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Blood test may slash ALS diagnosis time from months to days

NCT ID NCT07706270

Not yet recruiting Diagnosis Sponsor: University Hospital, Montpellier Source: ClinicalTrials.gov ↗

First seen Jul 15, 2026 · Last updated Jul 21, 2026 · Updated 3 times

Summary

This study investigates whether measuring a protein called neurofilament light chain (NfL) in the blood can help doctors diagnose amyotrophic lateral sclerosis (ALS) more quickly and accurately. ALS is often hard to distinguish from other neurological diseases, leading to delays of up to 14 months. Researchers will take an extra blood sample from 138 adults with suspected ALS and measure NfL levels using advanced techniques. The goal is to see if NfL levels can reliably tell ALS apart from similar conditions and predict how the disease will progress.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a blood test measuring neurofilament light chain (NfL) levels
What this could lead to
If successful, this blood test could speed up ALS diagnosis, reduce misdiagnosis, and help doctors start treatment earlier.
What could go wrong
This is a diagnostic study, not a treatment trial. The test may not be accurate enough to replace current methods, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

amyotrophic lateral sclerosis disease motor neuron disorder neurodegenerative disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AMYOTROPHIC LATERAL SCLEROSIS (ALS) MOTOR NEURON DISEASES NEURODEGENERATIVE DISORDERS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

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