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Could a daily probiotic help you feel fuller and eat less?

NCT ID NCT07715955

Recruiting now Disease control Sponsor: Maastricht University Medical Center Source: ClinicalTrials.gov ↗

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This study investigates whether a 16-week course of a probiotic supplement can increase feelings of fullness (satiety) and alter the composition of gut bacteria in healthy adults aged 20–70 with a BMI of 25 or higher. Participants take either the probiotic or a placebo daily and visit the research center three times for blood draws, stool samples, and food questionnaires. The main goal is to see if the probiotic reduces how much people eat when given free access to food.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a probiotic supplement containing multiple bacterial strains
What this could lead to
If it works, this could point toward a natural, side-effect-free way to help people feel fuller and eat less, aiding weight management.
What could go wrong
This is an early-stage study with a modest sample size. The effect on satiety may be small or not clinically meaningful, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADULTS FEMALE GUT MICROBIOTA MODULATION HEALTHY MALE OVERWEIGHT (BMI > 25) OVERWEIGHT , OBESITY SATIETY AND FOOD INTAKE

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Maastricht University, Department of Nutrition and Movement Sciences

    RECRUITING

    Maastricht, Limburg, 6200MD, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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