HEALTHY

This study tested a single-shot vaccine designed to protect against two common respiratory viruses: RSV and human metapneumovirus (hMPV). It involved 264 healthy adults aged 60 to 85. The main goals were to check the vaccine's safety and see how well it triggered an immune respon…

This study tested a new version of an experimental vaccine called V118 in healthy adults. The main goal was to check how safe it was and how well people's bodies responded to it. Researchers gave the vaccine to 65 volunteers and closely monitored them for any side effects.

This study tested a new vaccine called V330 designed to protect against norovirus, a common stomach bug. Researchers gave the vaccine to 245 healthy adults aged 18-49 and 60-79 to check if it's safe and if it triggers the body to produce protective antibodies. This was an early s…

This study tested whether a new drug called ciraparantag could safely and effectively reverse the effects of the blood thinner rivaroxaban. Healthy volunteers aged 50-75 took rivaroxaban for three days, then received either ciraparantag or a placebo to see how quickly their blood…

This study tested a new drug called ciraparantag to see if it could quickly reverse the effects of a common blood thinner (apixaban). The goal was to help control dangerous bleeding in emergencies. Healthy volunteers took the blood thinner and then received either the reversal dr…

This study tested whether drinking a cocoa beverage rich in natural plant compounds called flavanols could help protect blood vessel function during prolonged sitting. Twenty healthy adults aged 65+ drank either a high-flavanol or low-flavanol cocoa drink before sitting for two h…

This early-stage study tested a new oral drug called LY3549492 in 92 Japanese adults, including those with type 2 diabetes and healthy volunteers. The main goal was to check the drug's safety, side effects, and how the body absorbs and processes it. Researchers also looked for ea…

This was an early-stage study to check the safety and basic effects of a new oral drug, RAY1225, which is being developed for weight management. It involved 68 healthy and obese adults in China. The main goal was to see how the body processes the drug and to monitor for any side …

This first-in-human study tested the safety and how the body processes CAN10, a new antibody being developed for plaque psoriasis. The trial involved 80 healthy volunteers and people with mild to moderate psoriasis, testing single and repeated doses. Researchers monitored side ef…

This study tested a new imaging technique called electrical impedance tomography (EIT) to see if it can monitor lung changes in children and young adults with cystic fibrosis. Researchers compared EIT to standard CT scans to see if it could detect areas of trapped air and lung da…

This study tested if a special measuring cup that automatically records urine volume gives more accurate results for bladder diaries than the usual method of just looking and guessing. Researchers compared the two methods over three days in 187 adult women, some with urinary symp…

This study tested how well a new wristwatch device measures heart rate and detects atrial fibrillation (an irregular heartbeat). Researchers compared the device's readings to standard medical equipment in 365 people, including those with and without heart rhythm problems. The goa…

This study tested a new laboratory method for measuring how well blood platelets work in people taking common blood-thinning medications like aspirin and clopidogrel. Researchers compared this new test against the current standard method in 112 healthy volunteers, including some …

This study tested how well a new model of pulse oximeter (a finger clip that measures blood oxygen) works on people with different skin tones. It involved 70 healthy adults to see if the device's readings were accurate and reliable for everyone, regardless of skin pigmentation. T…

This study tested an experimental antibody injection, called G03-52-01, to see if it could safely protect healthy adults from illness caused by botulinum toxin. About 622 participants received either the antibody or a placebo shot to compare safety and measure the body's protecti…

This study tested whether using a mouthwash containing cetylpyridinium chloride and zinc after brushing could reduce the occurrence of cold and flu symptoms. 150 healthy adults were randomly assigned to either use the mouthwash twice daily or just brush their teeth normally for 9…

This early study tested insulin given as nose drops in 24 healthy volunteers to find the highest safe dose. The goal is to see if giving insulin through the nose right after a person's heart stops could protect their brain from injury. Researchers measured blood sugar and other s…

This study tested whether a personalized smartphone app and wearable device could help older adults adopt healthier lifestyles. Researchers compared the app, which provided coaching on physical activity and nutrition, to standard health education materials. They enrolled 237 heal…

This study looked at ways to prevent serious knee injuries in young soccer players. Researchers tested if a shorter, 12-week warm-up program was better than a standard one at improving safe movement during quick turns. They also tested if soccer cleats designed specifically for f…

This study tested whether a daily pill could be a safe and effective form of birth control for men. Researchers gave 92 healthy men different doses of an experimental drug, either alone or combined with another hormone, for 12 weeks. The main goal was to see if the pill could rel…

This study tested whether a daily drink made from freeze-dried watercress could help the body remove harmful environmental chemicals linked to cancer. It involved 300 healthy adults, who took either the watercress drink or a placebo for two weeks. The research focused on people w…

This early-stage study tested whether a very high dose of a new monthly oral pill for preventing HIV infection could affect heart rhythm. It involved 42 healthy adult volunteers to check for safety signals, particularly any changes to the electrical activity of the heart. The mai…

This study tested whether a 6-week exercise program delivered through a smartphone app could help high school athletes move better and reduce their risk of injury. Researchers measured how often 19 athletes used the app and checked their agility and movement quality before and af…

This study tested whether a special 12-week warm-up program could help prevent injuries in young male volleyball players. Twenty-four players aged 15-17 were split into two groups: one used the new warm-up, and the other used their usual routine. Researchers measured their balanc…

This study tested a new mobile app designed to help young Latina women in Alabama learn about sexual health and how to access healthcare services. The app created a private, virtual space with educational modules and a connection to peer guides. The goal was to see if this approa…

This early-stage study tested the safety of a combination of two lab-made antibodies (casirivimab+imdevimab) against COVID-19. It involved 45 healthy or medically stable adult volunteers who received the antibodies either as an injection under the skin or through an IV drip. The …

This study tested whether teaching relaxation exercises to first-year nursing students could help them manage stress before starting clinical work. Researchers compared 80 students, with half practicing guided relaxation techniques twice a week for a month. They measured changes …

This small, completed pilot study explored whether two simple workplace changes could help night shift nurses. Researchers tested if giving nurses access to a quiet nap/relaxation room and special glasses that block certain light could improve their health, sleep, and reduce feel…

This study tested different methods to reduce pain from dental injections in children. Researchers compared cold sprays, numbing gels, and regular numbing sprays on 100 children aged 7-10 during dental treatments. They measured pain levels, anxiety, and physical responses to find…

This study tested the safety and effectiveness of an anti-aging face cream. It involved 44 women, aged 45 to 65, who had sensitive skin and deep wrinkles. Participants used the cream for 57 days while researchers checked for skin irritation and measured changes in wrinkles, smoot…

This study tested if a small wearable device could help surgical residents avoid poor posture and reduce pain. The device gently vibrates to remind the wearer to stand up straight during laparoscopic surgeries. Researchers measured how much time residents spent in good posture an…

This study tested a wearable device that delivers gentle electrical stimulation to multiple leg muscles to help chronic stroke survivors improve their walking. Researchers first measured normal muscle patterns in healthy participants, then used that information to guide month-lon…

This study tested whether a supplement made from olives (OliPhenolia®) could help healthy adults recover faster from exercise. Researchers gave 18 participants either the supplement or a placebo before and after a tough workout. They measured blood markers of inflammation and mus…

This study tested whether a small vibrating device called DigiVibe could reduce pain during common needle procedures like shots and fingersticks. It involved 20 healthy adults who reported a fear or dislike of needles. Each participant received injections and fingersticks both wi…

This study tested whether Swedish massage or handheld percussion therapy (like a massage gun) works better to help muscles recover after hard exercise. Researchers measured muscle soreness, stiffness, and jump performance in 24 healthy, active young adults. The goal was to see wh…

This study tested whether listening to calming music before and after a common heart procedure (coronary angiography) could help patients feel better. Researchers compared 210 patients, with half listening to specially selected music and half not. They measured pain, anxiety, vit…

This study tested whether a digestive enzyme supplement helps people digest heavy meals better and reduces symptoms like bloating and gas. Researchers gave 24 healthy adults either the enzyme pill or a placebo before they ate a high-fat, high-protein meal. They measured how well …

This study tested whether taking a Rhodiola rosea supplement for 28 days could help basketball players perform better and feel less tired during simulated games. Researchers gave the supplement or a placebo to 48 healthy, professional male players. They measured game completion t…

This small pilot study tested a new workout method called Balanced Intensity Training (BPIT) over 6 weeks. The goal was to see if a structured plan that gradually increases exercise difficulty could improve strength and lower the chance of getting hurt. The study involved 23 heal…

This study tested whether a specific combination of dietary supplements could help healthy adults sleep better and feel less stressed. 115 active participants were randomly assigned to take either the real supplement or a placebo pill for several weeks. Researchers measured chang…

This study tested if adding simple mental tasks to standard walking and cycling exercises could help people with COPD. Over 8 weeks, researchers compared a group doing these combined 'dual-task' exercises with a group doing standard exercises alone. They wanted to see if the adde…

This study tested a cream made with plant extracts and common skin brighteners to see if it safely reduces dark spots left after skin injuries, known as post-inflammatory hyperpigmentation. It involved 25 healthy Malaysian adults who applied the cream for 20 weeks. Researchers me…

This study tested if a new oral medication called NG101 can help manage common stomach side effects, like nausea and vomiting, that people often get from GLP-1 weight-loss drugs like semaglutide. About 120 healthy adults with a body mass index (BMI) between 22 and 35 received a s…

This small study tested whether a pine bark extract supplement could help reduce fatigue and improve recovery after intense exercise. Fourteen healthy adults took either the supplement or a placebo for four days before performing cycling tests. Researchers measured how long parti…

This study compared two different exercise programs for older women to see which one better improves physical fitness and immune system markers. Sixty-six women aged 60-70 did either the 'SI Kumbang' or 'Bugar Lansia' exercise routine three times a week for three months. Research…

This study tested if a short session of static neck stretching could lower blood pressure in healthy adults. Researchers measured blood pressure, tissue stiffness, and heart rate in 25 participants to see if stretching relaxes blood vessels. The goal was to see if this simple act…

This study tested if a newer sedative drug (remimazolam) works better than a standard one (midazolam) for people getting a diagnostic upper endoscopy. Researchers compared the two drugs in 132 healthy volunteers to see which led to a faster procedure and more successful sedation.…

This study tested whether a 4-week group program called 'Dance-Walk' could help adults feel more connected to their bodies, increase their energy, and improve their mental health. Researchers compared 117 people who started the program right away to those who waited, measuring ch…

This study tested whether a new skincare serum is safe for people trying to reduce dark spots left by acne or skin injuries. Thirty-four Malaysian adults with these dark spots used the serum for eight weeks. Researchers checked for any skin reactions and asked participants how sa…

This completed Phase 3 study tested whether AYP-101 injections could safely reduce fat under the chin (double chin) in healthy adults. Researchers enrolled 252 participants with moderate to severe double chin fat and randomly assigned them to receive either the active injection o…

This study tested if a simple writing exercise could help reduce feelings of anxiety and depression. For 14 days, young adults wrote about their deepest thoughts and feelings. Researchers compared whether writing as if talking to yourself or to a loved one worked better.

This study tested whether shining a special low-level laser on the roof of the mouth could help after gum graft surgery. Thirty-six healthy adults who had the surgery were randomly assigned to get the laser treatment right after surgery or just the standard care. Researchers then…

This study tested whether soaking in cold or warm water helps muscles recover faster after a tough workout. Researchers had 30 healthy people do a series of intense jumps to tire their leg muscles. Afterward, participants soaked in cold water, warm water, or did no special recove…

This study tested whether a simple, two-week routine of quiet time in nature could improve a person's sense of spiritual well-being. Researchers asked 41 healthy adults to walk for 10 minutes, sit quietly in nature for 10 minutes while contemplating their connection to it, and th…

This study aimed to understand how taking iron supplements affects the way a new drug called MT-6548 is processed by the body. It involved 61 healthy male volunteers of Japanese descent. Researchers measured the drug's levels in the blood when taken with and without iron to check…

This study tested whether a single dose of the cancer drug selpercatinib (LOXO-292) affects the electrical rhythm of the heart in healthy people. It involved 32 healthy adult volunteers who received the drug, a placebo, and a control medication in a specific order. The main goal …

This early-stage study aimed to check the safety and how the body processes a new compound called BI 3810477. It involved 47 healthy adult volunteers who received either the compound or a placebo. The main goal was to see what side effects might occur and to measure how much of t…

This study tested whether brain scans (MRIs) could be successfully performed on young children without using sedation. Researchers worked with 23 healthy children aged 6 months to 5 years. The goal was to see if this common medical procedure could be done while the children were …

This study aimed to see if a simple, portable EEG headset (which measures brainwaves) can accurately track the same complex brain network activity as an expensive MRI machine. Researchers measured brain activity in 24 healthy adults using both devices while they did attention tas…

This early-stage study tested how an experimental breast cancer drug, imlunestrant, might interact with several common medications. Researchers gave imlunestrant and other drugs to 113 healthy female volunteers to see if they affect each other's levels in the body. The main goal …

This study tested a new tool called the Clock'N'Test, which aims to detect early emotional disorders by measuring how people estimate time. Researchers showed 150 healthy participants short emotional videos and measured if their sense of time changed afterward. The goal was to es…

This early-stage study tested how food and a common heartburn medication (esomeprazole) affect how the body absorbs and processes a new drug called LY4064809. It involved 36 healthy adult volunteers who took the drug under different conditions. Researchers measured drug levels in…

This study tested whether showing people their own blood sugar data after drinking a special milk powder changed how beneficial they thought the drink was. Researchers enrolled 170 healthy Chinese adults aged 45-75. One group could see their glucose monitor readings while drinkin…

This study aimed to create better computer models of human fingertips by taking detailed MRI scans. Researchers scanned the index fingers of eight healthy volunteers while applying different amounts of pressure. The data will help engineers design more realistic robotic hands and…

This study aimed to understand how the body processes a new, slower under-the-skin (subcutaneous) injection of the diuretic furosemide, compared to the standard fast IV injection. It involved 13 healthy volunteers who received both versions of the drug in a specific order. The ma…

This early-stage study aimed to understand how the body processes a new drug called MK-1084 (calderasib). Researchers tested 56 healthy adults to see if taking the drug with food, in a different pill form, or alongside common stomach acid medicine changed how much of the drug got…

This study measured different immune cell levels in the blood of 40 healthy Danish women of reproductive age. Researchers collected blood samples to understand what normal immune system measurements look like in this population. This information will serve as a reference point fo…

This early-stage study aimed to understand how eating food, especially high-fat or low-fat meals, affects how the body absorbs and processes a new drug called HMPL-523. It involved 18 healthy Chinese volunteers who took the drug under different fasting and fed conditions. The mai…

This study aimed to understand how breathing diesel exhaust affects the heart and blood vessels. Six healthy adults aged 50-75, who lack a specific protective gene, breathed three different levels of diesel fumes for two hours each. Researchers measured changes in their blood ves…

This study tested if making the tip of an IV catheter (a small tube placed in a vein) softer and more flexible helps it last longer. Researchers compared two types of catheters in 27 healthy adults to see if the softer material caused less irritation to the vein wall. The goal is…

This was an early safety study to see how healthy people's bodies react to and process a new tablet called D-2570. One hundred healthy volunteers took either the drug or a placebo (a dummy pill) in different doses, and some took it with or without food. Researchers closely monito…

This early-stage study aimed to understand how eating food affects the way the body absorbs an experimental drug called BI 1015550. It involved 12 healthy male volunteers who took the drug both with and without food. The main goal was to measure drug levels in the blood to see if…

This study compared three different exercise programs to see which works best for military trainees. Researchers tested high-intensity functional training against traditional strength training and a combined program over 8 weeks. They measured changes in fitness, body composition…

This early-stage study tested the safety and how the body processes a new tablet made from mulberry twig alkaloids. It involved 62 healthy and overweight volunteers in China. The main goal was to see if the tablets were safe and to measure how much of the drug gets into the blood…

This study tested whether a special audio program teaching about puberty could improve self-image and healthy habits in visually impaired teenage girls. Researchers worked with 46 girls aged 12-18 from two schools. They measured changes in the girls' feelings about themselves and…

This study aimed to understand the precise hand motions and forces used by healthcare workers when inserting an IV catheter. Researchers measured these actions in healthy volunteers using special sensors and cameras. The goal was to use this data to build better training simulato…

This small pilot study aims to develop a new method for measuring how the body breaks down tryptophan, an essential nutrient. Researchers will test this method in 10 healthy young adults by giving them different amounts of tryptophan and tracking its byproducts. The ultimate goal…

This was an early, first-in-human study to check the safety and basic effects of a single dose of a new drug called IBI3032. It involved 40 healthy volunteers and tested how the body processes the drug, including whether taking it with or without food makes a difference. The main…

This early-stage study tested how two experimental liver drugs (denifanstat and resmetirom) interact when taken together. Researchers enrolled 40 healthy adults to measure how the drugs affect each other's levels in the body. The goal was to understand potential interactions befo…

This early-stage study aimed to understand how the body absorbs, processes, and eliminates an experimental cancer drug called BI 1810631 (zongertinib). Researchers gave the drug to 15 healthy male volunteers in two different forms—as a liquid and as a pill—and tracked how much of…

This study tested how a cancer drug (selpercatinib/LOXO-292) affects how the body processes a diabetes medication (repaglinide). It involved 16 healthy adults who took both drugs to measure their levels in the blood and check for safety. The goal was to understand potential drug …

This early-stage study aimed to check the safety and how the body processes a single dose of an experimental medicine called PF-07264660 in healthy Chinese adults. Twelve participants received either the medicine or a placebo (inactive substance) through an IV drip and were monit…

This was the first-ever study in humans of an experimental oral drug called YUQ-A1007. It was tested in 47 healthy volunteers to check its basic safety, how well it's tolerated, and how the body processes it. The drug is designed to act in the gut and early lab research suggests …

This study aimed to understand how specific brain areas help us form and recall personal memories. Researchers used a safe, non-invasive brain stimulation technique on 41 healthy young adults while they performed memory tasks and had MRI scans. The goal was to see if temporarily …

This early-stage study aimed to understand how the body processes and eliminates an investigational antiviral drug called PF-07304814. Five healthy volunteers received a single, low-dose infusion containing a tiny, safe amount of radioactive tracer. Researchers then carefully mea…

This completed study aimed to understand how an athlete's motivation connects to changes in their body's chemistry during intense exercise. Researchers measured hormone and brain chemical levels in 24 national-level male rowers before, immediately after, and one hour after a stre…

This study aimed to understand how the brain and nervous system adapt when people do strength training with a rhythmic beat. Researchers compared different pacing methods during a single workout session in 30 healthy men. They measured brain and muscle signals to see if adding na…

This study aimed to understand how drinking coffee or tea affects the way the body processes an experimental drug called enlicitide. Researchers tested 60 healthy adults, comparing blood levels of the drug when taken with coffee, tea, or just water. The goal was to see if these c…

This small pilot study aimed to better understand how the body digests and uses fiber from wheat bran. Six healthy women ate biscuits containing a special, traceable form of wheat bran. Researchers then collected breath, blood, urine, and stool samples over 24 hours to track how …

This study tested a new brain training method to see if it could improve learning. Researchers gave 65 healthy adults real-time feedback about their brain activity using sounds or vibrations. The goal was to see if people could learn to put their brain in a better state for learn…

This study aimed to understand how two different forms of the drug sotatercept behave in the body. Researchers compared a new liquid version given with an auto-injector pen to an older, freeze-dried version. The study involved 146 healthy female volunteers who could not become pr…

This study tested how the body absorbs and processes an experimental Alzheimer's drug called remternetug when it's given in two different ways. Researchers compared giving the drug with an easy-to-use auto-injector versus a traditional prefilled syringe in 72 healthy volunteers. …

This early-stage study aimed to understand how taking carbamazepine, a common medication, affects how the body processes a single dose of an experimental drug called BI 1810631. It involved 16 healthy male volunteers who took both drugs in a specific sequence. The goal was to gat…

This early-stage study tested the safety of an experimental drug called LY3876602 in 74 healthy volunteers. Researchers gave participants increasing doses to see how their bodies reacted and measured how much drug reached both the bloodstream and spinal fluid. The main goal was t…

This early-stage study tested a new drug called LY3985863 in healthy Chinese volunteers to check its safety and how the body processes it. Twenty-four participants received injections under their skin or a placebo, and researchers monitored for side effects and measured drug leve…

This study aimed to find a new biological marker (biomarker) in the blood to help monitor multiple sclerosis (MS). Researchers compared blood samples from 100 healthy people and people with stable MS who were on different treatments. They measured the levels of a specific seroton…

This study aimed to understand how a drug called palovarotene is processed by the body in people with moderate or severe liver impairment, compared to people with healthy livers. It involved 31 adult participants who were divided into groups based on their liver function. The mai…

This study aimed to see if a new version of a drug pill (Formulation C2) gets into the bloodstream the same way as an older version (Formulation C1). It involved 64 healthy adults who each took a single dose of both pill types at different times. The goal was to confirm the two v…

This study aimed to understand how much of two HIV medications, doravirine and islatravir, pass into breast milk. Researchers measured drug levels in the breast milk and blood of 12 healthy, breastfeeding women over 24 hours after they took a single dose. The goal was to gather s…

This study was a national survey to understand public knowledge and attitudes about epigenetics—the idea that factors like pollution, smoking, or exercise can influence health by affecting how genes work. Researchers surveyed over 2,000 healthy adults from diverse racial and ethn…

This study aimed to understand if spending a lot of time sitting is linked to slower digestion and changes in gut bacteria, which might influence the development of polyps in the colon. Researchers observed 80 adults, measuring their activity levels, digestion speed, and gut bact…

This study aimed to establish normal reference values for the Figure 8 Walk Test, a common clinical assessment of complex walking and turning ability. Researchers measured 1000 healthy adults to create benchmarks that doctors can use to identify mobility problems in patients. The…

This study tested how the body absorbs two different pill versions of an experimental drug called BI 1810631. Researchers also checked if eating food or taking a common heartburn medication changes how the drug works. The study involved 13 healthy male volunteers to gather this b…

This is an early-stage study to check the safety of a new oral drug called THB335 and see how the body absorbs and processes it. It involved 60 healthy adult volunteers. The main goal was to find safe dose levels and understand the drug's basic effects in people.

This early-stage study aimed to understand how a new drug called evobrutinib might change the way the body processes four other common medications: digoxin (for heart conditions), metformin (for diabetes), rosuvastatin (for cholesterol), and sumatriptan (for migraines). The study…

This was the first study to test a new drug called OPT101 in people. It aimed to find a safe dose and see how the body processes it. The study involved 14 healthy volunteers who received either the drug or a placebo. Researchers closely monitored participants for any side effects…

This study investigated whether spraying fruits with melatonin before harvest makes their healthy compounds easier for the body to absorb. Researchers gave 22 healthy adults juice made from melatonin-treated and untreated lemons, oranges, and cherries. They measured compounds in …

This study aimed to find out exactly how much iodine breastfeeding women need daily to stay healthy and support their baby's development. Researchers carefully measured iodine intake and loss in 17 healthy mother-baby pairs over several weeks. The goal was to provide clear eviden…

This early-stage study tested the safety of an experimental inhaled medication called DBM-1152A in healthy Chinese adults. Twenty participants received either the drug or a placebo through a nebulizer once daily for seven days. Researchers monitored for side effects and measured …

This early-stage study aimed to understand how the body absorbs and processes an investigational drug called LY4268989. It tested the drug's safety, how food affects it, and if it interacts with other medications. The study involved 144 healthy adult volunteers, including specifi…

This study aimed to understand if sleep tests give different results when performed at low altitude versus at a person's home at moderate altitude. Researchers compared sleep quality and breathing patterns in 44 healthy adults who live above 1000 meters. Each participant had slee…

This study aimed to understand how a synthetic cannabis-like drug called nabilone affects certain chemicals in the brain of healthy people. Researchers used brain scans (MRI and PET) to measure changes before and after participants took a one-week, low-dose course of nabilone. Th…

This study tested whether applying a massage technique based on the 'tensegrity' concept could change how specific muscles contract and relax. It involved 54 healthy young men aged 19-24. Researchers measured detailed muscle properties before and after the massage to see if the t…

This study aimed to understand how kidney problems affect the way the body processes a cancer drug called LOXO-292 (selpercatinib). Researchers compared a single dose of the drug in 37 people with varying levels of kidney function to healthy volunteers. The goal was to gather dat…

This was an early-stage study to check the safety and see how the body processes a new drug called BI 3006337. It involved 80 healthy male volunteers who received a single injection. The main goal was to find out what side effects might occur and to measure how much of the drug g…

This study aimed to understand how what babies eat influences the development of their gut bacteria and their bones during the first three years of life. Researchers followed 2,760 healthy Chinese infants from birth, collecting information on their diets and measuring their gut m…

This study tested how different designs of custom carbon fiber ankle braces affect the forces and stress on the ankle joint during movement. Nine healthy adults tried three different brace designs while researchers measured their movement, muscle activity, and comfort. The goal w…

This early-stage study aimed to understand how a single dose of the experimental drug KBP-5074 is processed by the body in people with moderate liver impairment compared to healthy people. It involved 12 participants to check for safety and measure drug levels in the blood. The g…

This study tested a new device called Tasso+ that lets people collect their own small blood samples at home or a clinic, supervised by a healthcare provider. Researchers enrolled 200 healthy adults to see if blood collected with this device was as accurate and reliable as blood d…

This early-stage study tested the safety and how the body processes a new drug called RPT1G in healthy adults. Fifty-six participants received either the drug or a placebo in single or multiple doses over several days. The main goal was to check for side effects and understand ho…

This early-stage study tested how the body absorbs two different pill versions of an experimental drug called nerandomilast. It involved 15 healthy adults to see if one version works better than the other and whether taking the pill with food changes how much drug gets into the b…

This early-stage study tested how eating food affects the body's absorption of an experimental cancer drug called BI 1810631 (Zongertinib). Sixteen healthy men took a single dose of the drug once after fasting and once after a meal. The goal was to see if food changes how much of…

This early-stage study aimed to understand how the body absorbs, breaks down, and eliminates an experimental drug called LY4065967. It involved 16 healthy male volunteers who were tracked for about two months. Researchers measured how much of the drug entered the bloodstream and …

This early-stage study aimed to understand how taking multiple doses of a new drug, BI 1015550, affects how the body processes a common sedative called midazolam. It involved 15 healthy male volunteers who took both drugs in a specific sequence. The goal was to gather safety data…

This study aimed to understand how a breast cancer drug, imlunestrant, is processed by the body in people with different levels of liver function. It compared the drug's levels in the blood of women with impaired livers to those with healthy livers. The goal was to gather safety …

This study aimed to understand how a drug called MCI-186 is processed by the body in people with mild or moderate liver problems compared to people with normal liver function. It involved 22 participants who received a single dose of the drug. The goal was to gather safety inform…

This study aimed to improve laboratory methods for studying the tiny energy centers inside blood platelets. Researchers tested different procedures on blood samples from 16 healthy volunteers to find the best way to get accurate measurements. The goal was to ensure future researc…

This early-stage study aims to understand how two investigational drugs (DWC202511 and DWC202512) affect how the body processes another drug (DWP16001). It enrolled 18 healthy adults to measure drug levels in the blood over time. The goal is to gather basic safety and interaction…

This study aimed to understand how many medical students had immunity against Hepatitis B and chickenpox (varicella-zoster virus). Researchers measured immunity levels and vaccination rates in over 400 students. The goal was to gather information to help improve health protection…

This study tested a drug called calderasib in healthy adults. Researchers compared how the body absorbs two different pill versions. They also checked if taking the pill with or without food changes how it works in the body.

This early-stage study aimed to understand how a new drug, BI 655130, is absorbed and processed by the body. It involved 36 healthy volunteers to compare how the drug behaves when given as an injection under the skin versus directly into a vein. The main goal was to check the dru…

This study aimed to see if consuming dairy products like milk or Greek yogurt after exercise has a better effect on bone health and inflammation than a carbohydrate drink or just water. Researchers measured specific markers in the blood of 20 healthy young adults after they compl…

This early-stage study aimed to understand how a new drug called BI 425809 moves through the body and into the brain's spinal fluid. It involved 25 healthy male volunteers who took different oral doses. Researchers measured drug levels in blood and spinal fluid over time to check…

This was an early-stage study to check the safety and how the body processes a new drug called LY3451838. It involved 53 healthy volunteers who received the drug either through an IV or an injection under the skin. The main goal was to see what side effects might occur and to mea…

This early-stage study tested a new drug called LY3522348 in healthy volunteers to check its safety and how the body processes it. Researchers gave different doses to 65 healthy adults and monitored for side effects while taking blood samples to measure drug levels. The goal was …

This early-stage study aimed to understand how an experimental drug called BI 425809 affects how the body processes a common sedative called midazolam. The study involved 15 healthy male volunteers who received both drugs. Researchers measured drug levels in the blood to see if B…

This early-stage study aimed to check the safety and see how the body processes a new oral drug called BI 3009947. It involved 40 healthy male volunteers. Researchers tested different doses and pill formulations to see how much of the drug gets into the bloodstream and if taking …

This study aimed to understand how lipedema affects a woman's physical abilities. Researchers compared 30 women—some with lipedema and some without—by testing their leg strength, walking endurance, pain sensitivity, and swelling. The goal was to gather detailed information to bet…

This study tested how an experimental HIV drug called MK-4646 interacts with a common tuberculosis medication called rifabutin. Researchers gave both drugs to 18 healthy volunteers to measure how rifabutin affects MK-4646 levels in the blood and to check for safety issues. The go…

This study investigated how Parkinson's disease affects the brain's ability to anticipate when something will happen. Researchers compared eye movements and brain activity in 40 people—some with Parkinson's and some healthy—to understand how dopamine influences time expectation. …

This study aimed to understand how different nutrients affect the types and activity of gut bacteria. Researchers tested food ingredients by adding them directly to stool samples in lab dishes, simulating the human colon environment. This allowed them to screen many nutrients wit…

This was an early, first-in-human study to check the safety and basic body processing of a new, unnamed drug called LY3526318. It involved 16 healthy volunteers who took the drug by mouth, either once or multiple times. The main goals were to see how the body absorbs and eliminat…

This study aimed to establish normal ranges for tiny nerve fibers in the skin across different ages and sexes. Researchers collected small skin samples from 300 healthy volunteers to measure nerve fiber density. The results will help doctors better diagnose small fiber neuropathy…

This early-stage study aimed to understand how a single dose of an investigational drug, LY3526318, affects blood flow in the skin of healthy women. Researchers applied a cinnamon-based substance to the skin to measure changes in blood flow and tracked the drug's levels in the bo…

This study tested whether a new, larger autoinjector device delivers the drug mirikizumab into the body in the same way as the currently used, smaller device. It involved 498 healthy volunteers who received injections under the skin. The main goal was to compare how much drug get…

This early-stage study tested how a common antifungal medication (itraconazole) affects blood levels of an experimental cancer drug called BI 1810631. Researchers gave both drugs to 16 healthy male volunteers to measure potential interactions. The goal was to understand safety in…

This study aimed to check if a new version of an experimental drug (BI 1015550) gets into the bloodstream the same way as the original version. It involved 64 healthy adults who each took both versions at different times. The goal was to confirm the two pill formulas are essentia…

This study aimed to understand how a past episode of low blood sugar affects the body's automatic nervous system, which controls things like heart rate and blood pressure. Researchers tested 28 healthy adults to see if a drug called spironolactone could prevent any negative effec…

This study aimed to understand how eating carrots of different colors (red, purple-red, and purple) affects the body's absorption of their natural pigments. Researchers also wanted to see if these pigments might help control blood sugar. Twelve healthy adults drank juices from th…

This early-stage study aimed to understand how the body processes, breaks down, and eliminates an experimental drug called BI 1015550. Six healthy male volunteers took a single, specially labeled dose so researchers could track it. The main goal was to measure how much of the dru…

This study aimed to understand how normal aging affects the heart muscle. Researchers used MRI scans and blood tests to measure heart function and look for signs of tissue scarring (fibrosis) in 74 healthy adults. The goal was to learn how these age-related changes are connected,…

This study aimed to find out which design for the top cuff of a carbon fiber leg brace is most comfortable and works best. Researchers tested four different cuff designs on 35 people, including those with ankle arthritis from past injuries and healthy individuals. They measured h…

This study tested whether lowering heart rate with a medication called ivabradine could improve the flexibility and health of arteries in healthy people. It involved 30 healthy volunteers aged 25-65 who took either the drug or a placebo for 8 days. Researchers measured changes in…

This study aims to understand how the brain adapts when people learn to use their non-dominant hand after a nerve injury to their dominant hand. Researchers will compare brain scans and movement tests from right-handed adults with chronic right-hand nerve injuries to healthy adul…

This study aimed to understand how a drug called MCI-186 is processed by the body in people with severe liver disease compared to healthy people. It involved 12 participants who received a single dose, and researchers closely measured drug levels in their blood. The goal was to g…

This study tested if a new version of the drug zongertinib, made by a different manufacturer, works the same way in the body as the original version. It involved 56 healthy adults who each took both versions. Researchers measured drug levels in the blood to see if they were equiv…

This study aimed to find the best dose of a maqui berry extract (Delphinol®) for improving blood vessel function. Ten healthy young adults took different doses of the extract or a placebo. Researchers measured blood vessel responses to see if the supplement had any effect.

This study tested a new, painless ultrasound method to measure the stiffness and other properties of the tongue in healthy adults. Researchers aimed to create a reliable and standardized measurement protocol. This tool will be used in future studies to understand tongue fat in pe…

This was the first study in humans to test the safety and tolerability of a new drug called MH-001. It involved 58 healthy volunteers who received either the drug or a placebo. The main goal was to see what side effects might occur and to measure how the drug moves through and st…

This early-stage study tested the safety and how the body processes two different versions of an experimental drug called solrikitug. Researchers gave the drug to 32 healthy Japanese and non-Japanese volunteers to check for side effects and measure drug levels in the blood. The m…

This study tested whether different manufacturing batches of the same drug, evobrutinib, are absorbed by the body in the same way. It involved 28 healthy volunteers who took the drug on an empty stomach. Researchers measured the drug levels in the blood and checked for side effec…

This study looked at how eating a high-fat meal or taking common heartburn medication affects how the body absorbs and processes an experimental cancer drug called selpercatinib. Researchers gave the drug to 20 healthy volunteers under different conditions to measure drug levels …

This study aimed to understand how a new drug, BI 1584862, is absorbed, processed, and eliminated by the body. Eight healthy men received a single dose of the drug, which was specially tagged to allow tracking. Researchers measured how much of the drug and its breakdown products …

This study aimed to measure how air flows through the lungs of healthy people and those with COPD (chronic obstructive pulmonary disease). Researchers used a special MRI scan with inhaled helium gas to create detailed airflow maps. The data helps validate computer models that pre…

This study tested how a new medicine for obesity and liver disease behaves in people with different levels of kidney function. Researchers gave a single injection to 42 adults, comparing those with healthy kidneys to those with mild, moderate, or severe kidney problems. The goal …

This early-stage study aimed to understand how the experimental drug LY4064809 is absorbed and eliminated by the body. It involved 10 healthy Chinese adults who took the drug orally and were monitored for about 21 days. The main goals were to measure drug levels in the blood and …

This study aimed to understand how a common antifungal drug (itraconazole) affects the levels of an experimental drug (BI 3031185) in the body. It involved 14 healthy male volunteers who took both drugs. The goal was to gather basic safety and interaction data to inform future re…

This study aimed to understand how not eating enough to fuel intense training affects elite athletes' bodies and minds. Researchers measured stress hormones, brain chemicals, mood, and performance in 27 members of the Polish national rowing team before and after a hard workout. T…

This study aimed to measure how much people bend their head and neck while using a smartphone. Researchers observed 30 healthy young adults as they watched a video on a phone, first while sitting and then while standing. The goal was to gather data on typical postures to better u…

This early-stage study aimed to check if a new drug called LY3985297 is safe and how the body handles it. It involved 140 healthy volunteers who received either the drug or a placebo as a single shot or several shots over time. The main goal was to watch for side effects and meas…

This study aimed to see if a new single tablet containing two common medications (etoricoxib for pain/inflammation and betamethasone, a steroid) gets into the bloodstream the same way as taking the two medications separately. It involved 42 healthy volunteers in Mexico who took t…

This early-stage study aims to understand how an experimental heart drug called CKD-508 interacts with two common medications (midazolam and rosuvastatin) in the body. It involved 24 healthy adult male volunteers to measure drug levels and check for safety. The goal is to gather …

This study aimed to understand how specific areas in the front of the brain help control speech and facial movements. Researchers used MRI brain scans on 23 healthy, right-handed volunteers while they performed tasks. The goal was to map the brain's network for voluntary vocal an…

This study aimed to see if taking a daily dietary supplement for 12 weeks could change gene activity and various health markers in healthy people. Researchers enrolled 92 adults to take the supplement twice daily and tracked changes in their blood, weight, and how they felt. The …

This study aimed to understand how natural variations in a specific gene (GLP1R) affect how the pancreas releases insulin, especially when a person hasn't eaten or has high blood sugar. Researchers studied 21 healthy, non-diabetic adults with different versions of this gene. The …

This small, completed study aimed to understand if patterns in how people use their smartphones (like making calls, sending texts, and moving around) are connected to their body's natural 24-hour rhythms. Researchers tracked six healthy men's phone data and collected blood pressu…

This study aimed to improve a portable brain scanning technique (fNIRS) by finding the minimum number of repeated tasks needed to get a clear brain activity signal. Researchers measured brain activity in 29 healthy, right-handed volunteers while they performed a simple hand movem…

This study tested whether a single dose of the drug evobrutinib causes any unwanted changes in heart rhythm, specifically the QT interval on an ECG. It involved 36 healthy adult volunteers who received the drug, a placebo, and a control medication in a random order. The main goal…

This study aimed to understand how children's reasoning abilities relate to their math skills by looking at brain activity. Researchers scanned the brains of 137 healthy children aged 8-14 while they solved reasoning problems, then compared this brain activity to their math test …

This early-stage study aimed to understand how taking one drug (bosentan) might change how the body processes another drug (nerandomilast). It involved 16 healthy male volunteers who took both drugs in a specific sequence. The main goal was to measure the levels of nerandomilast …

This study tested whether a special juice blend with ingredients like cherry, cocoa, and magnesium could improve sleep and recovery in young, healthy football players. Researchers wanted to see if the supplement worked the same for everyone or if its effects varied from person to…

This study aimed to understand how knee pain changes the way people walk. Researchers gave 34 healthy adults two different injections in the knee—one to cause temporary pain and one as a control—and then measured their walking and jumping movements. The goal was to see if walking…

This small, completed pilot study aimed to see if certain drinks could change appetite hormones and feelings of fullness after a meal. It involved 12 healthy adults who tried the beverages. Researchers measured hormone levels and asked participants about their hunger to understan…

This study aimed to understand how taking carbamazepine (an existing medication) affects how the body processes a single dose of a new drug called evobrutinib. It involved 14 healthy participants who stayed in a research unit for observation. The main goal was to measure drug lev…

This early-stage study aimed to understand how a common antifungal drug (itraconazole) affects the way the body processes a new experimental medication (BI 1015550). It involved 16 healthy male volunteers who received the drugs alone and together. The main goal was to measure dru…

This study aimed to understand how different types of exercise affect a brain chemical called BDNF and lactate levels in the blood. Twelve healthy young adults completed three different workouts: high-intensity sprints, moderate running, and low-intensity jogging. Researchers mea…

This study looked at how raising the head of a bed affects lung movement during breathing. Researchers used a painless ultrasound on 31 healthy adults lying flat, at 20 degrees, and at 40 degrees. The goal is to gather information that could help doctors position patients with br…

This study aimed to understand how a drug called MCI-186 is processed by the body in people with mild or moderate kidney problems compared to people with normal kidney function. It involved 30 participants who received a single dose of the drug. The main goal was to gather inform…

This study collected small blood samples from healthy volunteers to create comparison samples for validating a new blood test that detects cancer cells. Researchers needed cancer-free blood to properly test their detection method in future cancer patients. The study involved 43 h…

This study followed 191 healthy children from a previous study to see how their early diet affects them as teenagers. Researchers checked back when the children turned 14 to compare growth, development, and body composition between those who were fed breast milk, milk-based formu…

This study aimed to understand if eating a specific type of fiber called inulin for one week changes how many calories the body burns while at rest. It involved 61 healthy adults, some with normal weight and some with overweight or obesity. Each person tried two different 7-day d…

This small pilot study tested whether a single dose of the BCG vaccine, commonly used against tuberculosis, could change markers in the blood and spinal fluid related to brain health and the immune system in older adults. It enrolled 20 participants, some with normal thinking and…

This small study aimed to understand how breathing air with higher levels of carbon dioxide (CO2) might affect brain function. Healthy volunteers spent time in a chamber with either normal or elevated CO2 while researchers tested their thinking skills and took blood samples. The …

This small, early-stage study tested how the body absorbs the diabetes medication empagliflozin when taken in different ways. Fourteen healthy volunteers took the drug either as a whole tablet or dissolved in water and mixed with food. The goal was to see if these different metho…

This was the first study to test the experimental drug ZE63-0302 in humans. Researchers gave healthy volunteers single and multiple doses of the drug to check if it was safe and to see how the body processes it. The main goal was to understand the drug's safety profile and how it…

This French study aimed to better understand Netherton syndrome, a rare genetic skin condition. Researchers followed 18 people with the disease to learn how it naturally progresses over time and how it affects the immune system. The goal was to identify new biological targets tha…

This study aimed to measure and compare the chemical contents of three different antibacterial dressings after they were worn for 7 days. It involved 45 healthy volunteers who each wore the dressings. The main goal was to understand how much of the key antibacterial ingredient, c…

This early-stage study aimed to understand how the body absorbs, breaks down, and eliminates a single dose of an experimental drug called BI 1291583. Eight healthy male volunteers received a specially labeled version of the drug. Researchers then carefully measured how much of it…

This study tested new, less invasive devices for collecting blood samples at home compared to standard needle draws in a clinic. Fourteen healthy adults received a single dose of a nasal spray migraine medication (zavegepant). Researchers compared blood levels of the drug measure…

This study tested whether taking a specific probiotic supplement for 12 weeks could help healthy athletes digest and use protein from their diet more effectively. Researchers gave 72 participants either the probiotic or a placebo and measured changes in their digestion, body comp…

This study aimed to find out if applying cold therapy helps healthy young people recover from hard exercise and perform better. Researchers tested two things: cooling after exercise to see if it speeds up recovery, and cooling before exercise to see if it boosts muscle strength. …

This study aimed to understand the health and well-being of people who work in the food supply chain, from farms to stores. Researchers compared 20 active workers with 20 desk-based workers, measuring their nutrition, body composition, stress markers, and quality of life. The goa…

This study tested whether a new, modified version of a drug tablet (HMPL-523) is absorbed by the body in the same way as the original version. It involved 54 healthy Chinese volunteers who took both tablet versions in a specific order. The main goal was to see if the two versions…

This study aimed to better understand how the brain works by using a high-density EEG cap to record brain waves. Researchers worked with 122 participants, including people with epilepsy, brain tumors, and healthy volunteers. Participants wore the cap while resting or performing s…

This was an early-stage study to check the safety and see how the body processes a new drug called BI 3006337. It involved 36 healthy Japanese men who received injections of the drug or a placebo over several weeks. The main goal was to understand the drug's side effects and how …

This study aimed to understand if letting people choose their preferred type of brief mindfulness practice leads to better results than being randomly assigned one. Researchers compared three groups of healthy UK adults: one that chose their practice, one that was randomly assign…

This was the first-ever study in humans for a new oral drug called ZE50-0134. Its main goal was to check the drug's safety, how the body processes it, and its effects in 104 healthy adults. Volunteers received different single doses of the drug or a placebo, and researchers monit…

This study aimed to understand if taking a new experimental drug, BI 1015550, with or without food changes how the body absorbs it. It involved 18 healthy volunteers who took a single dose under different conditions. The goal was to gather basic information to help plan how the d…

This early-stage study aimed to see if a new single pill containing two common heart medications (ticagrelor and aspirin) is absorbed by the body similarly to taking the two pills separately. It involved 24 healthy volunteers to measure drug levels in the blood. The goal was to g…

This study aimed to understand how a special low-lactose milk containing a prebiotic fiber called GOS affects digestion compared to regular milk. Researchers recruited 24 healthy Chinese adults and used MRI scans to measure how their stomachs and intestines processed the two diff…

This study aimed to understand how the body absorbs and processes different types of dietary fats. Healthy volunteers ate muffins made with either palm oil or lard, and researchers used a special scanning technique on their blood to see how the fat molecules changed. The goal was…

This study aimed to understand how a new drug candidate called Ulonivirine moves through a healthy person's body. Eight healthy volunteers received a single dose containing a tiny, safe amount of radioactive tracer to help researchers track it. The main goal was to measure how th…

This study aimed to understand the brain differences in people born with amusia, a condition where individuals have difficulty perceiving musical pitch. Researchers compared 230 French-speaking adults, some with amusia and some without, using brain scans and listening tests. The …

This study tested how different airflow settings on two new high-flow nasal oxygen devices affect lung volume and comfort in healthy adults. Twenty-six healthy volunteers tried the devices at various settings while researchers measured their lung volume and asked about comfort. T…

This study aimed to understand how soreness in the calf muscle affects other muscles in the back and legs, and impacts physical performance like balance and strength. Researchers had 14 healthy young adults do a calf exercise to create soreness, then measured their muscle propert…

This study aimed to find the best way to teach nursing students how to care for a child trapped under rubble, focusing on maintaining their fluid and electrolyte balance. It compared a short lecture to a longer, hands-on simulation training. The goal was to see which method impro…

This study aimed to understand how common sleep problems affect the brain's response to pain medication. Researchers tested healthy adults after disrupting their sleep to see if poor sleep changed how well a pain drug worked and whether it increased the risk of misuse. The goal w…

This early-stage study aimed to understand how the body absorbs and processes different versions of an investigational drug called bimagrumab, both by itself and when given with another drug called tirzepatide. It involved 125 healthy volunteers and lasted about 4.5 months. The m…

This was the first-ever study in humans of a new drug called BI 3034701. Its main goal was to check the safety and side effects of different doses in healthy men and in people who are overweight or obese. Researchers also measured how the drug moved through the body after being g…

This small, early-stage study aimed to understand how much of an experimental drug called BI 1015550 gets into the bloodstream when taken as a pill compared to when it's given directly into a vein. It involved 8 healthy male volunteers to gather basic data on how the body process…

This study aimed to understand how a non-invasive brain stimulation technique works. Researchers used advanced brain scans on 37 healthy volunteers while applying a mild electrical current to the scalp. The goal was to map how this stimulation changes brain activity and chemistry…

This study tested whether APF530, an experimental medication, affects heart rhythm in healthy people. Researchers measured heart activity in 56 volunteers to check for any safety concerns. The study compared APF530 against placebo and other drugs to understand its effects on the …

This study aimed to understand how the human brain allows us to use and improve tools, a key ability in human evolution. Researchers used brain scans (fMRI) on 70 healthy volunteers while they performed tasks, including a challenge to build a tall tower from wire. The goal was to…

This early-stage study aimed to understand how a new drug called BI 1015550 moves through the body and how safe it is. It involved 24 healthy Chinese men and women who received a single dose. The main goal was to gather basic safety data and see how the drug is processed, not to …

This early study aimed to understand how a new drug, olomorasib, is processed by people with different levels of liver impairment compared to healthy people. It involved 46 participants who received a single dose, with a focus on measuring drug levels in the blood and checking fo…

This study aimed to better understand how the brain's wiring changes as people get older. Researchers used two types of advanced MRI scans on 10 healthy adults to create detailed maps of brain connections. The goal was to develop new ways to measure these connections, which could…

This Yale University study aimed to understand how the brain recovers after people stop using cannabis. Researchers followed 162 people, including those dependent on cannabis and healthy non-users, tracking brain activity and thinking skills over four weeks of abstinence. They us…

This early-stage study aimed to understand how liver function affects the way the body processes bulevirtide, a medication for hepatitis D. Researchers compared 74 participants—some with healthy livers and some with impaired liver function—to measure drug levels in the blood and …

This study aimed to create a reference chart showing what normal lung function looks like for healthy Polish children and teenagers. Researchers measured the lungs of 2000 healthy kids aged 3 to 18 using a simple breathing test. The resulting charts will help doctors better ident…

This study aimed to understand the basic science of how muscles grow and shrink. Researchers observed 15 healthy young women, having them exercise one leg while keeping the other leg immobilized in a brace for 10 days. They measured muscle size and strength and analyzed how prote…

This study aimed to understand how the immune cells inside the lungs react when exposed to a substance from tuberculosis (TB) bacteria. Researchers enrolled 17 healthy adults, some who had been exposed to TB and some who had not. They placed the TB test substance directly into th…

This study tested a new, more concentrated version of an experimental drug called RPH-104 in 130 healthy volunteers. The main goal was to see how the drug moves through the body, if it's safe, and if it causes an immune reaction when given as a single shot under the skin or into …

This early-stage study aimed to understand how a new breast cancer drug, imlunestrant, might affect how the body processes other medications. It involved 20 healthy women and measured how the drug changed levels of a common sedative in the blood. The main goal was to gather safet…

This study aimed to understand the food habits, dietary practices, and preferences of older adults in Singapore. Researchers interviewed 200 community-dwelling seniors aged 60 and above from various ethnic backgrounds. The study collected information through questionnaires but di…

This study tested how well a wearable heart monitor patch stays on the skin and how comfortable it is to wear for up to 30 days. Fifteen healthy volunteers wore the patch to see how long it provided clear heart readings and to report on skin comfort. The goal was to gather inform…

This was an early-stage study to understand how a new drug called fosmanogepix is processed by the body and to check its safety. It involved 54 healthy Chinese adults who received either the drug or a placebo, given as a single dose or multiple doses, either by mouth or through a…

This study aims to understand how healthy bodies process ornithine phenylacetate, a compound being researched for liver conditions. Researchers will track how this substance breaks down and moves through the body in 20 healthy volunteers aged 40-70. The study involves blood tests…

This early-stage study aimed to see if a new drug candidate, MT-8554, changes how the body processes two common cholesterol-lowering drugs, simvastatin and rosuvastatin. It involved 28 healthy male volunteers to measure drug levels in the blood and check for safety. The goal was …

This study looked at how special energy-saving window films might affect people's comfort, thinking skills, and stress levels. Researchers tested 41 healthy adults by having them spend time in rooms with different window films and measuring their cognitive performance, body tempe…

This study aimed to find out if shining specific colors of LED light on skin helps it heal faster. Researchers tested this on 10 healthy volunteers by creating small, controlled wounds on their forearms with a laser and then applying different LED lights. The goal was to measure …

This study followed 373 healthy young athletes in Poland, aged 8-16, for one year. Researchers measured their fitness, balance, strength, and quality of life to see if these factors could predict who might get injured. The goal is to learn how focusing intensely on one sport affe…

This early-stage study tested how a new drug called SR750 moves through the body and how safe it is in healthy people. Researchers gave the drug to 40 healthy Chinese volunteers and compared them to others who received a placebo. The main goal was to understand the drug's safety …

This study aimed to find brain activity patterns that signal when people are becoming mentally or physically tired. Researchers measured brain waves in 169 healthy adults while they performed tasks designed to induce either mental fatigue or physical exhaustion. The goal was to i…

This study tested whether a special set of physical activity cards that combine movement with brain games could improve thinking skills in middle school students. Over 12 weeks, 36 healthy students aged 11-14 tried either the new activity cards, traditional activity cards, or no …

This study aimed to understand how different types of massage, given in the morning versus evening, affect brain wave patterns in elite taekwondo athletes. Researchers measured brain activity in 12 healthy male athletes after they received different massages or no massage at all.…

This study aimed to understand if smells in a city environment influence how much people eat. Researchers used virtual reality to simulate an outdoor café for 25 healthy young adults, measuring their food intake and feelings in response to different scents. The goal was to gather…

This early-stage study aimed to check the safety and see how the body processes a new experimental drug called ARC-520, which is designed to treat hepatitis B. It involved 40 healthy adult volunteers who received a single dose of the drug through an IV. The main goal was to find …

This early-stage study aimed to compare how two different versions of the same experimental drug, BI 456906, are absorbed into the bloodstream. It involved 16 healthy adults to see if a new formulation works similarly to the original one. The goal was to gather basic data on how …

This study aimed to understand how a single dose of the cancer medication selpercatinib changes the amount of the cholesterol-lowering drug rosuvastatin in a person's bloodstream. It involved 28 healthy adult participants and measured drug levels and safety over about a month. Th…

This was an early, small study to see how a single dose of an experimental compound called MT-8554 affects the body in healthy people. It involved 20 healthy male volunteers and measured how the drug changed their response to a standard cold pain test. The main goals were to unde…

This early-stage study tested the safety and how the body processes ARC-520 in healthy adults. Researchers gave increasing doses to 54 volunteers to check for side effects and measure drug levels in the blood. The goal was to gather basic safety information before testing in pati…

This study looked at whether a 'flipped learning' teaching method could help nursing students who are naturally more active in the evenings (evening chronotypes). Researchers tested if this approach improved students' motivation and academic performance compared to traditional te…

This study aimed to understand how much of an experimental drug gets into the bloodstream and how the body gets rid of it. It involved 16 healthy female volunteers who could not become pregnant. Researchers gave a single dose containing a tiny, safe amount of radioactive material…

This study tested whether a new drug called BI 1015550 affects the heart's electrical rhythm in healthy people. Forty-six healthy volunteers received different single doses of the drug, a placebo, and a comparison drug to see if it caused any concerning changes. The main goal was…

This early-stage study aimed to understand how the body absorbs two different combinations of the drugs vicadrostat and empagliflozin. It also tested whether taking the drugs with food changes how they work in the body. The study involved 32 healthy adult volunteers who each rece…

This study aimed to understand if two hormones, oxytocin and vasopressin, change how the brain works when given as a nasal spray. Researchers gave 120 healthy adults either oxytocin, vasopressin, or a placebo spray and measured their brain waves while they rested and did simple c…

This study aimed to understand how the timing of your last meal affects your metabolism. Researchers at Johns Hopkins University had 41 healthy young adults eat dinner either early or late relative to their personal body clock, and measured their blood sugar and fat burning overn…

This study aimed to understand how two different capsule versions of the experimental drug olomorasib are absorbed by the body and whether taking it with food changes that absorption. It involved 191 healthy Japanese participants and lasted about six weeks. The goal was to gather…

This study aimed to find a safe way to stop a bad reaction to LSD. Researchers gave LSD to 20 healthy volunteers and then tested if three different medications could reduce or shorten its mind-altering effects. The goal was to provide doctors with a tool to help people who have a…

This study aimed to understand if giving a COVID-19 antibody treatment (casirivimab+imdevimab) affects the body's immune response to the Moderna mRNA-1273 vaccine. Researchers enrolled 295 healthy adults to receive the vaccine at different times after the antibody treatment. The …

This study aimed to find the best way to clean skin before surgery to reduce germs. Researchers tested two different antiseptic solutions and two different application methods (blotting vs. not blotting) on 122 healthy volunteers. They measured how well each method reduced bacter…

This study created a reference database of normal brain scans from 41 healthy adults. The goal is to help doctors better analyze brain images from people with epilepsy by comparing them to these healthy patterns. This could improve the accuracy of locating the source of seizures …

This study aimed to understand how dietary components like caffeine affect the brain. Researchers used a special, non-invasive scanner to measure oxygen levels in the brains of 37 healthy young adults while they did memory and thinking tests. The goal was to see if patterns in br…

This study aimed to find out if drinking only when thirsty is a safe and effective hydration strategy for runners in an extreme, multi-day mountain race. Researchers followed 198 participants of the 2015 Ultra Trail du Mont-Blanc, comparing their blood sodium levels, weight chang…

This study looked at whether having a baby by C-section or vaginal delivery changes the nutrient makeup of a mother's breast milk. Researchers analyzed milk from 250 healthy mothers in China to compare levels of sugars, fats, and proteins. The goal was to see if any differences i…

This study aimed to understand how the brain uses sleep to strengthen skills learned through mental practice, like imagining a movement. Researchers measured brain activity in 51 healthy volunteers while they slept, after they practiced finger movement tasks only in their minds. …

This study aimed to understand how the human brain combines visual and auditory information to recognize gender. Researchers used MRI brain scans on 38 healthy volunteers while they performed a gender classification task. The goal was to map which brain areas are involved and see…

This study aimed to understand if having your sleep interrupted makes you more sensitive to pain. Researchers tested 30 healthy adults by waking them up multiple times over three nights. They then measured how much pain the participants felt from injections in their knee and shou…

This early-stage study tested how a single dose of an experimental drug called cenerimod is processed by the body in people with mild or moderate liver impairment, compared to healthy volunteers. The main goal was to understand if liver problems change how the drug moves through …

This was a first-in-human study to check if a new, undisclosed drug called MT-8554 is safe for people and to see how the body absorbs and processes it. The study involved 135 healthy adult volunteers who received the drug. Researchers closely monitored participants for any side e…

This study aimed to understand how carbamazepine, a drug used for conditions like seizures, affects how the body processes a new drug called nerandomilast. It involved 16 healthy male volunteers who took both drugs in a specific order. The goal was to gather safety data for futur…

This study aimed to understand how a new drug called calderasib (MK-1084) might change how the body processes two common medications: rosuvastatin (a cholesterol drug) and metformin (a diabetes drug). It involved 16 healthy participants who took the medications with and without c…

This small, completed study aimed to understand if gently stimulating nerves in the ear can change how the body processes pain. Researchers tested two types of mild electrical stimulation on 12 healthy volunteers to see their immediate effects on pain sensitivity. The goal was to…

This study aimed to compare how three different formulations (recipes) of an investigational drug called BI 456906 are absorbed into the bloodstream. It involved 30 healthy adult volunteers who each received a single dose of each formulation. The main goal was to see if the new f…

This was an early-stage study to check the safety and see how the body processes a new drug called BI 1015550. It involved 42 healthy male volunteers. Researchers gave participants single and then multiple doses to monitor for side effects and measure how long the drug stayed in …

This was a very early, small study to check if a new drug called BI 1015550 is safe for people and to see how the body processes it. It involved 16 healthy Japanese men who took a single dose of the drug or a placebo. The main goal was to watch for any side effects and measure th…

This study aimed to understand how taking multiple doses of the cancer drug selpercatinib (LOXO-292) changes how the body processes a single dose of the sedative midazolam. It involved 16 healthy adult participants and lasted about 6 weeks. The main goal was to measure drug level…

This completed early-stage study tested how two new drugs, JLP-2302 and JP-1366, move through the body and how safe they are. It involved 55 healthy volunteers with no significant medical conditions. The main goal was to measure drug levels in the blood over time and check for an…

This study looked at whether eating two different types of sweet oranges could improve the body's ability to fight inflammation and cell damage. Twenty healthy adults ate either a special 'Rosy Red' orange or a common 'Olinda' orange daily for four weeks. Researchers measured cha…

This study aimed to establish normal breathing resistance values in healthy adults using a simple technique that requires minimal patient cooperation. Researchers measured 122 healthy, non-smoking adults to create reference ranges for this breathing test. The results will help do…

This study aimed to understand how two new drugs, JW0104/C2402 and JW0105, are processed by the body and to check their safety. It involved 60 healthy volunteers who received single doses. The main goal was to measure drug levels in the blood over time, not to treat any disease.

This study aimed to see if taking a specific 20-ingredient multivitamin daily for three months could improve markers of health, wellbeing, and cognitive function in healthy adults. It involved 37 healthy volunteers who were randomly assigned to take either the multivitamin or a p…

This early-stage study tested the safety and how the body processes two different drug combinations in healthy volunteers. Forty participants received either a combination of two drugs (CTL0201 and CTL0202) or a single drug (CT-L02) in a crossover design. Researchers measured dru…

This early-stage study aimed to understand how the body absorbs a new experimental drug, BI 1015550, when given as different pill versions. It involved 24 healthy volunteers to compare the planned commercial pill formula with an earlier test version and to see if taking the pill …

This research study aimed to understand how everyday over-the-counter and prescription medications might influence a person's mood and their preference for taking certain drugs. Healthy adult volunteers took capsules containing substances like caffeine or nicotine (or a placebo) …

This study tested whether a supplement called MIB-626 (NMN), with or without a special intense exercise program, could boost physical and mental performance in already very fit young adults. 124 healthy, regularly exercising participants were randomly assigned to take either the …

This study aimed to understand how two common medications (itraconazole and phenytoin) affect how the body processes a single dose of an experimental drug called MK-1084 (calderasib). It involved 28 healthy adult participants to measure drug levels in the blood and check for safe…

This study aimed to understand how common antibiotics affect the body's natural systems in healthy people. Researchers gave 108 healthy adults either amoxicillin, azithromycin, or no drug, and then measured changes in their gut bacteria, immune system, and metabolism. The goal wa…

This early-stage study aimed to understand how the body absorbs, breaks down, and eliminates the experimental drug KBP-5074. Seven healthy male volunteers received a single dose containing a tiny, safe amount of radioactive tracer to help track the drug. Researchers measured how …

This study aimed to see if eating a high-fat meal changes how the body absorbs a drug called acoramidis. It involved 18 healthy adults who took the drug once with food and once on an empty stomach. Researchers measured drug levels in the blood to compare the two situations.

This study aimed to understand how a cancer drug called belzutifan might change the way the body processes metformin, a common diabetes medication. It involved 14 healthy adult volunteers who took metformin alone and then with belzutifan. Researchers measured the levels of metfor…

This study aims to understand how exercise changes the body at a deep molecular level. Researchers will analyze blood samples from elite cyclists and recreational athletes before, during, and after a cycling test. The goal is to map how proteins, metabolism, and cellular processe…

This study aimed to understand how meditation practice affects the brain, attention, and emotion control. Researchers measured brain activity, stress markers, and task performance in 169 healthy adults. They used brain scans and simple computer tasks to look for connections betwe…

This study aimed to understand if using common asthma inhalers for a month could affect heart and blood vessel health in young, healthy adults. Researchers compared two inhalers (Ventolin and Symbicort) against a placebo dummy inhaler. They measured blood vessel function and hear…

This small, completed study aimed to see if drinking a Keto5 XOGenius beverage daily could improve markers linked to heart and brain health. It involved 6 healthy adults aged 18-50. Researchers measured things like blood pressure, cholesterol, blood vessel function, and cognitive…

This study aimed to understand how the brain works during different types of robot-assisted arm exercises in people who have had a stroke. Researchers used a special, non-invasive brain scanner (fNIRS) to measure activity in 64 participants—some stroke survivors and some healthy …

This early-stage study aimed to understand how the body processes and eliminates an experimental drug called MK-5475. Eight healthy male volunteers received a single intravenous dose containing a tiny radioactive tracer. Researchers then measured how much of the drug was broken d…

This study aims to understand if the electrical properties of healthy breast tissue, measured by a safe, low-power microwave scanner, are related to breast density seen on mammograms. Researchers scanned 50 healthy women who had recent mammograms to compare the two types of image…

This was an early safety study of an experimental drug called NEU-627. Researchers gave the drug to 74 healthy adults to check for side effects and see how the body processes it. The main goal was to determine if the drug is safe enough for further testing in people with specific…

This study tested a new breathing exercise device developed in Turkey. Researchers wanted to see how using this device for 8 weeks affected lung function and breathing muscle strength in healthy adults. They compared the new device to standard breathing trainers to see if it work…

This study aimed to see if a new drug candidate, BI 3000202, changes how the body processes two common medications: rosuvastatin (a cholesterol drug) and digoxin (a heart drug). It involved 14 healthy adults who took the two common drugs together, then took them again along with …

This study tested whether a home exercise program delivered through a phone app could help handball players stick to their workouts and improve their jumping performance. Researchers compared two different 8-week exercise programs for 28 healthy male players. The main goal was to…

This small study tested a new tool called STAR particles on healthy volunteers. Researchers rubbed these tiny, bumpy particles on the skin to create microscopic punctures, aiming to see if this makes the skin more absorbent for future topical medications like creams or gels. The …

This study tested two medical devices to see if they could temporarily improve blood flow in the legs of healthy volunteers. Twenty participants had one device that uses pressure waves and another that uses gentle electrical stimulation applied to their calf muscles. Researchers …

This small study looked at how monosodium glutamate (MSG) might affect how quickly food leaves the stomach and how the body processes protein after a meal. Researchers tested 13 healthy volunteers to see if regularly taking MSG changed these digestive processes. The goal was to u…

This study aimed to understand if people with complex regional pain syndrome (CRPS) have difficulty with mental imagery—the ability to imagine movements without physically doing them. Researchers compared 129 people across three groups: those with CRPS, those with other musculosk…

This study aimed to understand how many police officers in Bern, Switzerland, had been infected with COVID-19 and what factors increased their risk. Researchers followed over 1,000 officers for a full year, testing their blood for antibodies to see who had been exposed to the vir…

This study aimed to understand how well the body absorbs a new capsule form of CBD (cannabidiol), a compound from cannabis. Researchers tested it in 24 healthy adults, comparing it to a standard CBD product and checking if eating a high-fat meal changed absorption. The main goal …

This study aimed to measure the radiation exposure and body distribution of a new imaging tracer called [18F]PBR111. The tracer is designed to light up brain inflammation in scans for diseases like Alzheimer's and multiple sclerosis. Six healthy volunteers received the tracer and…

This study aimed to create a convincing fake anesthetic injection to improve future research on nerve blocks for pain. Researchers tested a diluted solution on 17 healthy volunteers to see if it could mimic the feeling of a real nerve block without providing pain relief. The goal…

This study aimed to understand how early life experiences with parents and friends influence the quality of romantic relationships in young adulthood. Researchers followed up with 259 young adults from a long-running childhood study and their live-in partners. Participants comple…

This study aimed to understand how fasting changes the body's energy use and how those changes affect the brain. Researchers studied 12 healthy people while they fasted, using brain scans and blood tests to measure metabolism. The goal was to learn the basic science behind how fa…

This early-stage study tested whether an experimental cancer drug called zongertinib changes how the body processes other common medications. Researchers gave 32 healthy men zongertinib along with drugs like a blood thinner (dabigatran), a cholesterol pill (rosuvastatin), a diabe…

This study aimed to understand how the drug MDMA (Ecstasy) changes brain activity related to reward, risk, and emotion. Researchers at Stanford University used MRI brain scans and behavioral tests on 22 healthy adults who had used MDMA before. Participants received either a low d…

This study aimed to understand how taking an existing medication for heart and lung conditions (bosentan) might change the way the body processes an experimental drug (BI 425809). It involved 14 healthy male volunteers who took the drugs in a specific sequence. The goal was to me…

This was a first-in-human study to check the safety and see how the experimental drug TML-6 moves through the body. It involved 72 healthy adult and elderly volunteers who received different doses, some with and without food. The main goal was to find out if TML-6 is safe and wel…

This study looked at how two HIV medications, Azvudine and Aluvia, interact when taken together. It involved 15 healthy adults to measure the drug levels in their blood and check for safety. The goal was to gather information for future HIV treatment combinations, not to treat or…

This study aimed to understand why people feel groggy after waking from a nap, a state called 'sleep inertia.' Researchers used brain scans (fMRI) on 55 healthy adults before and after a 40-minute afternoon nap. They measured how different brain regions communicate to see if this…

This early-stage study aimed to understand how the body absorbs an experimental drug called BI 655130 when it is injected under the skin in different ways and locations. It involved 48 healthy adult volunteers to compare injections in the belly button area versus the thigh, and s…

This study aimed to see if tiny genetic pieces (called miRNAs) from broccoli can be absorbed into human blood after eating it. Researchers tested 20 healthy adults to check if these plant materials could be found in their blood and stool, and if they might influence gut bacteria.…

This study followed 600 healthy infants to understand how different feeding methods—breast milk, milk-based formula, or soy-based formula—affect children's physical growth, body composition, and brain development. Researchers tracked participants from 2 months old until they turn…

This study aimed to understand how the drug ketamine affects the brain's reward and emotion circuits. Researchers at Stanford gave small, controlled doses of ketamine or a placebo to 13 healthy volunteers who had tried ketamine before. They used brain scans and questionnaires to …

Researchers at Mayo Clinic tested a new type of wearable headset that aims to help people hear by sending sound signals through electrodes placed on the skin. The study involved 68 healthy volunteers to figure out the best settings for the device and to see how well people could …

This study aimed to understand how caffeine affects brain activity, anxiety, and decision-making in people with panic disorder compared to healthy individuals. Researchers gave participants either caffeine or a placebo pill and used advanced brain scans and tasks to measure react…

This early study aimed to understand how eating food or taking common medications like heartburn or seizure drugs affects how the body processes a new drug called LY3484356. Researchers tested 82 healthy women who could not become pregnant, measuring drug levels in their blood an…

This study tested how reliable a non-invasive, chest-strap-like device is for measuring the heart's pumping power (stroke volume) in healthy people. Twelve volunteers had their heart function measured at rest and while cycling on a stationary bike, repeating the tests on differen…

This early-stage study aimed to understand how a new cancer drug called zongertinib might affect the way the body processes three other common medications: a sedative, a heartburn drug, and a diabetes medication. It involved 16 healthy male volunteers who took the other drugs alo…

This study aimed to understand if the order you eat foods in a meal—specifically, eating carbohydrates last versus first—affects blood sugar levels in elite female athletes during their normal training. Twenty-two healthy athletes wore a continuous glucose monitor for six days at…

This study aimed to understand if a person's recent eating state—being hungry or full—affects how they answer common questionnaires about their general appetite and eating behaviors. Researchers enrolled 33 healthy adults to complete these surveys both before and after eating a s…

This study aims to understand 'rebound pain,' a severe pain spike some people feel when a numbing nerve block from surgery wears off. Researchers tested 40 healthy volunteers by giving them a numbing injection in the arm and then measuring their pain sensitivity as it wore off. T…

This study tested a new exercise approach for healthy people. Researchers wanted to see if adding arm cycling to leg cycling lets people exercise longer than using legs alone. The goal is to gather information that might later help people with lung disease who find regular exerci…

This study aimed to understand how taking four dietary supplements daily for 12 weeks, along with making lifestyle changes, affects the body. Researchers measured changes in gene activity, blood markers, sleep, gut health, and overall wellness in 97 healthy adults. The goal was t…

This study aimed to understand how THC, the main active compound in cannabis, changes how immune cells work at a genetic level. Researchers gave THC to 56 people, some with HIV and some without, to measure changes in their genes and immune proteins. The goal was to gather basic k…

This study tested a new robotic system designed to hold a person's head perfectly still. Researchers used motion-tracking cameras to measure how much healthy volunteers' heads naturally moved while lying down. The data collected will help engineers build a better device to keep b…

This study aimed to understand how two common medications, itraconazole and rifampin, affect how the body absorbs and removes the cancer drug selpercatinib. It involved 24 healthy adult participants who took selpercatinib alone and then with the other drugs. The goal was to gathe…

This early-stage study tested the safety of an experimental drug called KBP-5074 in healthy volunteers and people with mild to moderate kidney problems. Researchers gave increasing doses to 26 participants to see how their bodies handled the drug and to check for side effects. Th…

This study aimed to understand how well our bodies absorb healthy plant nutrients from blueberries. Researchers compared two types of blueberries to a protein bar with matching nutrients and a control meal. They measured these nutrients in the blood and urine of 29 healthy volunt…

This study aimed to understand if certain food components that affect gut bacteria can change how the body automatically controls heart rate and breathing. Fourteen healthy young adults tried different starch supplements and a placebo over several weeks. Researchers measured chem…

This study aimed to see if a new 3D-printed bicycle saddle improves blood flow to the penis compared to two popular models. Researchers measured oxygen and carbon dioxide levels on the skin of the penis in 14 elite male cyclists while they rode stationary bikes. The goal was to g…

This study tested how accurately a new finger-tip oxygen monitor works. Researchers temporarily lowered oxygen levels in 12 healthy adults and compared the monitor's readings to blood tests. The goal was to see if this device, designed for sleep monitoring, provides reliable meas…

This early-stage study aimed to understand how a new drug, BI 1015550, is absorbed and processed by the body. It involved 12 healthy Japanese male volunteers who received a single oral dose. The main goal was to measure the drug's levels in the blood over time to see how the body…

This study aimed to understand how the body digests and uses protein from milk, comparing whole protein to protein that has been pre-broken down. It involved 26 healthy adults to measure how protein moves through the gut and is absorbed. The goal was to gather basic knowledge abo…

This study aimed to see if a new test inhaler delivers the medicine tiotropium into the bloodstream in a similar way to an already approved inhaler (Spiriva Respimat). It involved 40 healthy adult volunteers who tried both inhalers in a specific order. Researchers measured the dr…

This early-stage study tested how an experimental drug, KBP-5074, interacts with two other common medications. It involved 24 healthy adults to see if these other drugs change how much KBP-5074 stays in the body. The goal was to gather basic safety information to guide future res…

This study tested whether a supplement made from Cornelian cherries could improve heart, blood vessel, and breathing function in healthy amateur runners. Eighteen runners over age 45 took the cherry supplement or a placebo for four weeks each. Researchers measured their blood pre…

This study aimed to find better, more objective ways to measure chronic muscle pain (myofascial pain). Researchers used advanced imaging and sensing techniques on 96 adults, some with neck/shoulder pain and some without, to look for physical signs in the muscles and tissues. The …

This study aimed to check how accurately a special research treadmill can deliver controlled pushes or disturbances to a person's balance. Researchers at Mayo Clinic tested the treadmill on 12 healthy adults to see if the machine's movements matched what was commanded. The goal w…

This study explored whether performing mental tasks while receiving non-invasive brain stimulation could make the stimulation more effective at changing brain activity. Researchers worked with 51 healthy adults who completed simple thinking tasks while receiving brief magnetic pu…

This study aimed to see if taking a new drug candidate (BI 1015550) changes how the body processes two existing medications for lung scarring (nintedanib and pirfenidone). It involved 14 healthy male volunteers. Researchers measured drug levels in the blood to check for safe inte…

This was the first study in humans for a new drug called PROT-001. Its main goal was to check if the drug is safe and to see how the body absorbs and processes it. The study involved 102 healthy adult volunteers and tested single doses, multiple doses, and how food or age might a…

This study aimed to understand how kidney problems affect how the body processes an experimental medicine called BI 1015550. It involved 26 adults, some with healthy kidneys and some with moderate or severe kidney impairment. Each participant took a single dose, and researchers m…

This early-stage study aimed to understand how the body absorbs and processes Azvudine tablets in healthy adults and elderly volunteers. Researchers gave small doses to 24 participants and closely monitored drug levels in their blood and checked for any side effects. The goal was…

This was the first study in humans to test a new drug called KBP-5074. Researchers gave single, increasing doses to 46 healthy volunteers to check for side effects and see how the body absorbs and processes the drug. The goal was to gather basic safety information to help plan fu…

This study aimed to see if a newer training method called blood flow restriction (BFR) is better than standard strength training for building leg muscle. Researchers measured the strength of 16 healthy adults over 16 weeks, comparing the two methods. The goal was to gather data t…

This study aimed to see if taking a new drug called evobrutinib changes how the body processes a common birth control pill. Twenty healthy female participants took both the new drug and the birth control pill for a short period while living at a research clinic. Researchers measu…

This study aimed to understand how a new drug, PF-07054894, is absorbed, processed, and eliminated by the body. It involved 10 healthy adult male volunteers who received the drug orally and sometimes by injection, with a tiny radioactive tag to help track it. The main goal was to…

This was a first-in-human study to check the safety and see how the body processes a new drug called BI 706321. It involved 73 healthy male volunteers who received either the drug or a placebo. The main goals were to see if the drug was safe at different doses and to measure how …

This study aimed to understand if a common immune signal (IL-6) changes how a hormone (glucagon) controls levels of amino acids, which are the building blocks of protein, in the blood. Researchers tested 26 healthy volunteers by giving them either a saline solution or a drug that…

This study aimed to understand how a drug called calderasib (MK-1084) behaves in people with moderate to severe kidney problems compared to healthy people. Researchers gave a single dose to 34 participants and measured drug levels in their blood and urine over time. The goal was …

This early-stage study aims to understand how the body processes different versions of an experimental drug called DA-5222. Researchers will compare taking one combined pill versus taking three separate pills that make up the same drug. The study involves 40 healthy adults who wi…

This study aimed to understand how a drug called cenerimod is processed by the body in people with severe kidney impairment. It compared 16 participants—some with healthy kidneys and some with severe kidney problems—after they took a single dose. The main goal was to check safety…

This study aimed to understand how specific protein components, called branched-chain amino acids (BCAAs), affect muscle growth and the body's ability to manage blood sugar. Researchers compared two drink formulas in 24 healthy young volunteers to measure their muscle's response.…

This early-stage study tested how a common antibiotic (erythromycin) affects the levels of an experimental drug (BI 1291583) in the body. It involved 20 healthy adults to see if taking both drugs together changes how the experimental drug is processed. The goal was to gather basi…

This study aimed to understand if drugs that affect brain chemicals like serotonin (found in psychedelics like MDMA and psilocybin) can cause lasting positive changes in how people behave socially. Researchers gave different substances to 122 healthy adults and measured things li…

This study aimed to understand the nature of memory complaints in people with cancer, specifically brain tumors or breast cancer. Researchers compared 426 participants, including patients and healthy controls, to see if they reported more issues with remembering future plans (pro…

This early-stage study tested the safety and how the body processes lebrikizumab in healthy Chinese volunteers. Twenty-four participants received a single injection of either the drug or a placebo. Researchers monitored side effects and measured how quickly the drug entered and l…

This study aimed to understand how the brain controls movement by comparing eye movements in different patient groups. Researchers tracked eye movements in 14 participants with dystonia, essential tremor, Parkinson's disease, and healthy volunteers. The goal was to see if differe…

This early-stage study aimed to understand how the body processes an experimental drug called BI 706321 when taken with a common antifungal medication, itraconazole. It involved 14 healthy male volunteers who took the drugs in a specific sequence. The goal was to measure drug lev…