New Two-Step strategy aims to improve rheumatoid arthritis remission
NCT ID NCT05428488
First seen Oct 31, 2025 · Last updated May 12, 2026 · Updated 24 times
Summary
This study tests a new treatment plan for people with rheumatoid arthritis (RA) who still have active disease despite standard medications. The plan starts with a fast-acting drug (TNF inhibitor) for 12 weeks, then switches to a longer-acting drug (abatacept) to try to achieve remission. The trial will compare this two-step approach to using only TNF inhibitors. About 220 adults with RA who are ACPA-positive and on methotrexate or leflunomide will take part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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APHP Bicêtre
NOT_YET_RECRUITINGParis, France
Contact Email: •••••@•••••
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APHP Cochin
RECRUITINGParis, France
Contact Email: •••••@•••••
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APHP La Pitié Salpetrière
RECRUITINGParis, France
Contact Email: •••••@•••••
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CH du Mans
RECRUITINGLe Mans, France
Contact Email: •••••@•••••
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CHD Vendée
RECRUITINGLa Roche-sur-Yon, France
Contact Email: •••••@•••••
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CHR Orléans Nouvel hôpital d'Orléans
RECRUITINGOrléans, France
Contact Email: •••••@•••••
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CHU Bordeaux groupe Pellegrin
RECRUITINGBordeaux, France
Contact Email: •••••@•••••
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CHU de Brest La Cavale Blanche
RECRUITINGBrest, France
Contact Email: •••••@•••••
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CHU de Nantes
RECRUITINGNantes, France
Contact Email: •••••@•••••
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CHU de Nice
RECRUITINGNice, France
Contact Email: •••••@•••••
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CHU de Nîmes Carémeau
NOT_YET_RECRUITINGNîmes, France
Contact Email: •••••@•••••
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CHU de Strasbourg Hautepierre
NOT_YET_RECRUITINGStrasbourg, France
Contact Email: •••••@•••••
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CHU de Tours - Hopital Trousseau
RECRUITINGTours, France
Contact Email: •••••@•••••
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Centre Hospitalier Universitaire de Montpellier
RECRUITINGMontpellier, France, 34295, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centre Hospitalier de Cahors
NOT_YET_RECRUITINGCahors, France
Contact Email: •••••@•••••
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Centre hospitalier Princesse Grace
RECRUITINGMonaco, Monaco
Contact Email: •••••@•••••
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Chu Purpan
NOT_YET_RECRUITINGToulouse, France
Contact Email: •••••@•••••
Conditions
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