Can extra progesterone boost IVF success? new trial investigates
NCT ID NCT07613528
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 trial tests whether giving daily progesterone injections for 6 weeks after a positive pregnancy test can improve live birth rates in women with low progesterone levels. The study includes 214 women aged 18-37 who became pregnant through IVF. Half will receive the extra progesterone shots, and half will receive placebo injections, with neither the patients nor doctors knowing who gets what.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Progesterone (injectable and vaginal)
What this could lead to
If successful, this could show that extending progesterone shots for 6 weeks after a positive pregnancy test increases the chance of a live birth in women with low progesterone levels.
What could go wrong
This is a relatively small trial (214 participants) and only includes women aged 18-37 with specific progesterone levels, so results may not apply to everyone. The extra injections may cause discomfort or side effects without improving outcomes.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHU de Montpellier
Montpellier, 34295, France
Contact Phone: •••-•••-•••• Email: •••••@•••••