Shout it out: can growls and screams raise pain tolerance?

NCT ID NCT04425395

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time

Summary

Researchers want to know whether making non-verbal sounds such as shouting, growling, or screaming changes how long a person can tolerate pain. Healthy adults place a hand in cold water and keep it there as long as they can, up to five minutes, while researchers measure how quickly they pull away and how intense the pain feels. The study compares trials with and without vocalisations to see if the sounds affect pain tolerance.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Making non-verbal sounds such as shouting, growling, or screaming during a cold-water pain test
What this could lead to
If the sounds change pain tolerance, this could point to simple vocal techniques that help people cope with brief painful procedures.
What could go wrong
The study is small and uses healthy adults in a lab setting, so any effect may not carry over to real medical pain. The cold-water task is uncomfortable but stops before harm.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 104 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2022

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participant in good health * Affiliated or entitled participant in a social security scheme * Participant who has received informed information about the study and has co-signed a consent to participate in the study with the investigator. Exclusion Criteria: * Chronic pain * High blood pressure or poor circulation * Cardiac or vascular disease, or a heart condition (including symptoms of Raynaud's syndrome) * Allergy or hypersensitivity to cold * Diabetes * Epilepsy * Pregnancy * Recent serious injury * Neurological or psychiatric condition known to affect pain tolerance (e.g., peripheral neuropathy, schizophrenia) * History of fainting or seizures * History of frostbite * Chronic smoker (more than 10 cigarettes a day)

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Healthy are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Centre Hospitalier Universitaire Saint-Etienne

    RECRUITING

    Saint-Etienne, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.