Brain wave test may predict ketamine success for severe depression

NCT ID NCT06480201

First seen Feb 01, 2026 · Last updated Jun 13, 2026 · Updated 17 times

Summary

This study looks at whether specific brain wave patterns (gamma oscillations) can help predict how well ketamine therapy works for people with treatment-resistant depression. Researchers will measure brain activity using EEG before and during ketamine treatment and track depression symptoms over four weeks. The goal is to find a simple brain-based marker that could guide personalized treatment decisions for those who haven't benefited from other antidepressants.

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Contacts and locations

Locations

  • Texas A&M (Houston Methodist Hospital Location)

    Houston, Texas, 77030, United States

  • Wells Medicine

    Houston, Texas, 77024, United States

Conditions

Explore the condition pages connected to this study.