Brain zaps tuned to your wiring: a new hope for depression?

NCT ID NCT07753473

First seen Aug 07, 2026 ยท Last updated Aug 07, 2026

Summary

This study investigates whether transcranial magnetic stimulation (TMS), a non-invasive technique that uses magnetic pulses to stimulate brain areas, can influence the coupling between heart and brain activity in individuals with depressive tendencies. Participants will undergo brain scans and receive different types of TMS targeting personalized brain regions, while their brain and heart signals are recorded. The goal is to understand how targeted stimulation affects this heart-brain connection, which could inform future personalized treatments for depression.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Transcranial magnetic stimulation (TMS) targeting personalized brain regions
What this could lead to
If successful, this could pave the way for more personalized, non-invasive brain stimulation treatments for depression, potentially improving how the brain and heart communicate.
What could go wrong
This is an early-stage study with a small number of participants, so results may not apply broadly. TMS is generally safe but can cause mild discomfort or headache.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Xidian University

    RECRUITING

    Xi'an, Shaanxi, 71000, China

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