New imaging agent could help spot hidden infections

NCT ID NCT07110519

Recruiting now Knowledge-focused Sponsor: St. Jude Children's Research Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase study tests a new radioactive tracer called [18F]-fluoromannitol in 10 healthy adults. The tracer is designed to light up infections on PET scans. Researchers will check its safety and how it spreads through the body. If all goes well, it may later be tested in people with sickle cell disease, cancer, or joint implants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: [18F]-fluoromannitol (a radioactive tracer for PET scans)
What this could lead to: If successful, this tracer could help doctors spot infections in people with sickle cell disease, cancer, or joint implants using PET scans.
What could go wrong: This is a very early (Phase 0) study with only 10 healthy people. It only checks safety and distribution, not whether it works for diagnosis. The tracer may not perform well in later studies.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY

Contacts and locations

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Locations

St. Jude Children's Research Hospital
RECRUITING

Memphis, Tennessee, 38105, United States

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