Shout it out: can growls and screams raise pain tolerance?
NCT ID NCT04425395
First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time
Summary
Researchers want to know whether making non-verbal sounds such as shouting, growling, or screaming changes how long a person can tolerate pain. Healthy adults place a hand in cold water and keep it there as long as they can, up to five minutes, while researchers measure how quickly they pull away and how intense the pain feels. The study compares trials with and without vocalisations to see if the sounds affect pain tolerance.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Making non-verbal sounds such as shouting, growling, or screaming during a cold-water pain test
- What this could lead to
- If the sounds change pain tolerance, this could point to simple vocal techniques that help people cope with brief painful procedures.
- What could go wrong
- The study is small and uses healthy adults in a lab setting, so any effect may not carry over to real medical pain. The cold-water task is uncomfortable but stops before harm.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 104 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
May 2022
- Expected to finish
-
Dec 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 60 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participant in good health * Affiliated or entitled participant in a social security scheme * Participant who has received informed information about the study and has co-signed a consent to participate in the study with the investigator. Exclusion Criteria: * Chronic pain * High blood pressure or poor circulation * Cardiac or vascular disease, or a heart condition (including symptoms of Raynaud's syndrome) * Allergy or hypersensitivity to cold * Diabetes * Epilepsy * Pregnancy * Recent serious injury * Neurological or psychiatric condition known to affect pain tolerance (e.g., peripheral neuropathy, schizophrenia) * History of fainting or seizures * History of frostbite * Chronic smoker (more than 10 cigarettes a day)
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Healthy are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Centre Hospitalier Universitaire Saint-Etienne
RECRUITINGSaint-Etienne, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a protein powder with creatine and fiber boost everyday Well-Being?
- Green tech or hidden stress? bus Drivers' hearts monitored behind the wheel
- Scientists probe why brain stimulation works for some and not others
- Tiny doses, big questions: how does the body handle this prodrug?
- First human test of CM583: can this biologic pass the safety check?
- Scientists map how noise blurs speech across frequencies