University Hospital, Montpellier

This study tests whether adding regular motivational talks to standard care helps people with alcohol addiction stay sober longer after leaving the hospital. Researchers will compare two groups of 104 adults: one receiving motivational interviews every two weeks for four months, …

This study is testing a new synthetic bone graft material to see if it helps people heal better after spinal fusion surgery for severe, chronic back pain caused by worn-out spinal discs. It will compare the new material to a standard one in 100 adults, measuring how well the spin…

This study is testing if placing a small stent (a tiny mesh tube) in a narrowed vein in the brain can help reduce high pressure inside the skull for people with idiopathic intracranial hypertension (IIH). Participants, who have had IIH for over a year and still have symptoms like…

This study is testing whether a planned hospital stay for a full health check-up and personalized care plan can help lower the risk of heart attacks and strokes. It involves 70 adults who are at high risk for heart disease, either because they have multiple risk factors or have a…

This study is testing a new psychological therapy program for people with depression. It compares a specialized program focused on self-identity to a standard acceptance-based therapy. Researchers will measure how well symptoms improve and whether depression returns within 6 mont…

This study is testing a new treatment approach for rheumatoid arthritis. It compares two strategies: one group starts with a common arthritis drug for 12 weeks, then switches to a different drug for 36 weeks. The other group stays on the first drug the whole time. The goal is to …

This study is testing a new, less invasive way to perform a mastectomy for breast cancer. It uses a small camera and tools inserted through a single cut in the armpit to remove breast tissue, aiming to hide the scar and preserve the nipple. The goal is to see if this endoscopic t…

This study is testing a special education program designed to help adults whose epilepsy is not well controlled. The program teaches patients how to recognize and manage risks in their daily lives to stay safer. Researchers will compare this new program to the usual education to …

This study is testing whether specialized addiction support after a liver transplant helps patients stay away from alcohol. It will involve 720 people who received a transplant due to alcohol-related liver disease. Half will receive standard follow-up care, while the other half w…

This study is testing if a procedure to physically reopen a blocked neck artery, combined with standard medication, leads to better recovery after a stroke than medication alone. It will involve 200 adults who have had a recent stroke caused by this specific type of blockage. The…

This study is testing if placing a small stent (a tiny mesh tube) in a narrowed brain vein, along with standard medication and weight loss advice, works better than just the medication and advice alone for people newly diagnosed with idiopathic intracranial hypertension (IIH). II…

This study is testing if delivering chemotherapy directly into the liver artery is more effective for a rare bile duct cancer when initial treatment has stopped working. It aims to shrink tumors in patients whose cancer is confined to the liver and cannot be surgically removed. T…

This study is testing whether surgery for early-stage mouth and throat cancer can be safely performed as an outpatient procedure, allowing patients to go home the same day. It involves removing the main tumor and checking a key lymph node (sentinel node) for cancer spread using a…

This study is testing a new type of directional brain electrode (CARTESIA™) for people with Parkinson's disease who are already scheduled for deep brain stimulation (DBS) surgery. The goal is to see if this newer electrode can better control movement symptoms like tremors and sti…

This study is testing a targeted chemotherapy treatment for liver cancer in patients who also have liver scarring (cirrhosis) and cannot have surgery. Doctors inject a chemotherapy drug mixed with an oily agent directly into the liver's blood supply to try to control the tumor. T…

This study is testing which level of sodium in dialysis fluid works best for ICU patients with sudden kidney failure. Researchers are comparing a standard higher sodium level against a slightly lower one to see if the lower level can control dangerous fluid buildup just as well w…

This study is testing whether using a specific blood marker (called sST2) to guide treatment decisions helps people with acute heart failure. It aims to see if this approach reduces hospital readmissions, controls costs, and improves patients' quality of life over two years. Abou…

This study is testing if adding two immunotherapy drugs, atezolizumab and bevacizumab, to a standard heat treatment (radiofrequency ablation) can better prevent liver cancer from returning. It will involve 202 adults with early-stage liver cancer. The goal is to see if this combi…

This study aims to find genetic causes for disorders of sex development (DSD) when standard genetic tests haven't provided answers. Researchers will use a new mapping technique on blood samples from 20 participants with XY chromosomes and moderate to severe DSD. The goal is to id…

This study is testing whether a specialized nurse can effectively screen for brain development issues in young children (ages 1-5) who were born with heart defects. Many of these children are at high risk for these issues, but there aren't enough specialists to check everyone. Th…

This study is testing a new method to check a baby's chromosomes very early in pregnancy. Researchers want to see if they can get accurate genetic information from cells collected with a simple, non-invasive cervical swab as early as 7 weeks. The goal is to provide parents with i…

This study is testing a simple questionnaire designed to help measure how well a child's allergy symptoms are being controlled by their treatment. Researchers want to see if this tool works for children aged 5 to 11, as similar tests already exist for adults and teens. The goal i…

This study is testing a new diagnostic tool that combines a blood test with a short questionnaire to help doctors tell the difference between bipolar disorder and regular depression. It involves about 623 adults who are currently experiencing a depressive episode and are visiting…

This study is testing whether women having a planned C-section can safely skip having a bladder catheter placed during surgery. Researchers want to see if simply urinating right before the procedure works just as well for preventing urinary problems, while potentially reducing pa…

This study is testing if a new educational program about the science of pain helps people with long-term low back pain become and stay more physically active. Researchers will compare this new program to a traditional 'back school' approach. They will measure daily steps using a …

This study aims to understand how hand osteoarthritis starts and progresses. Researchers will follow 150 patients with early-stage hand arthritis, using imaging like MRI and ultrasound to look for signs that predict which joints will get worse. The goal is to identify patients at…

This study aims to find specific markers in the blood that can tell the difference between liver inflammation caused by cancer immunotherapy drugs and other types of autoimmune liver disease. Researchers will compare blood samples from 60 adults with these conditions. The goal is…

This study aims to measure how common certain food allergies are in people visiting an allergy clinic in France. Researchers will test 2000 patients for reactions to six foods (like peach, apple, and sesame) that contain proteins linked to severe allergies. The goal is to better …

This study aims to make medical lab tests more reliable and consistent. Researchers are testing new reference materials to ensure that blood tests for conditions like hormone levels and infections give the same accurate result, no matter which hospital or machine performs the tes…

This study aims to understand if sleep problems are connected to faster memory loss in people with early-stage Alzheimer's disease. Researchers will track 132 participants over time, measuring their sleep patterns and memory test scores. The goal is to see if treating sleep issue…

This study aims to understand if exposure to certain chemicals in the environment or parents' workplaces is connected to a common birth defect in boys called cryptorchidism, or undescended testicles. Researchers will compare the chemical exposures of parents whose children have t…

This study aims to understand if tiny particles in a premature baby's umbilical cord blood can serve as early warning signs for severe health problems. Researchers will collect cord blood from 30 infants born before 28 weeks and analyze these particles to see if they correlate wi…

This study aims to understand if newer, high-efficacy MS treatments are better at slowing brain shrinkage (atrophy) than older, medium-efficacy treatments. Researchers will follow 400 people with relapsing-remitting MS for three years, using brain scans and other tests to track t…

This study aims to understand how factors like where you live, your income, pollution, and stress affect menstrual health. Researchers will observe 320 healthy women in France for one menstrual cycle, collecting daily saliva samples, activity data from a smart ring, and informati…

This study aims to better understand keratoconus, an eye condition where the cornea thins and bulges. Researchers will observe 200 participants for two years to see how the disease progresses and identify factors like eye rubbing or allergies that might influence it. The study wi…

This study aims to understand if people with restless legs syndrome (Willis-Ekbom disease) have increased nervous system activity that might explain their higher risk of heart problems. Researchers will compare 40 patients with the condition to healthy volunteers by measuring hea…

This study aims to find the specific gene responsible for Cutis Tricolor, a rare skin condition that causes unusual light and dark patches. Researchers will analyze DNA from patients aged 4-60 and their parents to identify the genetic cause. The goal is to better understand this …

This study aims to understand Huntington's disease better by measuring specific proteins in spinal fluid and blood. Researchers will compare 90 people with Huntington's disease to 45 people without the disease, looking for biological markers that track with disease severity. The …

This study aims to understand how the mix of different air pollutants in classrooms affects the health of children, especially those with allergies like asthma or eczema. Researchers will place advanced sensors in schools to monitor air and dust quality in real-time, while also c…

This study aims to understand how genetic spinocerebellar ataxia (SCA) disorders affect vision and eye health. Researchers will examine 60 people with SCA1, SCA2, SCA3, or SCA27B, including those with and without symptoms, using comprehensive eye tests. The goal is to identify wh…

This study aims to find a blood test that can predict how well patients with a type of lymphoma will respond to CAR-T cell therapy. Researchers will look at a process called 'trogocytosis' in immune cells from 85 patients and some healthy volunteers. The goal is to identify early…

This study aims to see if a new way of measuring movement smoothness can help track progress in people with chronic low back pain. Researchers will use small sensors to measure how smoothly participants move their backs before and after a standard rehabilitation program. The goal…

This study aims to understand why chronic leg swelling differs between patients. Researchers will use MRI scans and genetic tests on 48 people with leg swelling from two different causes. The goal is to see if differences in tissue and genes explain why compression stockings work…

This study aims to understand if exposure to common chemicals during pregnancy is linked to hypospadias, a genital birth defect in boys. Researchers are comparing 200 mothers of boys with and without the condition, analyzing hair samples for pollutants and using questionnaires. T…

This study aims to understand how electrical stimulation affects brain networks during awake surgery for low-grade brain tumors. Researchers will measure brain signals in 12 patients before, during, and after their tumor removal surgery. The goal is to learn how electrical impuls…

This study aims to better understand the potential early-life origins of endometriosis, a painful condition affecting 1 in 10 women. Researchers will compare two small groups of women—one with confirmed endometriosis and one without—by measuring a specific physical distance and c…

This study aims to understand if a person's tendency to feel shame can help predict future suicide attempts in people with Borderline Personality Disorder (BPD). Researchers will follow 688 adults with BPD for five years, checking in annually with questionnaires and interviews. T…

This study aims to understand why a phone support program called VigilanS helps prevent suicide attempts. Researchers will compare 120 people who have recently attempted suicide, some of whom had another attempt while in the program and some who did not. They will measure partici…