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Liver function may change how new lung drug works

NCT ID NCT07023354

Recruiting now Knowledge-focused Sponsor: Boehringer Ingelheim Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how a single dose of the experimental drug BI 1291583 behaves in the blood of people with and without liver problems. The drug is being developed for bronchiectasis, a chronic lung disease. About 32 adults aged 18–80 will take part, divided into groups based on liver function. The goal is to see if liver impairment changes drug levels, which helps doctors decide on safe dosing.

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Conditions

The condition(s) this trial relates to.

liver disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY HEPATIC IMPAIRMENT

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • American Research Corporation at the Texas Liver Institute

    RECRUITING

    San Antonio, Texas, 78215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Orlando Clinical Research Center

    RECRUITING

    Orlando, Florida, 32809, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tranquil Clinical Research

    COMPLETED

    Houston, Texas, 77598, United States

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Other studies related to the condition(s) this trial covers.