Fast brain zaps show promise for suicidal teens in new trial

NCT ID NCT07025720

Recruiting now Symptom relief Sponsor: University of California, Davis Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a non-invasive brain stimulation treatment called TMS for teens and young adults (ages 15-25) with depression and suicidal thoughts. Over 5 days, participants receive 10 sessions of magnetic pulses per day, guided by MRI scans. Researchers want to see if this fast treatment is practical and can reduce depression, suicidal thinking, and hospital visits. All 25 participants get the treatment, with follow-ups at 1 and 4 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcranial magnetic stimulation (TMS)
What this could lead to: If it works, this could offer a fast, non-drug option to ease severe depression and suicidal thoughts in young people.
What could go wrong: This is a very small early study (25 people) with no placebo group, so results may not apply widely. The treatment is intense (10 sessions daily for 5 days) and may not work for everyone.

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Conditions

The condition(s) this trial relates to.

major depressive disorder Suicidal Ideation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSIVE DISORDER (MDD) SUICIDAL IDEATION

Contacts and locations

Locations

UC Davis Medical Center
RECRUITING

Sacramento, California, 95817, United States

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