New drug targets hidden tumor weakness in Hard-to-Treat cancers
NCT ID NCT04954599
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is for adults with solid tumors that have certain genetic features (HRD/FAD) or are growing despite immunotherapy. The experimental drug CP-506 is designed to activate only in low-oxygen areas of tumors, potentially killing cancer cells while sparing healthy tissue. The trial will test CP-506 alone, with chemotherapy (carboplatin), or with immunotherapy, to find the safest dose and see if it helps control the disease. About 126 participants will be enrolled.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Academisch Ziekenhuis Maastricht (Leading Centre)
RECRUITINGMaastricht, Limburg, 6229HX, Netherlands
Contact
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Erasmus MC
RECRUITINGRotterdam, Netherlands
Contact
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Institut Jules Bordet
NOT_YET_RECRUITINGBrussels, Belgium
Contact
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Institut Vall d'Hebron
NOT_YET_RECRUITINGBarcelona, 08035, Spain
Contact Phone: •••-•••-••••
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UZ Gent
NOT_YET_RECRUITINGGhent, 9000, Belgium
Contact Phone: •••-•••-••••