Brain vein stent could ease pressure and save sight in IIH patients

NCT ID NCT06919744

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether placing a small stent in a narrowed brain vein can reduce high pressure inside the skull and improve symptoms like vision loss, headache, and tinnitus. About 114 adults with newly diagnosed idiopathic intracranial hypertension will be randomly assigned to either standard care (medication and weight loss) or standard care plus the stenting procedure. Researchers will check if the stent helps resolve swelling of the optic nerve and normalize pressure within three months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

venous sinus stenting (a device procedure) plus acetazolamide and weight loss

What this could lead to

If it works, this could offer a new treatment option to reduce brain pressure and prevent vision loss in people with idiopathic intracranial hypertension.

What could go wrong

This is a relatively small, early-phase study (114 people) and stenting is an invasive procedure with risks like bleeding or infection. It may not prove better than standard care alone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

headache disorder intracranial hypertension pseudotumor cerebri Tinnitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Montpellier Hôpital Gui de Chauliac

    RECRUITING

    Montpellier, 34295, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de REIMS

    NOT_YET_RECRUITING

    Reims, 51092, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Toulouse

    NOT_YET_RECRUITING

    Toulouse, 31000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••