SUICIDAL IDEATION

This study aims to reduce suicidal thoughts and behaviors in 100 adults with PTSD by combining two proven treatments: prolonged exposure therapy and a crisis response plan. Participants will receive either the combined therapy or prolonged exposure with standard care. The goal is…

This study aims to reduce suicide among sexual and gender diverse young adults aged 18-24. It compares two brief suicide prevention programs adapted for this group, delivered via telehealth in primary care clinics. About 1,485 participants who screen positive for suicide risk but…

This study tests a short therapy program (ASSIP-OA) designed to prevent suicide in adults aged 65 and older. Researchers will compare the program to usual care in 132 participants, tracking suicide attempts and deaths over two years. The goal is to see if this brief intervention …

This study tests a program called TAILOR that helps teenagers with insomnia improve their sleep. The goal is to see if better sleep can lower their risk of suicidal thoughts and actions. The study will include 235 teens aged 11 to 18 who have had recent suicidal thoughts and slee…

This study tests an online training program for school counselors to help them prevent suicide among teenagers. The program teaches counselors how to spot warning signs, talk to at-risk students, and manage crises. Researchers will measure whether the training improves counselors…

This study compares a new, lower-energy seizure therapy (LAP-ST) to standard electroconvulsive therapy (ECT) for quickly reducing suicidal thoughts in people with depression, bipolar disorder, or schizoaffective disorder. About 30 adults will receive one of the two treatments. Th…

This study tests whether an online recovery education and support program, led by trained teen peers and support specialists, can help teens aged 15-18 who have been recently discharged from a psychiatric facility. The program includes one-on-one and small group meetings over 8 w…

This study tests a fast-acting, non-invasive treatment called transcranial magnetic stimulation (TMS) for teens and young adults aged 15-25 with depression and suicidal thoughts. Over 5 days, participants receive brain stimulation guided by MRI, with no surgery or medication invo…

This study tests a smartphone-based sleep program (Sleepio) for teens ages 14-18 who have trouble sleeping and were recently hospitalized for suicidal thoughts or behaviors. The goal is to see if improving sleep can reduce suicidal thinking. Participants will either get the sleep…

This study tests two mindfulness-based programs designed for Korean adolescents and young adults who struggle with suicidal thoughts or self-harm. About 100 participants aged 15 to 30 will either join the program or receive usual care. The goal is to see if the program reduces su…

This study tests a new type of talk therapy that focuses on shame, a key emotion linked to suicidal thoughts and actions. About 42 teens aged 13-18 who are in the hospital for suicide risk will get either this shame-focused therapy or standard support. The goal is to see if the t…

This study tests a non-invasive brain stimulation technique called accelerated theta burst stimulation (aTBS) to see if it can reduce suicidal thoughts in people with treatment-resistant depression. Researchers will compare two types of stimulation (bilateral vs. unilateral) in 7…

This study will test a 20-week therapy called Dialectical Behavior Therapy for Adolescents (DBT-A) in 140 teens aged 13-18 who have self-harmed or had suicidal thoughts in the past six months. Researchers want to see if it reduces self-harm, suicide attempts, and depression, and …

This study tests whether deep transcranial magnetic stimulation (dTMS) is safe and helpful for teens aged 14-18 who are in the hospital for major depression. Sixty participants will receive either real or sham dTMS alongside their usual care. The goal is to see if dTMS can ease d…

This study tests a mobile program called WellPATH-PREVENT for adults aged 50 to 90 who were recently hospitalized for suicidal thoughts or a suicide attempt. The goal is to see if the app helps them better manage their emotions and lowers their risk of future suicidal thoughts. P…

This study tests a digital program called I-CARE for teens aged 12-17 who are waiting in the emergency room after a suicide attempt or mental health crisis. The program teaches coping skills through a tablet or phone, guided by a non-clinical helper. Researchers want to see if it…

This study tests if a single low dose of ketamine, given in the emergency department, is safe and practical for adults with severe suicidal thoughts. Researchers will monitor side effects and ask staff about their experience. The goal is to see if ketamine can quickly ease suicid…

This study tests a program called SUPERCEDE that helps veterans at risk for suicide get faster access to mental health services. It combines counseling, crisis planning, and care coordination between VA and community doctors. About 100 veterans will be randomly assigned to SUPERC…

This study tests an app designed to help teens and young adults with suicidal thoughts stay safe. The app includes a personalized safety plan made with their doctor, plus videos to teach coping skills and improve communication with parents. Researchers will compare usual care to …

This study tests a smartphone app called Jaspr Health for people who come to the emergency department with suicidal thoughts or recent suicide attempts. The app provides evidence-based tools and support during the wait time. Researchers will track 670 participants for 12 months t…

This early-phase study tests whether a non-invasive magnetic pulse treatment (iTBS) can safely reduce impulsivity and suicidal thoughts in veterans with mild traumatic brain injury. About 55 veterans will receive the treatment over two weeks. The goal is to gather initial safety …

This study tests whether morning light exposure can help regulate mood, improve sleep, and reduce suicidal thoughts in military personnel. Researchers will enroll 480 service members with mild depression or more. Participants will use a light device each morning to see if it impr…

This study tests whether adding a brief crisis coping strategy (Crisis Response Planning) to a standard PTSD talk therapy (Cognitive Processing Therapy) can reduce suicidal thoughts and behaviors in veterans and active-duty service members. About 190 participants with PTSD and re…

This study tests a new short-term treatment called Suicidal Crisis Intervention (SCI) for adults who have attempted suicide or are in a suicidal crisis. The goal is to reduce suicidal thoughts and related feelings like hopelessness. About 390 participants and their close ones wil…

This study compares two proven therapies—Dynamic Deconstructive Psychotherapy (DDP) and Brief Intervention and Contact (BIC)—to see which better reduces suicidal thoughts in teens and young adults aged 14 to 40. About 106 participants will receive one of the treatments for 6 mont…

This study tests whether a type of talk therapy, delivered over video calls, can reduce suicidal thoughts and attempts in adults with physical disabilities (like vision, hearing, or mobility problems). Researchers will enroll 60 people who have had recent suicidal thoughts or a r…

This study tests a 40-minute web-based program designed to teach Veterans coping skills for the emotional distress that comes with suicidal thoughts. About 180 Veterans who have had recent suicidal thoughts will be randomly assigned to either the web program or standard care. Res…

This study tests a program called Project RISE that helps college students become more aware of their body sensations and emotions. The goal is to see if this can reduce suicidal thoughts and eating disorder symptoms. Two hundred students with past or current suicidal thoughts or…

This study looks at how the brain works in people who have attempted suicide, those who have only thought about it, and two control groups. Researchers will use computer tasks to measure attention, impulse control, and other thinking skills. The goal is to find patterns that migh…

This study looks at how to best help teenagers (ages 11-17) who have been hospitalized for suicidal thoughts or actions. Researchers will compare different support strategies to see which ones work best to prevent future suicide attempts and reduce suicidal thinking. The goal is …

This study is testing a program called WeCare to help Black teenagers who are at risk for suicide. The program includes a quick screening in the emergency room, a brief safety planning session, and supportive text messages for six weeks afterward. Researchers want to see if this …

This study aims to improve suicide prevention in prisons by adapting three proven tools for the detention setting. Researchers will interview 20 prison staff and 20 detainees to gather feedback on how to make these tools more practical and effective. The goal is to reduce the hig…

This study is testing a smartphone app designed to help young adults aged 16 to 30 who are having suicidal thoughts. Participants will use the app for two months and complete surveys to see if the tool is easy to use and helpful for managing their risk. The goal is to learn wheth…

This study enrolls teens aged 12–17 who have had recent suicidal thoughts. They will learn a brief program about using social media in active, positive ways. Researchers will measure changes in feelings of loneliness, burdensomeness, and distress. The goal is to see if this appro…

This study looks at whether being awake during the late-night hours (2:00-4:00 AM) makes people feel more hopeless, have worse decision-making, and experience more suicidal thoughts. Adults who have had suicidal thoughts in the past six months will be tested in a lab and at home …

This study tests a digital program called Flourish designed to help teens aged 12-17 who have been cyberbullied and are at risk for suicide. About 80 teens will either use Flourish plus answer questionnaires or just answer questionnaires alone. Researchers want to see if the prog…

This study tests a digital program called Flourish designed to help teens who are cyberbullied and having suicidal thoughts. Researchers will work with 20 middle and high school students to see if the program is easy to use in schools and if it reduces distress and suicidal thoug…

This study aims to create a treatment prognosis calculator for 1,200 active-duty military members with suicidal thoughts. The goal is to predict who will improve with standard care and who needs a specialized therapy called Brief Cognitive Behavioral Therapy (BCBT). Participants …

This study follows 200 teens aged 12-18 who use cannabis daily or near-daily and have mild to severe depression. Using smartphone surveys several times a day, researchers will track how recent cannabis use and withdrawal affect mood, suicidal thoughts, and urges. The goal is to u…

This study is developing and testing a small-group program called THRiVE for veterans who left the military within the last year. The program is led by peers and focuses on improving mental health and reducing suicide risk. Up to 40 veterans will take part in the program and comp…

This study looks at how childhood trauma and stress might change tiny genetic molecules called microRNAs in the blood. Researchers will compare 450 adults with depression or suicidal thoughts to healthy volunteers. The goal is to better understand the biological links between ear…

This study looks at how a 9-week talk therapy called Engage & Connect changes brain activity in older adults (ages 50-80) who have depression and suicidal thoughts. Researchers will use brain scans to see if the therapy boosts activity in brain areas linked to feeling rewarded by…

This study tests whether using a life history calendar—a simple grid that helps people recall important life events—can improve how accurately adults in Hong Kong remember and report past mental health problems. Researchers will compare the standard interview method with the cale…

This study looks at how U.S. military members use emotion regulation strategies to reduce suicidal thoughts. Researchers will track participants' strategies and moods in real time using smartphone surveys. The goal is to understand which strategies work best and for whom, to impr…

This study aims to understand why medical students develop depression and other mental health problems. Researchers will follow up to 10,000 students for up to 12 years each, comparing those who enter medical school with those who do not. Participants fill out yearly online quest…