Could a single ketamine shot curb suicidal urges in the ER?
NCT ID NCT06085937
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial tests whether a single low-dose injection of ketamine is safe and practical for adults who come to the emergency department with severe suicidal thoughts. Researchers will monitor side effects and ask staff about their experience. If successful, it could offer a quick way to ease suicidal thinking while patients wait for psychiatric help.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ketamine
What this could lead to
If it works, this could provide a fast-acting option to reduce suicidal thoughts in the emergency room, buying time for further psychiatric care.
What could go wrong
This is a very early Phase 1 trial with only 50 participants, so it may not prove effective or safe for broader use. Ketamine can cause side effects like dissociation or blood pressure changes.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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University of Kansas Medical Center Emergency Department
RECRUITINGKansas City, Kansas, 66160, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Kansas Strawberry Hill Campus
NOT_YET_RECRUITINGKansas City, Kansas, 66101, United States
Contact Email: •••••@•••••