SUICIDE

This study tests a 6-month remote support program called Pathfinding for active-duty soldiers recently discharged from psychiatric hospital care. The goal is to see if Pathfinding, added to standard care, reduces suicidal behavior compared to standard care alone. About 1,500 sold…

This study tests a gamified mobile health app designed to reduce suicide risk in adults with mental disorders after they leave the hospital. The app uses game-like features to encourage treatment adherence and follow-up visits. Researchers will enroll 640 participants in Shenzhen…

This study tests a counseling program called Friendship Bench + Safety Planning for teens aged 13-19 living with HIV who have had suicidal thoughts. The goal is to see if the program is practical, acceptable, and helps reduce suicidal thoughts and improve HIV care. Sixty particip…

This study tests whether adding intravenous ketamine to internet-based cognitive behavioural therapy (i-CBT) can quickly reduce suicidal thoughts and behaviors in people with treatment-resistant depression. About 110 adults will receive weekly i-CBT for 13 weeks, and half will al…

This study looks at two different talk therapies for Veterans recently hospitalized for suicide risk. 136 Veterans will be randomly assigned to one of the therapies and followed for a year. Researchers will also use brain scans to see if they can predict who might attempt suicide…

This study tests whether a short problem-solving therapy can help prevent suicide in adults aged 50 and older who are having suicidal thoughts. About 212 participants will be randomly assigned to receive the therapy face-to-face, by phone, via a smartphone app, or to continue wit…

This study aims to reduce suicide among sexual and gender diverse young adults aged 18-24. It compares two brief suicide prevention programs adapted for this group, delivered via telehealth in primary care clinics. About 1,485 participants who screen positive for suicide risk but…

This study tests a short therapy program (ASSIP-OA) designed to prevent suicide in adults aged 65 and older. Researchers will compare the program to usual care in 132 participants, tracking suicide attempts and deaths over two years. The goal is to see if this brief intervention …

This study is testing a 90-day support program called 'Caring Connections' designed to prevent suicide in high-risk teenagers. The program connects teens with mental health services, helps create safety plans, and builds a network of community support, often through faith-based o…

This study tests a 90-day program called Caring Connections that helps high-risk youth ages 13-19 who have suicidal thoughts or behaviors. The program provides support, safety planning, and connections to services. Researchers will compare this program to usual care to see if it …

This study is testing two self-guided online therapy courses for veterans who have depression or have had suicidal thoughts. About 472 veterans from several states will use one of the programs on their own computer or tablet. The goal is to see if these online tools are helpful a…

This study tests a new drug called (2R,6R)-HNK to see if it can quickly improve symptoms in people with major depression that hasn't responded to other treatments. About 50 adults aged 18 to 70 will receive four infusions of HNK and four of a placebo over several weeks, with thei…

This study compares two proven emergency care methods for teens and young adults (ages 13-24) who come to the ER with suicidal thoughts or actions. The goal is to see which approach better prevents suicide attempts and helps them start mental health treatment. Researchers will fo…

This study tests a mobile app called MIST designed to help veterans reduce suicidal thoughts. The app uses techniques to change unhelpful thinking patterns linked to suicide. Researchers will enroll 50 veterans to see if the app is easy to use and acceptable as an extra support a…

This study tests a new, one-session therapy called Brief Skills for Safer Living to see if it can reduce suicidal thoughts in adults. 150 people across Canada will take part, with half receiving the therapy right away and the other half after a 3-month wait. The study measures ch…

This study tests if a single low dose of ketamine, given in the emergency department, is safe and practical for adults with severe suicidal thoughts. Researchers will monitor side effects and ask staff about their experience. The goal is to see if ketamine can quickly ease suicid…

This study tests a new short-term treatment called Suicidal Crisis Intervention (SCI) for adults who have attempted suicide or are in a suicidal crisis. The goal is to reduce suicidal thoughts and related feelings like hopelessness. About 390 participants and their close ones wil…

This study tests whether a type of talk therapy, delivered over video calls, can reduce suicidal thoughts and attempts in adults with physical disabilities (like vision, hearing, or mobility problems). Researchers will enroll 60 people who have had recent suicidal thoughts or a r…

This study tests a new follow-up program for 100 adults who have had a suicidal crisis and are staying at a crisis stabilization center. The program includes group sessions and phone check-ins to help people feel less alone and more supported. The goal is to see if this approach …

This study tests a 12-week therapy program that combines coping skills with trauma-focused care to help adults who had traumatic childhoods and are currently thinking about suicide. The goal is to see if this approach reduces suicidal thoughts and is practical and acceptable for …

This study is testing a virtual reality (VR) program for teens ages 13-18 who are in the hospital for suicidal thoughts or behaviors. The VR program lets them practice school and social situations in a safe, guided environment. The goal is to see if the program is easy to use and…

This study is testing a new program to help prevent suicide among LGBTQ+ youth and young adults aged 15 to 29. Participants will be randomly assigned to the program or a comparison group, and researchers will track suicide attempts and suicidal thoughts over a year. The goal is t…

This study tests whether a smartphone app featuring recovery stories from other teens can help reduce suicidal thoughts in at-risk adolescents. About 46 teens from The Bronx who have had recent suicidal thoughts and depression will use the app for a short time. The goal is to see…

This study looks at how to help Suicide Intervention Officers (SIOs) in the Connecticut Army National Guard. SIOs teach suicide prevention, watch for soldiers in crisis, and connect them to help. Researchers want to see if giving SIOs more support lowers suicide risk in their uni…

This study compares two short, proven crisis interventions for suicidal youth ages 12-24 in emergency rooms across five U.S. cities. One method helps youth create a safety plan and get follow-up calls; the other teaches skills to handle relationship problems that can lead to cris…

This study is testing a digital platform that uses smartphone data (like sleep and activity patterns) to help therapists better support teens at high risk for suicide. About 78 teens aged 13-18 who are already in an intensive therapy program will use the platform alongside their …

This study tests a mobile health app designed to reduce stigma about suicide and improve knowledge about how to get help. About 214 adults in Spain will use the app and answer daily questions. The goal is to see if the app makes people more willing to seek support and less judgme…

This study is testing a program that helps school health clinics in rural West Virginia regularly screen teenagers for suicide risk. Researchers will work with providers, parents, and teens to adapt the program to fit local needs. About 30 youth will take part to see if the scree…

This study is testing a program that combines therapy (CBT) with a team of caring adults chosen by the teen to help prevent suicide. Researchers want to see if Black teens aged 12-17 who are at risk for suicide find this program acceptable and practical. The study will enroll 15 …

This study aims to improve suicide prevention in prisons by adapting three proven tools for the detention setting. Researchers will interview 20 prison staff and 20 detainees to gather feedback on how to make these tools more practical and effective. The goal is to reduce the hig…

This study explores whether offering follow-up calls to people who contact the Flemish suicide helpline (Zelfmoordlijn 1813) helps them feel supported and connected to care. Researchers will interview callers and helpline staff to see if this callback approach is practical and he…

This study tests whether sending supportive text messages to parents can help teens who recently visited the emergency room for suicidal thoughts or attempts. Researchers will track teen suicidal behavior and parent stress over six weeks. The study involves 420 parent-teen pairs …

This study is creating and testing a new group therapy for veterans who have recently had a suicidal episode. The therapy, called Continuous Identity-Cognitive Therapy (CI-CT), focuses on helping veterans rebuild hope, self-identity, and relationships. About 57 veterans will help…

This study aims to learn more about how depression, bipolar disorder, and suicide risk affect people and how treatments work. Researchers will follow 500 adults already receiving care at the NIH, using interviews, questionnaires, and optional tests like blood draws and brain scan…

This study looks at how teenagers who have hurt themselves learn and use coping skills in daily life. About 200 teens and a parent will practice two skills during discussions while their body responses are measured. Some will also get brain scans. The goal is to see what helps th…

This study tests whether brief smartphone messages can help adults hospitalized for suicidal thoughts use their safety plan and lower their risk. Participants answer surveys up to 4 times daily and may receive a tailored intervention based on their current urges. The goal is to s…

This study looks at whether trained peer support specialists can help LGBTQ+ youth (ages 12-17) who are involved with juvenile justice, child welfare, or mental health services and have thoughts of suicide or self-harm. The goal is to see if this approach is practical and accepta…

This study is testing whether a set of suicide prevention strategies can work in rural Nepal's primary care clinics. About 147 healthcare workers and patients will take part to see if the program is practical and well-received. The goal is to gather information to design a larger…

This study looks at how the daily rhythm of sleep and social activity relates to mood and suicidal thoughts in older adults who recently lost a spouse or life partner. Researchers will track 169 participants over 12 months using surveys and activity monitors. The goal is to under…

This study looks at 300 people with mood disorders to find out what makes someone more likely to think about or attempt suicide. Researchers will use questionnaires and collect blood and urine samples to look for biological and psychological clues. The goal is to create a list of…