A scent of citrus: could bitter orange oil ease fatigue and aid sleep in diabetes?

NCT ID NCT07756151

Not yet recruiting Symptom relief Sponsor: Uludag University Source: ClinicalTrials.gov ↗

First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time

Summary

This trial tests whether inhaling bitter orange oil before bed can improve sleep quality and reduce fatigue in adults with type 2 diabetes. One hundred participants will be randomly assigned to inhale either bitter orange oil or plain water for three nights. On the fourth morning, researchers will measure sleep quality, fatigue levels, and blood sugar to see if the citrus scent makes a difference.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bitter orange oil inhalation aromatherapy
What this could lead to: If effective, this simple, drug-free aromatherapy could offer a low-cost way to help people with type 2 diabetes sleep better and feel less tired.
What could go wrong: This is a small, short-term trial (three nights) with a subjective outcome. Results may not apply broadly, and the effect could be due to placebo or the ritual of inhalation.

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Conditions

The condition(s) this trial relates to.

Fatigue insomnia type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE 2 DIABETES MELLITUS (T2DM)

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Other studies related to the condition(s) this trial covers.