New combo therapy aims to stop liver cancer from coming back after ablation

NCT ID NCT04727307

First seen Nov 01, 2025 · Last updated May 10, 2026 · Updated 26 times

Summary

This study tests whether adding immunotherapy (atezolizumab) and a targeted drug (bevacizumab) before and after standard heat ablation can prevent liver cancer from returning. About 202 adults with small, early-stage liver tumors will be randomly assigned to receive ablation alone or ablation plus the drug combo. The goal is to see if the combo improves how long patients stay cancer-free.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CH Perpignan

    RECRUITING

    Perpignan, France

    Contact

    Contact

  • CHRU de Nancy

    RECRUITING

    Nancy, France

    Contact

    Contact

  • CHU Amiens

    RECRUITING

    Amiens, France

    Contact

    Contact

  • CHU Dijon

    RECRUITING

    Dijon, France

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    Contact

  • CHU Nîmes

    RECRUITING

    Nîmes, France

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    Contact

  • CHU d'Angers

    RECRUITING

    Angers, France

    Contact

    Contact

  • CHU de Grenoble

    RECRUITING

    Grenoble, France

    Contact

    Contact

  • CHU de Lille

    NOT_YET_RECRUITING

    Lille, France

    Contact

    Contact

  • CHU de Montpellier

    RECRUITING

    Montpellier, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Nantes

    RECRUITING

    Nantes, France

    Contact

    Contact

  • CHU de Nice

    NOT_YET_RECRUITING

    Nice, France

    Contact

    Contact

  • CHU de Poitiers

    RECRUITING

    Poitiers, France

    Contact

    Contact

  • CHU de Rennes

    RECRUITING

    Rennes, France

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  • Centre Georges François Leclerc

    RECRUITING

    Dijon, France

    Contact

    Contact

  • Hôpital Beaujon

    RECRUITING

    Clichy, France

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    Contact

  • Hôpital Cochin

    RECRUITING

    Paris, France

    Contact

    Contact

  • Hôpital Jean Verdier

    RECRUITING

    Bondy, France

    Contact

    Contact

  • Hôpital Saint Joseph

    RECRUITING

    Marseille, France

    Contact

    Contact

  • Institut Gustave Roussy

    RECRUITING

    Villejuif, France

    Contact

    Contact

Conditions

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