Maastricht University Medical Center

This study is testing whether giving critically ill ICU patients a higher amount of protein through their feeding tube can help their bodies build and maintain muscle better than a standard amount. Researchers will compare two protein levels in 26 patients who are on a ventilator…

This early-stage trial is testing a new drug called CP-506 in adults with advanced solid tumors that have spread or are hard to treat. The study aims to find a safe dose and see if the drug, given alone or with other standard cancer treatments, can shrink tumors. It will enroll u…

This study is investigating whether exercising in the afternoon is more effective than morning exercise at improving blood sugar control in people with pre-diabetes. Researchers will enroll 24 overweight adults to complete a 12-week high-intensity interval training program, assig…

This large study is testing whether using a person's genetic information can help doctors prescribe psychiatric medications more effectively. It will compare standard prescribing against a method that uses genetic test results to guide drug choice and dosage. The goal is to see i…

This study is testing if patients who receive a modern cornea transplant can safely use a weaker steroid eye drop and stop it sooner. It aims to prevent the body from rejecting the new cornea while reducing the common side effect of high eye pressure, which can damage vision. Res…

This study is testing whether a surgical procedure called lymphaticovenous anastomosis (LVA) is better than a sham (fake) surgery at reducing chronic limb swelling (lymphedema) in cancer survivors. It will involve 110 participants who have swelling that hasn't improved with stand…

This study is testing whether a newer type of PET scan (using a tracer called 68Ga-FAPI-46) is better at finding where estrogen-positive breast cancer has spread compared to the standard scan (18F-FDG). Researchers will enroll 20 women with this type of breast cancer to see if th…

This study is testing whether cancer can be reliably detected through a simple blood draw instead of more invasive tissue biopsies. Researchers will collect blood samples from 40 adults newly diagnosed with breast, colorectal, lung, or brain cancer. They aim to measure cancer DNA…

This study is testing a new laboratory method called the 'HMEC test' to better diagnose the underlying cause of a rare and severe condition called thrombotic microangiopathy (TMA). TMA causes dangerous blood clots in small vessels, often damaging the kidneys and brain. Researcher…

This study is testing if a personalized diet plan works better than standard healthy eating advice to prevent type 2 diabetes. Researchers will enroll 240 overweight adults and use a computer model to group them by their metabolism and body type. One group will get a diet custom-…

This study aims to better understand how much energy critically ill patients use while in the hospital. Researchers will use a special, non-invasive water test on 50 adult ICU patients to measure their energy burn over time. The goal is to gather more accurate information to help…

This study aims to understand if eating wild blueberries over time can improve brain health in older adults. Researchers will measure changes in brain blood flow, how the brain responds to insulin, and performance on memory and thinking tests. The goal is to learn more about how …

This study aims to understand how a ketone supplement drink affects the way trained cyclists use carbohydrate energy during a long workout. Researchers will compare athletes taking carbs with the ketone supplement against those taking carbs with a placebo drink. The goal is to ga…

This study is building a large collection of genetic samples and health information from patients visiting a genetics clinic. The goal is to store this 'biobank' for future scientists to study, helping them discover how genes work and find new treatment possibilities down the roa…

This study aims to understand whether a week of daily exercise or a week of calorie restriction is better at slowing prostate tumor growth while preserving muscle in men with prostate cancer. Researchers will measure protein changes in tumor and muscle tissue after the 7-day inte…

This study aims to understand if taking a special ketogenic supplement drink every evening for four weeks changes how the body burns fuel at night. It will involve 14 healthy but overweight, sedentary adults aged 60-80. Researchers will compare the supplement's effects on metabol…

This study aims to understand how often people with liver cirrhosis see doctors and get medical scans, and what factors influence their healthcare use. Researchers will look back at the medical records of 600 adult patients with liver cirrhosis from multiple hospitals. The goal i…

This study aims to find out if taking walking breaks while sitting for long periods can improve mental sharpness and blood sugar control. Researchers will test four different patterns of breaks with 33 young, inactive adults. The goal is to gather knowledge about which break patt…