One vaccine dose enough for COVID survivors? new study investigates

NCT ID NCT04824638

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether people who had COVID-19 more than 5 months ago need only one dose of the Pfizer mRNA vaccine, instead of the usual two. It included 267 healthy adults aged 18-45 or 65 and older, some with prior infection and some without. Researchers measured antibody levels to see if a single dose provides strong and lasting protection.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Infections infectious disease COVID-19 prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CIC 1405 , CHU Clermont-Ferrand

    Clermont-Ferrand, 63000, France

  • CIC 1427, Hopital Saint-Louis

    Paris, 75010, France

  • CIC1412, CHRU Brest

    Brest, 29609, France

  • CIC1413 , Hôtel Dieu - CHU Nantes

    Nantes, 44093, France

  • CIC1415, CHRU Tours Hôpital Bretonneau

    Tours, 37044, France

  • CIC1417, hôpital Cochin

    Paris, 75 679, France

  • CIC1430, Hôpital Henri Mondor

    Créteil, 94000, France

  • CIC1434, Nouvel Hôpital Civil - Hôpitaux Universitaires de Strasbourg

    Strasbourg, 67091, France

  • Centre de Recherche Clinique, CHU Côte de Nacre

    Caen, 14000, France

  • Service des maladies infectieuses, CHU de Caremeau

    Nîmes, 30029, France

  • URCI, Hôpital Lyon Sud

    Pierre-Bénite, 69310, France