New Alzheimer's drug enters human safety trials

NCT ID NCT06657768

Recruiting now Disease control Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This early-stage study tests a new drug called LY4006895 in healthy volunteers and people with early symptomatic Alzheimer's disease. The main goal is to check if the drug is safe and how the body processes it. The study has two parts: a single dose in healthy people and multiple doses in Alzheimer's patients over several months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: LY4006895
What this could lead to: If this drug is safe and shows promise, it could lead to a new treatment option for early Alzheimer's disease.
What could go wrong: This is an early Phase 1 trial focused on safety, not effectiveness. The drug may not work or could have side effects. Results are years away from any potential treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Alzheimer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER DISEASE HEALTHY

Contacts and locations

Locations

Aqualane Clinical Research
NOT_YET_RECRUITING

Naples, Florida, 34105, United States
Atlanta Center of Medical Research
RECRUITING

Atlanta, Georgia, 30331, United States
CenExel iResearch, LLC (CenExel iRA)
RECRUITING

Decatur, Georgia, 30030, United States
CenExel-HRI
RECRUITING

Marlton, New Jersey, 08053, United States
Collaborative Neuroscience Network - CNS
RECRUITING

Los Alamitos, California, 90720, United States
Duke Early Phase Research Unit
NOT_YET_RECRUITING

Durham, North Carolina, 27710, United States
K2 Medical Research
RECRUITING

Maitland, Florida, 32751, United States
K2 Medical Research - Tampa
NOT_YET_RECRUITING

Tampa, Florida, 33634, United States
K2 Medical Research - The Villages
RECRUITING

Lady Lake, Florida, 32159, United States
National Center for Geriatrics and Gerontology
NOT_YET_RECRUITING

Ōbu, 4748511, Japan
Progressive Medical Research
NOT_YET_RECRUITING

Port Orange, Florida, 32127, United States
QUEST Research Institute
NOT_YET_RECRUITING

Farmington Hills, Michigan, 48334, United States
The University of Tokyo Hospital
NOT_YET_RECRUITING

Bunkyō City, 113-8654, Japan

More trials for these conditions

Other studies related to the condition(s) this trial covers.