HEALTHY

This study tested a new cooling device designed to reduce pain during radio-frequency microneedling, a cosmetic skin treatment. Six healthy women participated to see how well the device cooled the skin and eased discomfort. The study was terminated early, so results are limited.

This small pilot study tested whether a cream containing stem cell secretome and licorice root extract could safely improve vaginal laxity (looseness) in women aged 40 to 55 in Malaysia. Over 5 weeks, researchers measured changes in vaginal tightness using a questionnaire and a p…

This early-stage study aimed to test the safety of a new drug called LY3872386 in healthy volunteers and people with atopic dermatitis (eczema). The study was terminated early, so no meaningful results are available. Only 18 participants were planned, and the drug's effects on ec…

This early-stage study looked at how healthy men absorb, break down, and eliminate the experimental drug BI 1839100. Eight participants were planned to receive the drug by mouth and by vein to measure how much reaches the bloodstream and how it leaves the body. The trial was stop…

This early-stage study tested whether a new medicine called REM0045392, being developed for Alzheimer's disease, is safe and tolerable in healthy people. It involved 19 healthy men and older adults who took either the medicine or a placebo, with doses increased over time. The stu…

This study tested a drug called ciraparantag to see if it could quickly reverse the effects of blood thinners in healthy adults. The trial was stopped early and involved 41 participants. The main goal was to measure how well the drug worked using a special blood clotting test.

This early-stage study tested a single dose of the experimental drug BI 1569912 in 68 healthy men to see if it is safe and how the body absorbs and processes it. The study also looked at whether food changes drug absorption. The trial was terminated early, and it was not designed…

This early-stage study tested an experimental drug called PF-07314470 in healthy adults to see if it was safe and how the body processes it. The study was terminated early, and no results are available. It involved 23 participants and was run by Pfizer.

This early-stage study tested the safety and how the body handles a new drug called MT-6345 in 52 healthy adults. Participants received either the drug or a placebo to check for side effects and measure drug levels in the blood. The study was stopped early, and it does not aim to…

This study tested a new, taste-masked powder form of the antibiotic delafloxacin in 16 healthy adults. The goal was to see if the body absorbs the powder as well as the current tablet. The study was stopped early, but the results help understand if the powder could be a good opti…

This study looked at how oxytocin, a natural hormone, affects pain from heat. Seven people (healthy volunteers and those with severe knee arthritis) received oxytocin through an IV. Researchers measured pain scores during a 5-minute heat test on the skin. The goal was to build a …

This early-stage study aimed to check the safety and how the body handles multiple doses of an experimental drug called BI 3731579. It involved 30 healthy volunteers aged 18 to 55 who took the drug or a placebo for 15 days. The study was terminated, so results are limited.

This study looked at how a standardized ashwagandha (Withania somnifera) supplement is absorbed in healthy adults aged 65 and older. Researchers gave 11 participants either 240 or 480 mg of the supplement and measured levels of active compounds in their blood over 48 hours. The g…

This study looked at how safe an experimental drug called BI 706321 is and how the body processes it. It involved 48 healthy Japanese and Chinese men who took either the drug or a placebo. The trial was stopped early, and the main goal was to check for side effects.

This study looked at how changing when you eat affects blood sugar, body temperature, and sleep in people with prediabetes, type 2 diabetes, and healthy adults. Researchers used wearable devices to track glucose and sleep patterns. The goal was to understand if meal timing alone …

This study tested a new type of MRI that uses xenon gas instead of X-rays to take pictures of the lungs and brain. Healthy adults aged 18 to 75 inhaled the gas and then had scans to see if the images were as good as or better than standard MRIs. The goal was to improve the techno…

This early-stage study tested an experimental oral medicine (PF-07899895) in healthy adults aged 18–65 to check its safety and how the body processes it. Participants received either the drug or a placebo in different dosing schedules over several weeks. The trial was terminated …

This study looks at how healthy men absorb, break down, and eliminate a drug called BI 1819479. It has two parts: one tracks the drug's radioactivity in urine and stool, and the other compares a tablet form to a low-dose injection. The goal is to understand the drug's behavior in…

This early-stage study aimed to check the safety and side effects of a new drug called LY3463251 in healthy and overweight adults. Participants received either the drug or a placebo under the skin. The study was stopped early, and no results are available.

This early study aimed to see if insulin given as a nasal spray can reach the brain and spinal fluid. Only 2 healthy adults took part before the study was stopped. Researchers collected fluid samples before and after a single dose to measure insulin levels. The results will help …

This study aimed to see if a mind-body medicine training program could help parole staff feel less stressed, anxious, and burned out, while increasing their resilience and empathy. Twenty-seven staff members attended a 4-day training, a 2-day practicum, and group sessions, and fi…

This study looked at how moderate versus high intensity exercise programs affect the way healthy, sedentary adults process pain. Researchers measured pain sensitivity and the body's natural pain control systems. The goal was to find the best exercise prescription for reducing pai…

This study looked at why exercise training improves blood vessel function less in some people with COPD compared to healthy individuals. Researchers measured blood vessel health and related biological markers in 69 participants (COPD patients and healthy volunteers) before and af…

This study looked at how running a marathon on flat roads compares to running a trail race with hills and uneven ground. Researchers measured muscle strength in the legs before and after each race to see which type causes more fatigue and how quickly runners recover. The goal was…

This study tested whether a gel made with tiny silver particles could kill bacteria on hands better than a common alcohol-based hand gel. Healthy adults had their hands covered with a harmless bacteria, then used one of the gels. The study was stopped early and only 22 people too…

This study aimed to see how two malaria medications, artemether-lumefantrine and amodiaquine, interact in healthy adults. It enrolled 8 healthy Thai volunteers and measured drug levels in the blood. The study was terminated early, so results are limited. It does not offer any tre…

This early-stage study aimed to check the safety and how the body handles a new experimental drug called BI 3009947 in healthy men. It also compared two different pill versions of the drug and looked at how food affects one of them. The study was stopped early and involved 40 par…

This study aimed to compare how the immune system responds to two different seasonal flu vaccines, one with an adjuvant (Fluad) and one without (Afluria), in healthy adults aged 18-49 who hadn't had a flu shot in at least three years. Only 2 people enrolled before the study was t…

This study aimed to check the safety and side effects of an experimental drug called LY3526318 in healthy adults. It was a Phase 1 trial with two parts, lasting up to 51 days total. The study was terminated early, and no results are available. It involved 76 healthy participants …