SUICIDE

This trial tests whether a safety planning intervention plus follow-up phone calls, delivered either by emergency department staff or via a telehealth referral center, can reduce suicide attempts and deaths in adults who come to the ER with suicidal thoughts or behaviors. Over 2,…

This study tests a short therapy called ACT for Life for veterans hospitalized due to suicide risk. The therapy includes 3 to 6 sessions in the hospital and up to 4 follow-up sessions to help veterans build a life worth living and reduce suicide attempts. Researchers will compare…

This study tests a program called S.A.F.E. Firearm in up to 15 Illinois health centers. Pediatric clinicians will talk with parents about storing guns securely and offer a free cable lock during well-child visits. Researchers want to see if training and support help clinics adopt…

This study tests whether training teachers in culturally responsive practices can reduce violence and suicide risk among African American youth. Over 1,600 students and teachers from multiple schools will participate. The program includes workshops for teachers on reducing bias a…

This study tests a program called Wingman-Connect, designed to reduce suicide risk among U.S. Air Force personnel in training. Nearly 3,000 recruits will be randomly assigned to either the Wingman-Connect training or a standard control session. The program teaches skills like bui…

This study tests a new program designed to prevent suicide among LGBTQ+ youth and young adults aged 15 to 29. Researchers will compare the program to usual care in 170 participants from Southern California who have recent suicidal thoughts. The goal is to see if the program reduc…

This study compares two suicide prevention programs designed specifically for autistic youth aged 12-24. One program is a safety planning intervention (SPI-A), and the other adds follow-up contacts (SPI-A+). Researchers will track changes in suicidal thoughts and behaviors over a…

This study tests a web-based tool called Lock and Protect that helps caregivers of teens at risk for suicide find safe ways to store medications, firearms, and other dangerous items at home. The tool guides parents through options and creates a safety plan. The trial will enroll …

This trial tests a 6-week therapy program for youth (ages 12-17) who come to the emergency department with suicidal thoughts or behaviors. The program involves weekly sessions with a therapist for the teen and their family. Researchers want to see if this focused approach reduces…

This study looks at whether long (over 5 days) or compulsory psychiatric hospital stays affect self-harm and suicide in people with borderline personality disorder. Researchers will compare clinics across Sweden that use these practices more or less often, tracking outcomes like …

This study is testing a new program called mSTARS for people who drink heavily and have been hospitalized for a suicide crisis. The program combines in-hospital therapy with a smartphone app to help manage emotions after leaving. Ten participants will try the program and give fee…

This study gives ketamine to 120 people with major depression and suicidal thoughts who are not on other psychiatric medications. Researchers use brain scans and a gentle nose swab to see how ketamine changes brain connections and neuron activity. The goal is to understand why ke…

This study is creating a large registry of 5,000 young people aged 8 to 20 who have depression or suicidal thoughts. Researchers will collect data from clinics across Texas to better understand these conditions and develop models to predict outcomes. The goal is to improve popula…

This study adapts a program called Youth-Nominated Support Team (YST) for suicidal adolescents who are at high risk for psychosis. The goal is to see if having a personally chosen support team helps these teens feel more connected, hopeful, and engaged in treatment. About 70 part…

This study is testing an online learning module called SAFETY-Parent, designed to help parents support youth who are thinking about or have attempted suicide. About 65 parents and youth will try the module and give feedback on how easy it is to use and how helpful it feels. The g…

This study aims to understand how the brain's pain-processing systems relate to a person's ability to attempt suicide. Researchers will use fMRI scans to measure brain activity in 90 adults with depression while they experience pressure pain. The goal is to identify neural patter…

This study tests a program where trained peer coaches help people with financial hardship and suicide risk learn money management skills, create a financial plan, and connect with community resources. The program includes group and one-on-one video sessions over several months. T…

This study looks at how a nasal spray called esketamine can quickly reduce suicidal thoughts in people with severe depression. Researchers want to find out if symptoms like loss of pleasure (anhedonia) or emotional pain can predict who will benefit most. The study re-analyzes dat…

This study aimed to see if a fast-acting form of brain stimulation (called accelerated TMS) could change brain activity linked to suicidal thinking in adults hospitalized for major depression. The researchers planned to measure changes in suicidal thoughts using a standard questi…