Can corneal transplant patients ditch steroids after one year?
NCT ID NCT05716945
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new, gentler steroid eye drop plan after corneal transplant surgery. The goal is to prevent rejection while reducing side effects like high eye pressure. About 342 adults getting a DMEK transplant will be followed for two years to see if a milder steroid works as well and if patients can safely stop all drops after one year.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Amsterdam Universitair Medisch Centrum
RECRUITINGAmsterdam, North Holland, 1105 AZ, Netherlands
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Deventer Ziekenhuis
RECRUITINGDeventer, Overijssel, 7400 GC, Netherlands
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Gelre Ziekenhuizen
RECRUITINGApeldoorn, Gelderland, 7300 DS, Netherlands
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Leiden Universitair Medisch Centrum
RECRUITINGLeiden, South Holland, 2333 ZA, Netherlands
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Maastricht Universitair Medisch Centrum+
RECRUITINGMaastricht, Limburg, 6202 AZ, Netherlands
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Radboud Universitair Medisch Centrum
RECRUITINGNijmegen, Gelderland, 6500 HB, Netherlands
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Universitair Medisch Centrum Groningen
NOT_YET_RECRUITINGGroningen, Provincie Groningen, 9700 RB, Netherlands
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Universitair Medisch Centrum Utrecht
NOT_YET_RECRUITINGUtrecht, Utrecht, 3584 CX, Netherlands
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New surgical twist may save sight in babies with rare glaucoma
- Built-In eye scanner could give surgeons a live 3D view during operations
- Could a glaucoma eye drop also heal the cornea?
- Which corneal transplant is best? 1,000-Patient study aims to find out
- Divers' eye pressure spikes during breath-holds, study finds