Could immune cells in fat hold the key to Obesity-Related disease?
NCT ID NCT06571474
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This study is investigating how immune cells called macrophages in fat tissue handle fat and influence metabolism. Researchers will compare people with obesity and related metabolic issues to lean individuals, using imaging, blood tests, and tissue biopsies. The goal is to understand why some people with obesity develop conditions like type 2 diabetes and fatty liver disease, which could lead to new prevention or treatment strategies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- No drug or treatment is being tested. The study observes immune cells in fat and muscle tissue.
- What this could lead to
- If this research succeeds, it could point toward new ways to treat obesity-related conditions like type 2 diabetes and fatty liver disease by targeting immune cells in fat tissue.
- What could go wrong
- This is an observational study, so it won't directly test a treatment. It may not lead to immediate therapies, and findings might not apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DIABETES MELLITUS, TYPE 2 are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Missouri School of Medicine
RECRUITINGColumbia, Missouri, 65212, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new stomach and gut bypass surgery tackle obesity and diabetes?
- Could a new oral drug change future treatments? early safety trial begins
- Can brain scans unlock the secret to hearing in crowded rooms?
- Can a Light-Guided device make arterial sticks easier?
- Water workouts could be the key to back pain relief
- Can a Two-Drug combo tip the scales against obesity?