New therapy aims to break the link between childhood trauma and suicide

NCT ID NCT05613972

Recruiting now Symptom relief Sponsor: Unity Health Toronto Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests a 12-week therapy called Integrated Suicide and Trauma Therapy (ISTT) in 20 adults with a history of childhood trauma and current suicidal thoughts. The therapy combines coping skills training with trauma-focused treatment to address both suicide risk and the lasting effects of trauma. Researchers will measure changes in suicidal ideation and whether participants find the therapy acceptable and helpful.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Integrated Suicide and Trauma Therapy (ISTT) - a 12-week psychotherapy combining coping skills and trauma processing
What this could lead to: If successful, this therapy could offer a new, targeted way to lower suicide risk in people with a history of childhood trauma.
What could go wrong: This is a very small pilot study with only 20 participants, so results may not apply to everyone. The therapy is new and unproven, and it may not reduce suicidal thoughts more than existing treatments.

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Conditions

The condition(s) this trial relates to.

injury major depressive disorder Suicide

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSIVE DISORDER SUICIDE TRAUMA

Contacts and locations

Locations

St. Michael's Hospital
RECRUITING

Toronto, Ontario, M5B 1M8, Canada

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