Tiny needle particles could make skin creams work better

NCT ID NCT06004973

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested how to best apply STAR particles—tiny particles covered with microneedles—to healthy skin. The goal was to find the right pressure and rubbing method to create small punctures that could help future topical medications work better. Twenty healthy adults took part, and researchers measured skin water loss and pain to determine the best application method.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

STAR particles (microneedle-covered particles in aloe vera gel)

What this could lead to

If successful, this could help develop better ways to deliver topical medications through the skin.

What could go wrong

This is a very early, small pilot study in healthy volunteers with no active drug. Results may not apply to people with skin conditions or to actual drug delivery.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Emory Children's Center

    Atlanta, Georgia, 30322, United States