Nasal spray shows promise against suicidal thoughts – but who benefits most?
NCT ID NCT07199179
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how a nasal spray called esketamine can quickly reduce suicidal thoughts in people with severe depression. Researchers want to find out if symptoms like loss of pleasure (anhedonia) or emotional pain can predict who will benefit most. The study re-analyzes data from two earlier trials involving 456 patients. It does not test a new treatment but aims to better understand how esketamine works.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Locations
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Chu Montpellier
Montpellier, France