Healthy volunteers help test safety of experimental drug NEU-627
NCT ID NCT06900751
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study tested a new drug called NEU-627 in 74 healthy adults to see if it is safe and how the body processes it. Participants received either the drug or a placebo, and researchers monitored side effects and drug levels in the blood. The goal was to gather basic safety information before testing the drug in people with a disease.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
-
74 people
The number who actually took part.
- Started
-
Jun 2025
- Finished
-
Oct 2025
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 60 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: Participants are eligible to be included in the study only if all of the following criteria apply. 1. Male and female participants must be 18-60 years, inclusive, at the time of signing the informed consent; 2. Participants must be in good general health according to the judgment of the Investigator per local guidance; 3. Participants who have a body mass index (BMI) of 18-32 kg/m2 (inclusive); 4. When engaging in sex with a woman of child-bearing potential, both the male participant and his female partner must use highly effective contraception; 5. Legally and ethically capable of giving signed informed consent which includes compliance with the requirements and restrictions listed in the informed consent form (ICF) and in this protocol. Exclusion Criteria: Participants are excluded from the study if any of the following criteria apply. 1. Clinically significant infection and/or dermatological, cardiovascular, hematological, renal, hepatic, pulmonary, endocrine, gastrointestinal, immunological, neurological, or psychiatric disease which could interfere with, or the treatment for which might interfere with, the conduct of the study or which would, in the opinion of the Investigator, unacceptably increase the participant's risk if he/she were to participate in the study; 2. Any history of malignant disease in the last 5 years; 3. Presence of clinically relevant immunosuppression from, but not limited to, immunodeficiency conditions; 4. Use of or plans to use systemic immunosuppressive or immunomodulating medications during the study or within 3 months prior to the first study drug administration; 5. Current infection that requires systemically absorbed antibiotic, antifungal, antiparasitic or antiviral medications; 6. Positive screen for hepatitis B surface antigen, hepatitis C antibody, or human immunodeficiency virus antibody/antigen; 7. History of active, latent, or inadequately treated tuberculosis infection. Additional details and criteria are outlined in the full study protocol.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
New Zealand Clinical Research
Grafton, Aukland, 1010, New Zealand
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