participants took the drug by mouth and were monitored for about 21 days. The goal was to measure drug levels in the blood and check for any safety issues.…

This early-stage study tested a new drug called BI 3034701 in 125 healthy men and people with overweight or obesity. The main goal was to see if different doses are safe and how the drug enters the blood. Participants received either the drug or a placebo as an injection under th…