Chicory fiber study seeks to unlock secrets of gut microbe changes

NCT ID NCT06528041

Recruiting now Knowledge-focused Sponsor: Purdue University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how a prebiotic fiber from chicory root (inulin) changes gut bacteria in healthy adults aged 18-45. Over 13 weeks, participants take either inulin or a placebo (maltodextrin) and provide stool and blood samples. Researchers track changes in Bifidobacterium and other gut microbes, along with bowel habits, mood, and appetite. The goal is to understand why people's gut bacteria respond differently to the same fiber.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: chicory inulin (a prebiotic fiber supplement)
What this could lead to: If successful, this study could reveal how individuals respond differently to prebiotic fiber, helping personalize dietary recommendations for gut health.
What could go wrong: This is an early-stage, small study (52 healthy adults) focused on measuring changes, not treating a disease. Results may not apply to people with health conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY

Contacts and locations

Locations

Purdue University
RECRUITING

West Lafayette, Indiana, 47907, United States

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