HEALTHY

This early-stage study is testing two new vaccine candidates (V350A and V350B) designed to prevent diseases caused by Epstein-Barr virus (EBV), which is linked to mononucleosis, multiple sclerosis, and certain cancers. The trial will enroll 200 healthy adults to primarily assess …

This study is testing an experimental vaccine, called V181, to see if it can safely prevent dengue fever in healthy children and teenagers. It will involve about 12,000 participants aged 2 to 17 years old. Researchers will compare the vaccine to a placebo (a shot with no active m…

This early-stage study is testing the safety and immune response of a new vaccine called V118E, designed to protect against illnesses caused by pneumonia bacteria. Researchers will enroll 126 healthy adults to monitor for side effects like injection-site reactions, fever, or fati…

This large study is testing whether a new vaccine given to healthy pregnant women can safely protect their newborns from Group B Strep (GBS), a serious bacterial infection. About 6,000 participants will receive either the vaccine or a placebo (saltwater) shot during pregnancy. Re…

This study is testing a new COVID-19 booster vaccine given as a nasal spray. Researchers want to see if it is safe and how well it triggers an immune response in the nose and body compared to the standard mRNA booster shot. The trial will enroll 238 healthy adults in France who h…

This early-stage study aims to understand how the body absorbs a new weight management medicine when it's injected into different areas, like the thigh, arm, or abdomen. It will involve 54 adults who are overweight or have obesity, who will receive a single dose. Researchers will…

This is an early-stage study to check the safety and side effects of a new drug called LY4057996 in healthy volunteers and people with Type 1 or Type 2 diabetes. Researchers will give the drug as an injection under the skin or into a vein and measure how the body processes it. Th…

This is the first study in humans to test the safety and side effects of a new drug called LY4298445. It will involve both healthy volunteers and people with systemic lupus erythematosus or rheumatoid arthritis. The main goal is to see how the body handles the drug and to find a …

This is an early-stage study to check the safety and how the body processes a new oral drug called BGM0504. It will involve 75 healthy, overweight, or obese Chinese adults who do not have diabetes. Researchers will give participants either the drug or a placebo (inactive pill) an…

This study is testing a new inhaled nasal medication called Optate for people with early COVID-19 symptoms. Researchers want to see if this treatment can reduce the amount of virus in the nose and lungs and help people feel better faster. The study involves 40 participants who ha…

This early-stage study is testing whether transferring healthy gut bacteria from a donor (a fecal microbiota transplant) can improve both gastrointestinal problems and core autism symptoms. It will involve 60 participants aged 7-30 with autism and gut issues. Researchers aim to s…

This study is testing a new portable breathing device designed for use in emergencies before a patient reaches the hospital. It aims to see if people without medical training can easily use the device to help someone experiencing sudden, severe breathing failure. The research wil…

This early-stage study is testing a new drug called LY4213663 to see if it's safe and how the body handles it. The research involves both healthy volunteers and people with rheumatoid arthritis to check for side effects and measure drug levels in the blood. This is the first step…

This is an early-stage study to check the safety and how the body processes a new drug called LY4086940. It will involve about 201 healthy people and people who are overweight, have obesity, or have type 2 diabetes. The main goal is to see if the drug is safe and well-tolerated a…

This study is testing whether adding a digestive enzyme called lactase to milk helps premature babies gain weight better. It will involve 100 premature infants, born between 28 and 34 weeks, who are receiving most of their nutrition from milk. The goal is to see if the enzyme hel…

This study aims to see if two different versions of the drug survodutide work the same way in the body. It will involve 80 adults who are living with overweight or obesity. Participants will receive both drug versions in a random order to compare how much of the drug gets into th…

This early-stage study is testing a new weight loss pill called MK-4082. Researchers want to see if it is safe and how the body processes it in healthy adults who are overweight or have obesity. The goal is to find a safe dose for future studies, as this pill could offer an alter…

This early-stage study aims to check the safety and how the body processes a new drug called LY3549492 in healthy adults who are overweight or have obesity. About 120 participants will receive multiple doses over approximately 8 weeks while researchers monitor for side effects an…

This is an early-stage study to check the safety and basic effects of a new investigational drug, LY3938577, for Type 1 Diabetes. It will involve healthy volunteers and people with well-controlled Type 1 Diabetes. Researchers will measure how the drug moves through the body and c…

This study is testing a special training program that combines physical exercises with brain games. It aims to help people with thinking and movement problems after a stroke or from a rare condition called Moyamoya disease. Researchers will compare this combined training to stand…

This is an early-stage study to check the safety and side effects of a new drug called LY4064912, which is being developed for weight management. It will involve 144 healthy and overweight participants who will receive the drug as an injection under the skin or through an IV. Res…

This study is testing whether using a special system that supports movement and different positions during labor leads to better birth outcomes for first-time mothers. It compares standard hospital care to care that includes this mobility system, with the main goal of seeing if i…

This early-stage study is testing the safety and side effects of a new Alzheimer's drug called LY4006895. Researchers will give the drug to healthy volunteers and people with early memory problems from Alzheimer's disease to see how their bodies handle it. The study will measure …

This study aims to develop and test a new diagnostic tool using RNA sequencing (RNA-Seq) to find the genetic causes of rare diseases. It will enroll about 105 participants, including healthy people, patients with known diagnoses, and patients who remain undiagnosed after standard…

This study is testing how well two wearable devices (a finger sensor and a wrist sensor) can detect irregular heartbeats in healthy people. Researchers will compare the devices' readings against a standard medical-grade heart monitor. The goal is to see if these wearable devices …

This is the first study in people to test a new imaging agent called NeuCaVis. The goal is to see if it is safe and how it moves through the body of healthy volunteers. Researchers hope this new agent will one day help doctors see inflammation in the brain and heart more clearly …

This study is testing a new smart shirt called AuReha to see if it can accurately measure arm and shoulder movements. Researchers will compare its measurements to those taken with a standard flexible ruler (goniometer) and video analysis. The goal is to validate the shirt for fut…

This study is testing a new blood marker to detect active inflammation in the heart caused by sarcoidosis. It aims to provide a simpler and safer alternative to current complex scans. The research will involve 120 participants, including people with sarcoidosis, heart attack pati…

This study is testing a new 3D imaging system that gives eye surgeons a live, detailed view inside the eye during surgery. The goal is to see if this technology helps surgeons perform delicate procedures more precisely and safely. The study is enrolling patients undergoing variou…

This study is testing a new, automated MRI scanning method designed to measure liver fat and iron much faster than current techniques. Researchers aim to create a reliable, 'single-button' scan that takes less than five minutes in the machine. They are recruiting 200 participants…

This is a very early safety study to test a potential new diagnostic tool called HB-2121 for celiac disease. Researchers will give a single dose to 18 adults (some with celiac disease, some healthy) and monitor them for 30 days to check for side effects and see how the body proce…

This study is testing a new, cuffless wrist-worn device that measures blood pressure from your radial artery. Researchers will compare its readings to those from a standard arm-cuff monitor in 91 healthy volunteers, some with normal and some with high blood pressure. The goal is …

This study is testing how well a new wearable sensor from Owlet measures heart rate and blood oxygen levels in toddlers and preschoolers. Researchers will compare the device's readings to those from an FDA-approved medical monitor in 90 healthy children aged 19-60 months. The goa…

This study is testing a new device that scans fingernails to check for signs of type 2 diabetes. Researchers will compare the scan results to standard blood sugar tests in 100 adults, some with and some without known diabetes. The goal is to see if this non-invasive scan can accu…

This study is testing a new, low-cost tool to take pictures inside the lower intestines. The tool is a tiny capsule, about the size of a vitamin pill, attached to a thin string. Doctors will gently guide the capsule up the colon in awake participants to see if it can capture clea…

This study is testing a new, portable ultrasound device called POROUS that measures bone density without using X-rays. Researchers want to see if it works as well as the current standard DXA scan, which is a large, stationary X-ray machine. They are enrolling 350 healthy men and …

This study is testing whether a 9-week group cycling program is better than a single training session at helping adults who don't cycle regularly to start cycling more often. Researchers will compare the two approaches to see which one leads more people to cycle weekly after a ye…

This study is creating and testing a Spanish-language version of a home safety program for Latinx families. Researchers are working with community centers to adapt videos and materials to be culturally relevant for caregivers of children ages 2-5. The goal is to see if the tailor…

This study is testing a special neck-training device to see if it can help prevent concussions in young hockey players. Researchers will measure if using the device improves neck strength and brain function in 60 healthy players. The goal is to see if a stronger neck can better p…

This study aims to find out if teaching people to eat more potassium-rich foods is easier and more effective for improving blood vessel health than teaching them to cut back on salt. Researchers will enroll 32 generally healthy young adults who typically eat a lot of salt. Partic…

This study is testing whether a mobile app for parents can help their 3-4 year old children follow healthy daily movement guidelines. Researchers will compare 80 families using the app to a group that gets it later. The app provides weekly tips and goals to encourage more physica…

This study aims to find the best way to give two important vaccines during pregnancy: one for RSV (a common respiratory virus) and one for whooping cough (Tdap). Researchers want to see if giving both shots at the same doctor's visit or at separate visits is more practical, safe,…

This study is testing whether a daily fisetin supplement can help support healthy aging in middle-aged and older adults. Fisetin is a natural compound found in fruits like strawberries, and animal studies suggest it might reduce inflammation linked to aging. For 7 weeks, 120 heal…

This study is testing whether adding technology support to basic health education helps older adults who live alone and feel their memory is slipping to become more physically active. All 86 participants will get a fitness tracker and weekly goal reminders, but half will also get…

This study is testing whether taking a beetroot-based supplement at night can help people sleep better and improve heart and blood vessel health. Researchers will measure changes in sleep quality, daytime sleepiness, and blood pressure in healthy adults. The goal is to see if thi…

This study is testing whether eating grape powder every day for a month can help improve muscle strength and thinking skills in healthy women over 65. Researchers will enroll 35 participants to take grape powder, equivalent to three servings of fresh grapes daily, and measure cha…

This study is testing whether a special vacuum-sealed wound dressing helps reduce complications and improve healing after breast reduction surgery. Researchers will compare this special dressing against standard adhesive dressings in women undergoing the procedure. The study will…

This study is testing a new rehabilitation program to help people recover walking ability after a recent spinal cord injury. Researchers will first test participants' blood and spinal fluid to find the best time to start a 12-week program of walking downhill on a treadmill while …

This study is testing a special group exercise program to see if it helps healthy older adults think more clearly, move better, and feel better overall. Researchers will compare it to a different group activity focused on brain training. About 158 participants will attend group s…

This study is testing whether special breathing muscle training can help amateur CrossFit athletes. About 94 healthy adults who do CrossFit will either use a breathing trainer device or a fake device during their regular workouts for 12 weeks. Researchers want to see if the breat…

This study is testing whether giving children a small prize or incentive helps reduce their fear and anxiety when they need to undergo a medical procedure. Researchers will work with about 187 children, aged 6 to 17, who are getting a procedure and are supported by a child life s…

This is a first-in-human study to check the safety of a new drug called FZ008-145 and see how the body processes it. Researchers will also test if it affects how long healthy volunteers can tolerate cold-induced pain. The study involves about 190 healthy adults and will test diff…

This study is testing whether a new virtual reality (VR) system is easy and comfortable for stroke survivors to use for arm and hand rehabilitation. The system uses a camera to track hand movements and shows patients a virtual 'mirror' of their healthy hand moving, which may help…

This study is testing how easy it is for healthy adults to take a new probiotic supplement and whether it helps with common issues like bloating, irregular bowel movements, and low energy. Over 30 days, 40 participants will take the supplement and report on their gut symptoms, fa…

This study is testing whether eating grape powder before a stressful mental task can help protect brain blood flow, thinking skills, and mood in healthy young adults. Participants will try both a high-flavonoid grape powder and a control powder to see which works better. The rese…

This study is testing whether a science-based mobile app called 'Flourish' can improve the mental and emotional well-being of college students. Researchers will enroll 2500 students to compare using the app alone, using it with a friend, or continuing with usual campus resources …

This study is testing whether a krill oil supplement called Lysoveta can help improve memory and thinking skills in healthy adults aged 50-75 who have noticed their own memory slipping. About 138 participants will be randomly assigned to take either the supplement or a placebo (a…

This study aims to see if taking a dietary supplement called citicoline for four weeks can improve mood in healthy adults. Researchers will compare the effects on mood, sleep quality, and stress levels in 90 volunteers against a placebo pill. The goal is to understand if this sup…

This study is testing if taking sodium bicarbonate, a common supplement, can help well-trained cyclists perform better during long, intense rides. Participants will complete two lab-based cycling sessions—one with the supplement and one with a placebo—to see if it improves their …

This study is looking at whether drinking milk or eating yogurt can help improve children's memory, attention, and thinking skills over a few hours. Researchers will test healthy kids aged 9-14 after they have different types of dairy (full-fat, low-fat, or fat-free) or skip a sn…

This is an early-stage study to check the safety of a new drug called M5542 when given as an injection to healthy people. Researchers will give different doses to small groups of participants and closely monitor for any side effects. The main goal is to see how the body handles t…

This study aims to understand how a single 30-minute exercise session affects hunger and hormone levels in men who are severely restricting their calories. Researchers will compare three groups: one eating normally, one on a very low-calorie diet, and one on the same diet but wit…

This study aims to understand how social behaviors and brain connections develop differently in infants who have a higher chance of developing autism. Researchers will follow 100 infants, some with an older sibling with autism and some without, from 3 months to 3 years old. They …

This study aims to test if special sensors can reliably measure the forces inside carbon fiber ankle-foot braces (AFOs). Researchers will recruit 60 participants, including healthy adults and people who regularly use AFOs with or without nerve damage. The goal is to gather data t…

This is a small pilot study to test if a new research method works. Researchers want to see if cooling the thigh muscles changes how those muscles activate during strong contractions. They will recruit 24 healthy young adults to perform leg exercises under normal and cooled condi…

This is an early safety study testing a new medicine called PF-07985631, which is being developed to treat a kidney disease called IgA nephropathy. The study involves 92 healthy adult volunteers who will receive either the study medicine or a placebo (inactive substance) via inje…

This study aims to understand how taking a sugar molecule called sialic acid changes the community of bacteria in the gut, especially focusing on potentially harmful types. Researchers will give sialic acid to 42 healthy volunteers and analyze their stool samples before and after…

This study is testing if a gentle electrical stimulation behind the ear can affect insulin and blood sugar levels in healthy people. Researchers are studying 30 volunteers to see if stimulating a specific nerve (the vagus nerve) through the skin changes these levels. The goal is …

This study aims to understand what happens in the brain of people with Visual Snow Syndrome (VSS), a condition where people constantly see tiny flickering dots. Researchers will compare brain scans and vision tests from 100 people, including those with VSS, those with migraines, …

This research aims to understand how people who know two languages control and switch between them during different tasks like listening, speaking, and naming pictures. The study will involve 360 healthy adults who are proficient in either Mandarin and English or American Sign La…

This study aims to understand if healthy older African American adults experience a greater reduction in kidney blood flow during exercise and stress compared to White adults. Researchers will measure blood flow in 12 healthy older participants using non-invasive ultrasound while…

This small pilot study aims to understand if men and women wake up differently from a common anesthesia drug called dexmedetomidine. Researchers will enroll 12 healthy volunteers to measure how long it takes them to become responsive after the drug is stopped. They will also test…

This study is testing whether two different ways of giving the drug survodutide—using a pre-filled syringe versus a pre-filled pen—work the same way in the body. It involves 56 healthy adults or adults with overweight or obesity. Researchers will take regular blood samples to mea…

This study aims to understand how nerves in the gut behave differently in people with Irritable Bowel Syndrome (IBS) compared to healthy people. Researchers will take small tissue samples from the rectum of both IBS patients and healthy volunteers. They will then study the nerve …

This study aims to understand how everyday skin treatments like antifungal creams and mild steroid ointments change the mix of bacteria and other microbes living on healthy skin. Researchers will apply these creams to small areas on the arms of 24 healthy adult volunteers and the…

This Mayo Clinic study aims to understand how common undiagnosed sleep problems are in healthy Somali American adults. Researchers will measure participants' sleep and blood pressure over 24 hours to see if poor sleep is linked to higher blood pressure. The goal is to gather know…

This is the first time a new drug called CAY001 is being tested in humans. The main goal is to see if it is safe and how the body handles it. The study will give the drug to about 24 healthy volunteers at different dose levels to check for any side effects.

This is the first study testing a new oral drug called LY4515100 in humans. Researchers want to see if it's safe and how the body processes it in 40 healthy volunteers. The study involves taking the drug and staying overnight for monitoring and blood tests over about 30 days.

This study aims to understand if children with Primary Ciliary Dyskinesia (PCD) also have sensitive airways, a condition called bronchial hyperresponsiveness that's common in asthma. Researchers will test 40 children with PCD and healthy children using breathing tests and a medic…

This study aims to understand how a stroke affects the natural arm swing during walking. Researchers will measure brain activity and muscle patterns in stroke survivors and healthy people while they walk. The goal is to gather fundamental knowledge about this connection to help d…

This early-stage study aims to understand how taking sugar-based dietary supplements affects certain proteins in the immune system of healthy people. Researchers will give supplements or a placebo to 44 healthy adults and analyze their blood to see if the supplements change how i…

This study aims to understand how brain function related to learning and memory might connect adverse childhood experiences to symptoms of opioid use disorder. Researchers will compare brain scans and memory task performance across three groups: people with opioid use disorder on…

This is an early-stage study to check the safety of a new drug called LY3981314 and see how the body handles it. It involves about 76 healthy volunteers who will receive a single injection under the skin. The main goal is to identify any side effects and measure the drug's levels…

This study aims to understand how natural fluctuations in the female hormone estradiol affect the spinal cord's ability to adapt and respond to signals. Researchers will recruit 50 healthy young women and men to measure spinal cord excitability using safe, low-level electrical ne…

This is an early safety study to understand how a new drug, LY3537031, is processed by the body in people with different levels of liver function. It will enroll 32 people, including healthy volunteers and those with mild, moderate, or severe liver impairment. The main goal is to…

This study aims to understand the connection between the brain and the stomach. Researchers will use a safe, non-invasive brain stimulation technique on healthy volunteers to see how it affects electrical signals in the stomach. The goal is to map this brain-gut link and learn th…

This is the first human study of an experimental injection called ZT003. Researchers will test different doses in 76 healthy and overweight volunteers to see if it's safe and how the body processes it. The goal is to gather basic safety information to guide future studies in peop…

This study aims to create a clear set of rules for when physical therapists should check a patient's vital signs, like blood pressure and heart rate, during outpatient visits. Researchers will survey 100 experienced physical therapists over three rounds to reach agreement on whic…

This study is testing a new imaging agent called [18F]LY4214835 to see if it is safe and to measure how much radiation it delivers to different organs. It involves both healthy volunteers and people with cancer who will receive a single injection and be followed for about 35 days…

This study aims to understand how a healthy heart and metabolism function during rest and exercise across different ages. Researchers will measure heart pressures and energy use in 80 healthy volunteers using specialized catheters and scans. The goal is to create a detailed pictu…

This study aims to understand why African American adults have higher rates of heart and kidney disease. Researchers will measure kidney blood flow in 32 healthy young adults during exercise, cold exposure, and mental stress tests. The goal is to see if African American participa…

This Yale University study aims to understand how the brain changes when people with cannabis use disorder stop using it for at least four weeks. Researchers will use brain scans and memory tests to see if brain connections linked to memory improve during abstinence. The study co…

This study aims to understand how different types of exercise immediately affect the health of your blood vessels. Researchers will compare 30 minutes of rest, moderate cycling, and high-intensity interval cycling in 45 healthy and prehypertensive adults. The goal is to see which…

This study aims to measure how much of an experimental drug called olomorasib gets into the bloodstream and how long it stays there after being taken as capsules. It involves 120 healthy volunteers who will take the drug and stay overnight at a research center for monitoring. The…

This study aims to understand how a gentle, non-painful form of ear stimulation affects communication between the brain and the stomach. Researchers will use MRI scans to measure brain and stomach activity in healthy adults and people with functional dyspepsia (indigestion) while…

This study aims to understand how adding different textures to infant cereals affects how babies and toddlers chew their food. Researchers will observe 153 healthy children aged 6-24 months while they eat cereals with various textures. The goal is to learn how chewing patterns de…

This study aims to prove that prazosin capsules, a blood pressure medication, work exactly the same whether they are made at a factory in Puerto Rico or one in Italy. Healthy adult volunteers will take capsules from each location so researchers can compare how the medicine is abs…

This is a very early study to check if a new drug called IBI3032 is safe for people and to see how the body processes it. It will involve 32 healthy volunteers who will receive a single dose. The main goal is to find a safe dose and understand the drug's basic behavior in the bod…

This study is testing whether a specific probiotic supplement can help strengthen the gut lining in healthy adults. Researchers will give participants a common painkiller known to temporarily weaken the gut barrier, then measure if the probiotic helps protect it. The goal is to u…

This study looks back at existing medical records, brain scans, and genetic data from children and young adults up to age 20. The goal is to develop better computer models that can help doctors understand and predict developmental disorders. It involves analyzing information from…

This study aims to understand how different intensities of breathing muscle training affect oxygen levels in the rib muscles of healthy people. Researchers will measure muscle oxygen and blood flow before, during, and after training sessions. The goal is to gather basic knowledge…

This study is testing whether a specific type of acupuncture can make bowels move more often. Researchers are giving 30 healthy volunteers a 20-minute electroacupuncture session at two points on the body. They are using a special digital stethoscope to listen for changes in bowel…

This study aims to understand how a supplement called potassium citrate affects two natural body chemicals, oxalate and citrate, which are linked to kidney stone formation. Researchers will give the supplement to 24 people—half with a history of kidney stones and half without—and…

This early-stage study aims to understand how a drug called nirogacestat affects the way the body processes several other common medications. It will involve 16 healthy adult male volunteers who will take nirogacestat along with a specific set of test drugs. The main goal is to m…

This study aims to understand how adding natural, unpredictable timing to strength training affects the brain's control of muscles. Researchers will compare three training methods in 60 healthy adults to see which one best improves the brain's connection to muscles. The goal is t…

This is an early safety study of a new eye drop formula called BT01001. Researchers are testing three different strengths of the drops in 32 healthy adult volunteers to see how safe they are and how the body processes them. The main goal is to check for side effects and understan…

This study is testing a teacher-led program designed to help preschool children develop better social skills and reduce aggressive behavior. Researchers will follow 600 children from diverse backgrounds to see if the program decreases bullying and victimization while improving he…

This study is testing a new 20-hour training course for people who care for the elderly, focusing on how to safely feed patients who have trouble chewing or swallowing. It will enroll 150 student and professional care workers to see if the course improves their knowledge and skil…

This study aims to understand if taking the blood pressure medication losartan changes how the body absorbs and eliminates the antibiotic cephalexin. Researchers will test 12 healthy volunteers to see if taking the drugs together or spacing them apart by three hours makes a diffe…

This study is testing how well a home health kit works for people to collect their own blood samples. Researchers want to see if the kit reliably measures levels of a compound called Urolithin A, which comes from a dietary supplement called Mitopure. The goal is to understand if …

This is the first study in people for a new antibiotic called BAL2420, which is being developed to fight serious bacterial infections. Researchers are testing it in healthy volunteers to see if it is safe, how well it is tolerated, and how the body processes it. The study will gi…

This study aims to understand how a specific, ancient part of the brain helps control movement and how it might adapt to help recovery after a spinal cord injury. Researchers will observe 248 people, including both healthy volunteers and those with recent or long-standing spinal …

This early-stage study aims to see if a common antifungal medication (fluconazole) changes how much of an experimental cancer drug (olomorasib) gets into a person's blood and how long it stays there. It involves 15 healthy participants who will stay overnight at a research center…

This study is testing a new brain training method to help people reduce anxiety about future events. Healthy volunteers will try to learn to control a specific brain area using real-time feedback from an MRI scanner. The goal is to see if this training can help people feel less w…

This is the first study in people for a new drug called LTG-001. Researchers are testing its safety and how it moves through the body in healthy volunteers. The study will give the drug at different doses, both as a pill and through an IV, to see how well it is tolerated.

This is the first study in humans for a new drug called DF5112. Its main purpose is to check if the drug is safe and how the body handles it. The study will enroll 64 healthy adults who will receive either the drug or a placebo. Researchers will monitor participants closely for s…

This study aims to translate and validate a set of health questionnaires into Albanian. The goal is to create reliable tools for doctors to assess pain, mobility, and quality of life in Albanian-speaking patients with muscle or joint problems. Researchers will test these translat…

This study is testing a new, radiation-free imaging system called EIT to see how well it can show lung function in people with breathing problems. Researchers will use it on children and adults with conditions like chronic lung disease or muscle weakness, as well as healthy volun…

This study aims to develop and improve MRI scanning techniques for better image quality. Researchers are recruiting 1,000 healthy volunteers and NIH patients to undergo MRI scans lasting 20 minutes to 2 hours. The goal is to refine scanning methods that could benefit future medic…

This study aims to find out how much protein older, highly-trained cyclists need to eat after a workout to best support their recovery and training. Researchers will measure this in a small group of healthy men over 65 who cycle regularly. The goal is to gather better information…

This study aims to understand if adults who carry the gene for PKU (phenylketonuria) experience changes in brain chemistry, thinking skills, or brain activity after consuming protein. Researchers will compare 18 PKU carriers to 18 non-carriers. Participants will take a protein or…

This study aims to understand how the FDA-cleared Q-Collar device affects blood flow to the brain during rest and exercise. Researchers will compare brain blood flow in 20 healthy young adults while they wear the device versus when they don't, during activities like standing up q…

This study aims to see if drinking Bragg apple cider vinegar helps control blood sugar levels after a high-carb meal, compared to drinking water. Researchers will recruit 24 healthy adults who have slightly elevated blood sugar or related metabolic markers. Participants will take…

This study aims to understand how different areas of the healthy human brain communicate and influence each other. Researchers will use safe, non-invasive magnetic pulses and brain scans on 80 healthy adults to see if they can temporarily strengthen or weaken these connections. T…

This is a small pilot study to test a new research method. It aims to see how healthy bone marrow cells use a nutrient called glutamine for energy. The study involves 20 healthy volunteers and compares two different lab techniques. The goal is to gather basic knowledge, not to tr…

This Stanford University study aims to understand how brain activity relates to chronic low back pain. Researchers will use EEG brain scans on 130 participants with chronic back pain and healthy volunteers over several months. The goal is to identify brain patterns that might pre…

This study aims to understand if a person's natural ability to focus and control their thoughts can predict how well they learn to regulate specific brain activity using real-time MRI feedback. Researchers will enroll 40 healthy volunteers to complete mental tasks and undergo bra…

This study aims to better understand how much of certain healthy plant compounds, called flavanols, people are eating in their normal diets. Researchers will collect urine samples from 200 healthy adults to measure specific markers that show flavanol intake from foods like apples…

This study aims to understand how much energy healthy people in China burn each day. Researchers will measure 240 healthy children and adults using a precise water-tracking method and collect data on their bodies, activity, and environment. The goal is to gather accurate informat…

This is an early safety study to see how a new drug called lepodisiran behaves in people with healthy livers compared to those with mild, moderate, or severe liver problems. Researchers will give a single injection and then carefully measure how much of the drug gets into the blo…

This is the first study in humans for the experimental drug LY4088044. Researchers want to see if it's safe and how the body handles it in 104 healthy volunteers. Participants will receive injections under the skin or into a vein, and researchers will monitor them for side effect…

This study aims to collect detailed scan images of the eye from 180 people. It includes participants with various eye conditions like macular degeneration, glaucoma, and corneal diseases, as well as people with healthy eyes. The goal is to build a large database of images to help…

This is an early safety study for a new drug called BI 3776528. It will test how safe the drug is and how the body processes it in healthy male volunteers. The study will give some participants the drug and others a placebo to compare the effects.

This is the first study in humans for a new drug called SYNT-101. It aims to check the safety and how the body processes the drug in 64 healthy adults, including some who are overweight. Participants will receive either the drug or a placebo, and researchers will monitor for any …

This early-stage study aims to understand how a new oral medicine called PF-07328948 is processed by the body in people with different levels of kidney function. It will enroll 28 adults, including both healthy participants and those with moderate to severe long-term kidney impai…

This study aims to understand how different caffeinated beverages affect people's mood, energy levels, and physical responses. Researchers will recruit 150 healthy adults who regularly consume caffeine and have them try different drinks while tracking their feelings and wearable …

This study aims to understand how the body processes an omega-3 supplement called EPA, turning it into another important fat called DHA. Researchers want to see if a person's biological sex or specific genes affect how quickly this conversion happens. Healthy participants will ta…

This study aims to understand how a mild, non-invasive form of brain stimulation (tDCS) affects thinking skills like focus and self-control in healthy adults. Researchers will measure brain activity and performance on computer tasks to see if stimulating the forehead area improve…

This study is testing a new type of cooking class that teaches people how to cook with ingredients they already have, store food properly, and waste less. Researchers want to see if these skills can help adults feel less stressed and improve their diet. The study will involve abo…

This study aims to see if researchers can detect when a person is about to make a mistake during a skilled task up to one full second before it happens. Healthy right-handed adults aged 18-35 will perform typing tasks while their brain activity is monitored using special scanners…

This study aims to understand how different levels of physical fitness affect the community of bacteria living in the gut. Researchers will compare the gut bacteria of 30 healthy men, ranging from moderately active to elite athletes, by analyzing stool samples and measuring their…

This study aims to understand how the body's immune cells respond to a new type of cancer vaccine. Researchers will collect blood samples from participants to examine how immune cells recognize and potentially fight cancer cells. The research will help scientists learn how these …

This is the first study in humans to test the safety of a new inhaled drug called RB042. Researchers will give single and multiple doses to 90 healthy adults, including some who smoke, to check for side effects and see how the body handles the drug. The main goal is to determine …

This is the first study in humans for a new drug called SRK-439. It aims to check if the drug is safe and how it behaves in the body when given to healthy adults. Researchers will give different doses to small groups of volunteers to see how well it is tolerated and measure its e…

This study aims to find out if current protein recommendations for children are too low, especially for those who are very physically active. Researchers will measure protein needs in 30 healthy children aged 8-10, comparing kids who are very active to those who are more sedentar…

This study is testing a new brain training method to see if it can help people better control unwanted memories and reduce the spontaneous return of learned fear. Healthy adults will use real-time brain scan feedback to try and strengthen their brain's natural memory control netw…

This is an early-phase study to see if common heartburn medicines (famotidine/Pepcid and rabeprazole/Aciphex) change how the body processes an experimental cancer drug called nirogacestat. It will enroll 24 healthy adult men to measure drug levels and check for safety. The goal i…

This study aims to collect blood samples from 400 healthy adults to better understand how platelets work. Researchers want to learn how these blood cells contribute to inflammation and clotting in diseases. The findings may help identify new targets for future treatments for vasc…

This early-stage study aims to understand how a new medicine, PF-07328948, is processed in the bodies of people with different levels of liver impairment compared to healthy people. It will enroll 26 adults, some with stable liver disease and some without, who will take a single …

This study aims to understand if a common asthma medication (salbutamol) can improve exercise performance in non-asthmatic endurance athletes. Researchers are recruiting 64 healthy male and female runners and cyclists to test if the drug helps a specific group who experience brea…

This study aims to discover early warning signs of cancer by tracking 10,000 healthy adults for 20 years. Researchers will collect lifestyle information and blood samples from participants who are already scheduled for routine endoscopy procedures. By comparing data from people w…

This early-stage study aims to understand how a new drug, MK-2828, interacts with other common medications in the body. It involves 28 healthy participants and will measure drug levels in the blood to see if taking MK-2828 with other drugs changes how the body processes them. The…

This online study tests how well people learn from a very short animated video about stroke warning signs. 300 healthy adults and teens will watch the video and answer questions to see what they remember and if they would call for help in a stroke scenario. The goal is to see if …

This early-stage study aims to understand if a new investigational drug for heart failure (MK-2828) changes how the body processes two common medications: a cholesterol drug (rosuvastatin) and a water pill (furosemide). Researchers will give these drugs to 39 healthy participants…

This study aims to develop better brain scanning technology to understand how a normal, healthy brain works. Researchers are recruiting over 1,000 healthy adults to have detailed MRI scans while performing simple tasks. The information will help create clearer pictures of the bra…

This is an early safety study to see how healthy Chinese adults' bodies handle a single injection of an experimental drug called remternetug. The main goal is to check for any side effects and measure how much of the drug gets into the bloodstream and how long it stays. The study…

This University of Michigan study aims to understand how different personality traits and brain patterns relate to substance use behaviors in young adults. Researchers will use brain scans and behavioral tests to examine 294 participants aged 18-20. The study focuses on observing…

This study aims to understand how the bacteria in our gut might be connected to changes in the brain during normal aging and in diseases like Alzheimer's, Parkinson's, and Multiple Sclerosis. Researchers will compare 200 participants, including healthy people of different ages an…

This study aims to check the long-term safety of a dietary supplement called palmitoylethanolamide (PEA) in healthy adults. Over 200 participants will take either the supplement or a placebo daily for 12 months, with researchers closely monitoring their health for any side effect…

This is a long-term research project to learn what factors help keep our brains healthy and performing well as we age. Over 100,000 generally healthy adults will complete online brain games, questionnaires, and optional training twice a year for ten years. The goal is to gather i…

This study aims to understand how the brain learns and reasons as people grow from adolescence into adulthood. Researchers will use MRI brain scans and memory games to compare healthy teenagers (13-18) and young adults (19-25). The goal is to map how brain networks for memory and…

This is an early safety study testing a new inhaled medication called CPD704. Researchers will give single and multiple doses to 90 healthy Chinese adults to check for side effects and measure how the drug moves through the body. The main goal is to understand the drug's safety p…

This study aims to see if wearable devices can reliably measure walking problems and involuntary movements in people with Huntington's disease during their daily lives at home. Researchers will enroll 100 participants, including people with Huntington's and healthy volunteers, wh…

This early-stage study aims to understand how liver impairment affects how the body processes an experimental drug called MK-1084 (calderasib). Researchers will compare drug levels and safety in 58 participants, some with stable liver disease and some who are healthy. The goal is…

This study aims to understand how a person's genes affect their body's natural ability to stop inflammation. Researchers will analyze blood samples and health records from 200 volunteers of South Asian descent who are already part of a larger genetics program. The goal is to see …

This large research study aims to understand why some people develop serious health problems related to metabolic syndrome, like heart disease and fatty liver. Researchers will collect blood, urine, and stool samples from over 6,000 participants, both with and without metabolic s…

This is the first study in humans for a new drug called NSHO-101. Researchers want to see how the drug moves through the body and check for any side effects. The study will involve 24 healthy volunteers to gather this initial safety information.

This study aims to learn about the normal communities of bacteria (microbiome) in the vagina and mouth, and how they might interact. Researchers will collect swab samples from 520 healthy women and some Pap smears to understand this relationship and the impact of HPV. The goal is…

This study is testing whether video calls (telemedicine) are a practical way to help people considering donating a kidney. Researchers want to see if remote education and counseling helps potential donors make more confident decisions. They will compare video visits to standard i…

This study is testing whether a 21-day self-guided phone app can help prepare people for a psychedelic experience. Forty healthy volunteers will use either a meditation or a music-listening version of the app, then have a supervised psilocybin session. The main goal is to see if …

This study aims to understand how HIV affects the brain's connections, even when the virus is controlled by medication. Researchers will use special brain scans (PET and MRI) and memory tests on 70 people—some with well-controlled HIV and some without HIV—over two years. The goal…

This early-stage study aims to understand how eating food and taking a common stomach acid medication (rabeprazole) affect how the body absorbs a new drug called VRN110755. It involves 24 healthy adult volunteers who will take the drug under different conditions: on an empty stom…

This study aims to understand how the brain's reward system works by mapping 'optimistic' and 'pessimistic' signals. Researchers will compare brain scans of 140 people, including healthy participants and those with Parkinson's disease, while they play a simple money game. The goa…

This study aims to see if drinking an olive extract supplement (OliPhenolia®) for 8 days helps healthy, active people burn more fat while cycling. Researchers also want to know if having caffeine before a workout boosts this effect. They will measure fat burning by analyzing part…

This is a very early study to check the safety of a new drug called HY8931 and see how the body processes it. It will involve 60 healthy adults who will receive either the drug or a placebo (a dummy treatment) as a single injection or several injections over time. The main goal i…

This is an early safety study testing a new drug called HB0056 for the first time in healthy people. Researchers will give single doses to 46 healthy adults to check for side effects and see how the body processes the drug. The main goal is to determine if HB0056 is safe enough t…

This study is testing whether taking a daily carotenoid supplement (like those found in carrots and leafy greens) can improve eye health and memory in healthy adults. Researchers will measure changes in the retina's protective layer, blood flow, vision clarity, and working memory…

This study is testing a community workshop designed to teach people how to organize local actions to help reduce the impact of cancer in their area. Researchers want to see if the workshop is practical, well-received, and what kinds of plans participants create. The goal is to em…

This is the first study in people for a new drug called CM383. It will test how the body processes the drug and check for side effects in 30 healthy men. The drug will be given as a single dose, either through an IV or an injection under the skin.

This is the first study in people for a new drug called Epaminurad. It aims to see how the drug moves through the body and if it is safe. The study involves 34 healthy adult volunteers who will take a single dose while fasting.

This is a very early safety study for a new substance used in PET scans, a type of medical imaging. Researchers are testing it in 10 healthy adults to see how it moves through the body and to check for any side effects. The goal is to gather basic safety information so that in th…

This study aims to understand how the brain and gut hormones work together to make you feel full or hungry. Researchers will measure brain activity and hormone levels in 15 healthy volunteers after they experience different types of food or stomach sensations. The goal is to crea…

This is an early safety study for a potential new medicine called PF-07985631, which is being developed to treat a serious kidney disease called IgA nephropathy. The study will give single injections of the drug to healthy adult volunteers to check for side effects and see how th…

This study aims to understand how a person's mental focus during leg strength training affects their walking patterns and related brain activity. Researchers will enroll 45 healthy older adults to compare different mental focus strategies during calf muscle exercises. The goal is…

This study is testing new wearable sensors that stick to the skin to measure vital signs like heart rate and breathing. Researchers want to see if these sensors are comfortable, safe, and work as well as standard medical equipment. Healthy volunteers will wear the sensors during …

This study aims to understand if taking a specific probiotic can help maintain healthy gut bacteria in people using common acid reflux medications (PPIs). Researchers will enroll 30 healthy adults to see if the probiotic prevents medication-related changes to the microbes in thei…

This is a very early study to check if a new drug called LY4066708 is safe for people and to see how the body handles it. It will involve about 104 healthy volunteers who will receive the drug and be monitored for up to 24 weeks. The main goals are to identify any side effects an…

This study aims to understand how a natural fiber from chicory root affects the gut bacteria of healthy adults. Researchers will give 52 participants either the chicory inulin fiber or a placebo powder for 6 weeks, then track changes in their gut bacteria, bowel habits, and mood …

This study aims to better understand how Alzheimer's disease and Lewy body disease affect the brain over time. Researchers will observe 90 participants—including people with these conditions and healthy individuals—using brain scans, memory tests, and measurements of brain wave a…

This study aims to understand if a nasal spray containing oxytocin changes how healthy people react to threats. Participants will play a virtual game where they must escape from a predator while researchers measure their brain activity, skin sweat, and decisions. The goal is to l…

This study aims to collect heart function data from healthy adults to serve as a comparison group for research on congenital heart disease. Researchers need 50 healthy participants who can undergo MRI scans and heart pressure measurements. The data will help doctors better unders…

This study aims to understand how a safe, mild form of electrical brain stimulation affects how people think and process information. Researchers will compare healthy younger adults (20-40) and older adults (60-80) as they do computer tasks, using MRI scans to see how their brain…

This is the first study in people for a new drug called AZD1613, made by AstraZeneca. It aims to check if the drug is safe, how the body handles it, and what it does in healthy volunteers, including people of Chinese and Japanese descent. The study will give the drug at different…

This study is testing whether a type of safe, non-invasive brain stimulation can help experienced meditators quickly reach a deep, calm state where they feel less attached to their own thoughts and feelings. Researchers will compare two stimulation techniques on 12 healthy, exper…

This study aims to understand how having a higher body weight affects the heart and blood vessels during breathing exercises and short bouts of exercise. Researchers will measure blood pressure in 80 adults while they perform specific breathing tasks and light exercise. The goal …

This is a first-in-human study to check the safety and see how the body processes a new drug called HY6725. It will involve 74 healthy adults who will receive either the drug or a placebo (an inactive substance) through injections under the skin. The main goal is to see if the dr…

This is an early safety study to understand how healthy people tolerate a new experimental drug called LY3867070. Researchers will give the drug to 196 healthy volunteers and monitor for side effects while measuring how the body processes it. The study will also check how the dru…

This study aims to understand if brain inflammation is linked to chronic pain and fatigue in conditions like fibromyalgia, chronic fatigue syndrome, and multiple sclerosis. Researchers will use a special brain scan to measure inflammation levels in 120 participants, comparing peo…

This early-stage study aims to understand how a common heart medication (diltiazem) changes the way the body processes an experimental cancer drug (nemtabrutinib). Researchers will measure drug levels in the blood of 24 healthy participants who take nemtabrutinib with and without…

This study aims to understand if weakness in the big toe is linked to the severity of nerve damage caused by chemotherapy, a common side effect. Researchers will test a new, portable device called the ToeScale to measure toe strength in about 30 people with this nerve damage and …

This study is testing a new swallowable capsule that measures temperature inside the digestive tract. The goal is to see if this 'thermal capsule' can collect useful data that might one day help doctors spot diseases like Crohn's. Researchers are enrolling 10 healthy adults to sw…

This study aims to understand how eating berries changes tiny particles in the body called extracellular vesicles, which act as cell messengers. Healthy adults will eat a daily serving of cloudberries or lingonberries for one week. Researchers will collect samples to see if the b…

This study is testing new MRI scanning methods to see if they can improve image quality and speed during MRI-guided surgical procedures. Researchers are enrolling 100 healthy volunteers or patients already scheduled for MRI-guided procedures. The goal is to determine if this new …

This study aims to understand what harmful chemicals firefighters absorb when fighting building fires. Researchers will collect urine and cheek cell samples from 60 firefighters before a fire call, then again within 24 hours and one week after. By comparing these samples, they ho…

This study aims to understand how a mother's daily patterns of sitting, physical activity, and sleep during pregnancy might influence her child's growth and future risk for obesity and heart problems. Researchers will follow 800 mother-child pairs, using activity monitors during …

This is an early-stage study to check the safety and how the body processes a new drug called BI 3031185. It will involve 60 healthy male volunteers who will take the drug or a placebo for a period of time. The main goal is to see how well the drug is tolerated and to measure its…

This study aims to better understand how much food a person needs to eat to match the energy their body burns, a state called 'energy balance.' Researchers will use special sealed rooms (whole-room calorimeters) to precisely measure the energy burned by 34 healthy participants. T…

This study aims to understand if a gentle ear nerve stimulation can help people better remember and benefit from insights gained during a guided psilocybin experience. Researchers will enroll 108 healthy adults who feel their wellbeing could be better. They will test if the nerve…

This is a small, early-stage study to test a new procedure for measuring how the hormone insulin works in the body. Researchers want to understand how much insulin is actually needed to keep blood sugar normal. They will test this new method, called a Graded Insulin Suppression T…

This study aims to understand how eating white potatoes (like fries or baked potatoes) at breakfast versus dinner affects your blood sugar, feelings of fullness, and how much you eat later. Researchers will measure these effects in 30 healthy adults by having them eat different t…

This study aims to understand how brain connections differ in people with schizophrenia or cannabis use disorder compared to healthy people. Researchers will use a special brain scan (PET imaging) to measure these connections in 250 adults aged 18-65. The goal is to gather knowle…

This study aims to develop better MRI scanning methods to see the heart and arteries in more detail without using radiation. Researchers will compare these new MRI techniques to standard heart tests in up to 4000 adults, including both healthy volunteers and people with or at ris…

This study aims to understand why people have different blood sugar responses to the same foods. Researchers will use continuous glucose monitors to track how 100 participants with varying health statuses react to meals like rice, testing if adding things like fiber or vinegar he…

This study aims to see if two different auto-injector devices deliver the same amount of an investigational drug called tulisokibart into the body. Researchers will measure drug levels in the blood and check for side effects in healthy participants. The goal is to understand if t…

This early-stage study aims to understand if an investigational drug called SP-624 changes brain activity patterns in healthy adults and people with major depression. Researchers will use a special cap to measure brain waves and AI software to analyze them. The study will also ch…

This study aims to understand the earliest communication between a mother and a newly formed embryo. Researchers are following healthy women trying to get pregnant, collecting daily samples like saliva and blood to see how the body signals change. By comparing cycles that lead to…

This study aims to understand how eczema (atopic dermatitis) and food allergies might be connected biologically. Researchers will collect blood and skin samples from 200 people with different combinations of these conditions and healthy volunteers. The goal is to create a 'molecu…

This study aims to understand how growth hormone affects the cells that produce insulin in women who had high blood sugar during pregnancy (gestational diabetes). Researchers will compare 30 women with a past history of gestational diabetes to a control group without that history…

This study aims to understand the immediate effects of a single weight training session, with and without added stretching, on heart and blood vessel function. Researchers will measure blood pressure and artery dilation in 27 healthy men after they complete different exercise rou…

This study is testing a new, swallowable pill designed to collect samples of bacteria from deep inside the gut, especially the small intestine. Ten healthy volunteers will swallow the pill to see if it's safe, comfortable, and can collect better samples than regular stool tests. …

This study aims to understand if a specific enzyme linked to brain inflammation is higher in people with Alzheimer's disease or mild cognitive impairment. Researchers will use special brain imaging scans (PET and MRI) on 90 participants aged 50 and older, including those with the…

This early-stage study is testing a new radioactive tracer for brain and body scans in 40 healthy volunteers. The tracer is designed to attach to a specific brain protein (PDE4D) that researchers believe plays a role in depression and Alzheimer's disease. The goal is to see if th…

This study aims to develop and test a new, non-invasive method for stimulating the brain using focused ultrasound. Researchers will use brainwave recordings (EEG) to guide the ultrasound in real-time, creating a 'closed-loop' system. The goal is to better understand how this stim…

This study is testing whether a specific diet low in the nutrient methionine can change the bacteria in your gut and reduce inflammation in the body. It involves 40 healthy adults who will follow the special diet for short periods while researchers check their stool, blood, and i…

This is an early-stage study to check the safety and side effects of a new injectable drug called LY3971297. It will involve about 225 healthy adults and adults with obesity, high blood pressure, or reduced kidney function. The main goal is to see how the body handles the drug an…

This study aims to understand how different caffeinated beverages affect people's mood, energy, and sleep patterns. Researchers will recruit 75 healthy adults who regularly drink caffeinated beverages. Participants will try different drinks while tracking their feelings and physi…

This study aims to understand how two different types of real-time brain scan feedback affect a specific brain area linked to feelings and empathy. Researchers will recruit 90 healthy volunteers to compare continuous feedback with intermittent feedback. The goal is to see which m…

This study is testing a new tool to help people understand medical information. Researchers want to see if a friendly, animated character that explains medical illustrations works better than letting people read the information on their own. They are comparing the animated charac…

This study is testing whether using AI chatbots like ChatGPT can help train physical therapy students to think like clinicians. About 200 third-year students will be split into two groups: one will practice solving patient cases with an AI, while the other uses standard teaching …

This study aims to understand how adding electrical muscle stimulation (EMS) to cycling affects how hard exercise feels and people's energy levels. Researchers will compare arm cycling to leg cycling in 120 healthy, active young adults to see if EMS changes perceptions of effort.…

This study aims to understand how a single dose of psilocybin, the compound in psychedelic mushrooms, changes how people think and how their brains work. Researchers at Johns Hopkins will give 30 healthy volunteers a moderate dose or a placebo and measure their brain activity, cr…

This is the first study to test a new oral drug called SUVN-I6107 in people. It aims to check if the drug is safe, how the body processes it, and if it affects brain activity in healthy volunteers. The study involves giving single and multiple doses to up to 64 healthy adults and…

This study aims to understand how temporal lobe epilepsy affects long-term spatial memory, like remembering a route. Researchers will compare how 37 people with epilepsy and healthy volunteers perform on a navigation task after learning it, testing their memory again one hour and…

This study is comparing two types of lasers used for skin treatments to see which one is better for patients. Researchers want to know if a newer laser (called DFG) causes less pain and allows the skin to heal faster than the commonly used CO2 laser. They are testing this on the …

This study aims to understand how the brain processes emotions and thoughts in both healthy people and those with depression. Researchers will use brain scans and gentle magnetic stimulation while participants do computer tasks. The goal is to gather information that could lead t…

This study aims to understand how non-invasive brain stimulation can improve hand movement control in healthy older adults. Researchers will compare standard stimulation with personalized, targeted stimulation to see which works better for tasks like pegboard tests and precision …

This study aims to understand if adding rhythmic sound—like a metronome beat or music—to specific eye-head coordination exercises can improve the reflex that keeps vision clear when you move your head. Researchers will compare three conditions: exercises in silence, with a metron…

This is an early safety study to understand how a new drug, LY3537031, moves through and leaves the body. It will compare people with healthy kidney function to those with severe kidney impairment or kidney failure. The main goal is to measure drug levels in the blood and check f…

This study aims to understand how early blood changes might predict progression to multiple myeloma, a serious blood cancer. Researchers are enrolling 2,000 healthy adults who have close relatives with blood cancers to track them over time. The goal is to identify warning signs t…

This study is testing whether gentle brain stimulation can help people who have never meditated before quickly reach a calm, focused state similar to what experienced meditators achieve. Researchers will use a special cap to measure brain activity while participants try a simple …

This study aims to understand how exercise affects hunger and eating. Researchers will compare a short 10-minute run, a longer 30-minute run, and no exercise in healthy men. They will measure hunger feelings, hormone levels, and how much food participants eat afterward to see if …

This study aims to understand how blood flow in fat tissue differs between younger and older healthy adults. Researchers will compare 24 participants aged 18-35 with those aged 65-80, measuring blood flow before and after drinking a sugary drink and taking small fat tissue sample…

This study aims to understand if there is a connection between heavy social media use and compulsive exercise behaviors in university students. Researchers will survey 187 healthy students aged 18-24 who use social media for at least 4 hours daily. The goal is to gather insights …

This early-stage study aims to understand how liver problems affect how much of a new drug, BI 1291583, gets into a person's bloodstream. The drug is being developed to treat bronchiectasis, a chronic lung disease. Researchers will compare blood levels in 32 adults with varying d…

This is an early-stage study to understand how a new drug, called DA-1229_01, is processed by the body and to check its safety. It involves 40 healthy volunteers who will take a single dose while fasting. The main goal is to measure the drug's levels in the blood over time and se…

This study aims to find biological signs in the brain and genes that can predict if a person's depression will return after they stop taking antidepressant medication. Researchers will follow 204 people with depression and healthy volunteers, measuring brain activity and taking b…

This study aims to understand how the brain responds to a non-invasive stimulation technique (TMS) to potentially improve treatments for arm and hand movement problems after a stroke. Researchers are testing if timing the stimulation to match a person's natural brainwave patterns…

This is the first study to test a new drug called MORF-440 in people. It will enroll 80 healthy volunteers to check if the drug is safe and how the body handles it. Researchers will give different doses to small groups and closely monitor for any side effects.