University Hospital, Montpellier

This study aims to find out if people with stable relapsing-remitting multiple sclerosis (MS) who are over 40 years old can safely switch from a strong, long-term medication (anti-CD20 therapy) to a milder one. Researchers want to see if switching reduces side effects and infecti…

This study is testing whether a short family-focused therapy can reduce early symptoms of post-traumatic stress in children and teens. It will involve 140 participants, aged 7 to 17, who experienced a traumatic event within the last three months. Researchers will compare the new …

This study aims to find the best surgical method for fixing simple breaks in the long bones of the hand. Researchers will compare three techniques—a screw inside the bone, a plate on the bone, or temporary pins—in 111 adults. They will track which method leads to better hand move…

This study compares two types of dental glue used to attach braces brackets, to see which one better prevents white spot lesions (early tooth decay). It involves 34 teens aged 10-16 who are getting braces. Each teen will have one side of their mouth treated with a traditional 3-s…

This study aims to see if surgery to correct severe spinal curvature (scoliosis) in children and young adults with cerebral palsy can improve their nutrition, help them gain weight, and enhance their quality of life. Researchers will measure food intake, weight, body composition,…

This study aims to find a better way to treat severe liver inflammation that can occur as a side effect of powerful cancer immunotherapies. It will compare a standard steroid treatment against a different drug called ursodeoxycholic acid (UDCA), which may have fewer side effects.…

This study aims to find early warning signs of patellar tendinopathy, commonly known as Jumper's Knee, in athletes. Researchers will use special cameras to analyze how 60 male athletes move when they jump and land, comparing those with and without knee issues. The goal is to spot…

This study is testing whether a smartphone app called 'emma' can help prevent suicide attempts in people at very high risk. It will involve 632 adults in France who recently attempted suicide and are already in a care program. Researchers will compare outcomes for six months betw…

This study is testing if a special type of writing workshop can help people with borderline personality disorder (BPD) function better in their social and work lives. 140 participants will receive standard therapy, and half will also attend workshops where they learn to rewrite a…

This study is testing if a targeted numbing injection, called an Erector Spinae Plane Block (ESPB), can provide fast relief for sudden, severe low back pain. Researchers will compare the injection to a placebo (a shot with no medicine) in 300 adults who come to the emergency room…

This study aims to understand how a mother's environment, lifestyle, and diet during pregnancy affect the health of her twin babies. Researchers will follow 120 women with twin pregnancies and their 240 children for one year, collecting information on air pollution, diet, and oth…

This study aims to understand how progesterone hormone levels change after a standard fertility medication (hCG) triggers ovulation. Forty women preparing for frozen embryo transfer will have blood tests over six days to monitor their hormone patterns. Researchers want to learn i…

This study aims to understand how to make a new mental health program work better for children and teens. Researchers will ask doctors, therapists, and program users what helps them collaborate effectively when a young person needs psychological support. The goal is to improve th…

This study aims to find out which viruses cause fever in babies under 3 months old. Researchers will compare nose and stool samples from 130 feverish babies to samples from healthy babies. The goal is to help doctors better tell viral and bacterial infections apart, which could r…

This study aims to find the best way to collect stool samples for analyzing gut bacteria. Researchers will compare different collection methods used in research against the current standard. The goal is to improve the accuracy and reliability of gut microbiome testing in future s…

This study aims to understand how traumatic experiences might influence suicidal thoughts and behaviors in teenagers receiving psychiatric hospital care. Researchers will compare 120 adolescents hospitalized for suicide attempts with those hospitalized for other mental health rea…

This study aims to understand why some people at high risk for rheumatoid arthritis (RA) develop the full disease while others do not. Researchers will follow 150 adults, including those with early signs and family members, for two years. They will track many factors like diet, s…

This study aims to understand the biological differences in children with ADHD, particularly focusing on inflammation and nutrition. Researchers will compare 80 children with and without ADHD to see if their immune and nutritional profiles differ and if these factors affect their…

This study aims to see if cancer cells from aggressive, recurring brain tumors (meningiomas) can be found in a patient's blood or spinal fluid. Researchers will test samples from 15 adults whose tumors have come back after surgery. The goal is to learn if these 'liquid biopsies' …

This study aims to find out if an allergy to contrast dye (used in medical scans) goes away over time. It will follow 100 adults who have tested positive for this allergy twice. Researchers want to see if the allergy persists and identify factors that might make it last longer.

This study aims to understand if having low muscle mass and strength before hip replacement surgery affects how well and how quickly older adults regain their independence. Researchers will follow 20 people aged 75 and older who are scheduled for hip surgery, measuring their musc…

This study is testing a new idea: that Borderline Personality Disorder (BPD) might be similar to an addiction, but to relationships instead of a substance. Researchers will compare 194 adults with BPD, bipolar disorder, or no mental health condition. They will use questionnaires,…

This study aims to collect blood samples from 1,000 patients to see if a 'liquid biopsy' blood test can better predict which small colon growths are cancerous and which are not. The goal is to help doctors decide if a patient needs surgery or can be safely monitored, potentially …