Can corneal transplant patients ditch steroids after one year?

NCT ID NCT05716945

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 22 times

Summary

This study tests a gentler steroid eye drop plan after corneal transplant surgery to see if it prevents rejection with fewer side effects. About 342 adults getting a DMEK transplant will be randomly assigned to different steroid schedules. The goal is to find a cost-effective way to protect the new cornea while reducing eye pressure problems and possibly allowing patients to stop steroids after one year.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Amsterdam Universitair Medisch Centrum

    RECRUITING

    Amsterdam, North Holland, 1105 AZ, Netherlands

  • Deventer Ziekenhuis

    RECRUITING

    Deventer, Overijssel, 7400 GC, Netherlands

  • Gelre Ziekenhuizen

    RECRUITING

    Apeldoorn, Gelderland, 7300 DS, Netherlands

  • Leiden Universitair Medisch Centrum

    RECRUITING

    Leiden, South Holland, 2333 ZA, Netherlands

  • Maastricht Universitair Medisch Centrum+

    RECRUITING

    Maastricht, Limburg, 6202 AZ, Netherlands

  • Radboud Universitair Medisch Centrum

    RECRUITING

    Nijmegen, Gelderland, 6500 HB, Netherlands

  • Universitair Medisch Centrum Groningen

    NOT_YET_RECRUITING

    Groningen, Provincie Groningen, 9700 RB, Netherlands

  • Universitair Medisch Centrum Utrecht

    NOT_YET_RECRUITING

    Utrecht, Utrecht, 3584 CX, Netherlands

Conditions

Explore the condition pages connected to this study.