Can a gout drug help lung cancer treatment reach the brain?

NCT ID NCT07485452

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether adding febuxostat (a gout medicine) to the standard lung cancer drug osimertinib can increase the amount of osimertinib that reaches the brain. It involves 7 adults with a specific type of advanced lung cancer who are already taking osimertinib. Researchers will measure drug levels in spinal fluid before and after adding febuxostat to see if the combination works.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Maastricht UMC+

    RECRUITING

    Maastricht, Netherlands

  • The Netherlands Cancer Institute

    NOT_YET_RECRUITING

    Amsterdam, Netherlands

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