Cure My Disease

Don't miss your cure!

 Log in / Sign up

Scientists probe brain networks in depression with High-Tech tools

NCT ID NCT05977439

Recruiting now Knowledge-focused Sponsor: Medical University of South Carolina Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 22, 2026 · Updated 3 times

Summary

This research study examines how brain activity changes during emotional and thinking tasks in people with depression and healthy volunteers. Using brain scans (EEG, fMRI) and mild brain stimulation (TMS), researchers aim to understand the brain circuits involved in mood and suicidal thoughts. The study includes 120 participants and may also involve brief cognitive behavioral therapy (CBT) to see how it affects brain function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Transcranial magnetic stimulation (TMS) and cognitive behavioral therapy (CBT)
What this could lead to
If successful, this research could point toward better ways to treat depression and suicidal thoughts by understanding how brain activity relates to emotions and thinking.
What could go wrong
This is an early-stage study focused on understanding brain function, not testing a proven treatment. The results may not lead to immediate therapies, and individual responses may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DEPRESSION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Depression depressive disorder major depressive disorder Suicidal Ideation Suicide Prevention

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION DEPRESSION - MAJOR DEPRESSIVE DISORDER HEALTHY MAJOR DEPRESSIVE DISORDER SUICIDAL IDEATION

Contacts and locations

Locations

  • Medical Univeristy of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.