Liver function may change how this drug works – early study begins
NCT ID NCT07269301
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study by Pfizer looks at how different levels of liver function affect the processing of a new drug called PF-07328948. About 26 adults with and without liver impairment will take a single tablet and stay at the clinic for 6 days for monitoring and blood tests. The goal is to see if liver problems change how the drug moves through the body, which could guide future dosing.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
PF-07328948 (a drug taken as a tablet)
What this could lead to
If successful, this study could help determine safe dosing of PF-07328948 for people with liver problems.
What could go wrong
This is a very early Phase 1 trial with only 26 participants, so results may not apply broadly. The drug may still fail in later studies.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Genesis Clinical Research, LLC
RECRUITINGTampa, Florida, 33603, United States
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Orange County Research Center
RECRUITINGLake Forest, California, 92630, United States
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Orlando Clinical Research Center
RECRUITINGOrlando, Florida, 32809, United States