Chicory fiber study seeks to unlock secrets of gut microbe changes

NCT ID NCT06528041

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how a prebiotic fiber from chicory root (inulin) changes gut bacteria in healthy adults aged 18-45. Over 13 weeks, participants take either inulin or a placebo (maltodextrin) and provide stool and blood samples. Researchers track changes in Bifidobacterium and other gut microbes, along with bowel habits, mood, and appetite. The goal is to understand why people's gut bacteria respond differently to the same fiber.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

chicory inulin (a prebiotic fiber supplement)

What this could lead to

If successful, this study could reveal how individuals respond differently to prebiotic fiber, helping personalize dietary recommendations for gut health.

What could go wrong

This is an early-stage, small study (52 healthy adults) focused on measuring changes, not treating a disease. Results may not apply to people with health conditions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Purdue University

    RECRUITING

    West Lafayette, Indiana, 47907, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••