Could a two-vein embolization trick turn inoperable liver tumors into operable ones?
NCT ID NCT07717437
First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time
Summary
This international registry collects medical images and health data from people with liver cancer or liver metastases who received a procedure called combined portal and hepatic vein embolization (PVE/HVE). The procedure blocks two sets of veins in the liver to encourage the healthy part to grow larger, potentially making surgery possible for tumors that were previously too risky to remove. Researchers aim to identify which patients benefit most and how safe the technique is.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- combined portal and hepatic vein embolization (PVE/HVE)
- What this could lead to
- If the data show that PVE/HVE reliably makes more liver tumors removable, this technique could become a standard step before surgery for people with initially unresectable liver cancer.
- What could go wrong
- This is an observational registry, not a controlled trial, so it can only suggest associations, not prove the technique works. Results depend on the quality and completeness of data from many hospitals.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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Aintree University Hospital
RECRUITINGLiverpool, Merseyside, L9 7AL, United Kingdom
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Amsterdam UMC
RECRUITINGAmsterdam, North Holland, 1105 AZ, Netherlands
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Auckland City Hospital
RECRUITINGGrafton, Auckland, 1023, New Zealand
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CHU de Liège
RECRUITINGLiège, Liège, 4000, Belgium
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
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Erasmus Hospital
RECRUITINGAnderlecht, Brussels Capital, 1070, Belgium
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Erasmus MC
NOT_YET_RECRUITINGRotterdam, South Holland, 3015 GD, Netherlands
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Hospital Universitari Germans Trias i Pujol
RECRUITINGBadalona, Barcelona, 08916, Spain
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Juravinski Hospital and Cancer Centre
RECRUITINGHamilton, Ontario, L8V 5C2, Canada
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Karolinska University Hospital
RECRUITINGStockholm, Stockholm County, 17176, Sweden
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Klinik Hirslanden
RECRUITINGZurich, Canton of Zurich, 8032, Switzerland
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Klinikum Saarbrücken
RECRUITINGSaarbrücken, Saarland, 66119, Germany
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Leids Universitair Medisch Centrum
RECRUITINGLeiden, South Holland, 2333, Netherlands
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MUMC+
RECRUITINGMaastricht, Limburg, 6229HX, Netherlands
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
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McGill University Health Centre
RECRUITINGMontreal, Quebec, H3G 1A4, Canada
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MedUni Wien
RECRUITINGVienna, State of Vienna, 1090, Austria
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Monash Medical Centre
RECRUITINGClayton, Victoria, 3168, Australia
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Newcastle upon Tyne Hospitals
RECRUITINGNewcastle upon Tyne, North East England, NE7 7DN, United Kingdom
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Oslo University Hospital
RECRUITINGOslo, Oslo, 0424, Norway
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Queen Elizabeth Hospital
RECRUITINGBirmingham, West Midlands, B15 2GW, United Kingdom
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Rush University Medical Center
RECRUITINGChicago, Illinois, 60612, United States
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Social Center South (Klinik Favoriten)
RECRUITINGVienna, State of Vienna, 1100, Austria
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The Ottawa Hospital
RECRUITINGOttawa, Ontario, K1H 8L6, Canada
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UZ Antwerpen
RECRUITINGEdegem, Antwerpen, 2650, Belgium
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UZ Gent
RECRUITINGGhent, Oost-Vlaanderen, 9000, Belgium
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Universitair Medisch Centrum Groningen
RECRUITINGGroningen, Provincie Groningen, 9713 GZ, Netherlands
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University Hospital Aachen (Uniklinik RWTH Aachen)
RECRUITINGAachen, North Rhine-Westphalia, 52074, Germany
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University Hospital Linköping
RECRUITINGLinköping, Östergötland County, 581 85, Sweden
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Universitätsklinikum Halle
RECRUITINGHalle, Saxony-Anhalt, 06120, Germany
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Vall d'Hebron University Hospital
RECRUITINGBarcelona, Barcelona, 08035, Spain
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