New study tests tailored suicide prevention for autistic youth

NCT ID NCT05398250

ENROLLING_BY_INVITATION Symptom relief Sponsor: University of North Carolina, Chapel Hill Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two suicide prevention programs designed specifically for autistic youth aged 12-24. One program is a safety planning intervention (SPI-A), and the other adds follow-up contacts (SPI-A+). Researchers will track changes in suicidal thoughts and behaviors over a year to see which approach works better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Safety Planning Intervention tailored for Autistic individuals (SPI-A) with or without follow-up contacts
What this could lead to: If successful, this could provide effective, tailored suicide prevention strategies for autistic youth, a group at high risk.
What could go wrong: This is a large study but still early in testing these specific adaptations. Results may not apply to all autistic youth, and the interventions may not reduce suicide rates as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

autism spectrum disorder Self-Injurious Behavior Suicidal Ideation Suicide Suicide Prevention

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTISM SPECTRUM DISORDER SUICIDAL AND SELF-INJURIOUS BEHAVIOR SUICIDAL IDEATION SUICIDE

Contacts and locations

Locations

Children's Hospital of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States
Kennedy Krieger Institute

Baltimore, Maryland, 21113, United States
Nationwide Children's Hospital

Columbus, Ohio, 43205, United States
Seattle Children's Hospital

Seattle, Washington, 98105, United States
University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, 27510, United States

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