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Your metabolism may hold the key to preventing diabetes

NCT ID NCT06923644

Recruiting now Prevention Sponsor: Maastricht University Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a diet tailored to a person's unique metabolism (called a 'metabotype') can prevent type 2 diabetes better than standard healthy eating advice. Overweight or obese adults at risk for diabetes will follow either a personalized or standard diet for 12 months. The goal is to see if the personalized approach improves insulin sensitivity and blood sugar control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
personalized diet
What this could lead to
If it works, this could show that tailoring diets to a person's metabolism is a better way to prevent type 2 diabetes than standard dietary advice.
What could go wrong
This is an early-stage study with only 240 people, so results may not apply to everyone. The personalized diet may not be more effective than standard guidelines, and sticking to any diet for a year is hard.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

glucose intolerance Insulin Resistance Obesity obesity disorder Overweight prediabetes syndrome type 2 diabetes mellitus prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY AND OVERWEIGHT PRE DIABETIC TYPE 2 DIABETES MELLITUS (T2DM)

Contacts and locations

Locations

  • Maastricht University Medical Center, Department of Human Biology, NUTRIM Institute of Nutrition and Translational Research in Metabolism

    RECRUITING

    Maastricht, 6200MD, Netherlands

  • Wageningen University and Research, Division of Human Nutrition

    RECRUITING

    Wageningen, 6700AA, Netherlands

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