HEALTHY

This study is testing a new HPV vaccine called V540A. It aims to protect against more types of the HPV virus than the current standard vaccine, potentially preventing more cancers. Researchers will compare the safety and immune response of the new vaccine to the existing one in 5…

This study aims to see if eating walnuts daily for six months can improve blood flow and insulin sensitivity in the brain for adults with abdominal obesity. Researchers will measure changes in brain function, thinking skills, and appetite control using MRI scans and cognitive tes…

This is the first study in humans to test the safety and side effects of a new drug called XmAb657. It will involve both healthy volunteers and people with idiopathic inflammatory myopathy, a group of rare autoimmune diseases that cause muscle inflammation and weakness. Participa…

This study aims to see if taking low-dose aspirin at a specific time of day can prevent a common pain reliever (celecoxib) from raising blood pressure. It will involve 60 healthy adults who are known to have their blood pressure go up when taking celecoxib. Researchers will test …

This study aims to see if a weekly pill called everolimus, strength training, or both can help improve bone and muscle health in women aged 60-75 who have low bone density. Researchers will compare these approaches to a control group that does not receive the active treatment. Th…

This study is testing a device called Inflammacheck that analyzes chemicals in a person's breath. Researchers want to see if these breath patterns can help doctors tell the difference between lung cancer and other common lung problems like pneumonia or asthma. They will collect b…

This study is testing a new foot scanner that uses artificial intelligence (AI) to measure how pressure is distributed across the bottom of your feet. Researchers will compare the scanner's readings to a current gold-standard machine to see if it's accurate and reliable. The goal…

This study is testing a new, more sensitive type of eye scanner. The goal is to see if it can detect the earliest signs of glaucoma by measuring specific light properties in the retina. The study will enroll 20 healthy volunteers to see if the scanner produces clear, high-quality…

This study is testing a new portable device designed to measure how loose or 'wobbly' an ankle joint is. Researchers want to see if the device gives accurate and consistent readings in healthy people, those who have recovered from a sprain, and those with ongoing ankle instabilit…

This study is testing a culturally-centered education program designed to prevent substance use and promote mental and sexual health among American Indian youth. Over 800 youth, parents, and school staff on the Fort Peck Reservation will participate in workshops and teachings tha…

This study is testing whether a powder made from broccoli can help muscles recover faster after hard exercise. Fifteen healthy volunteers who don't normally lift weights will take either the broccoli powder or a placebo for a week, do a specific arm workout, and continue taking t…

This study is testing a plant-based supplement made from plum extract to see if it can help men with symptoms of a common, non-cancerous prostate enlargement. 38 men aged 40-60 will take either the supplement or a placebo pill daily for 8 weeks. Researchers will measure changes i…

This study is testing a cosmetic product to see if it helps skin heal better after a laser treatment. Researchers will apply the product to small areas on the forearms of 24 healthy adults with darker skin tones and compare it to untreated areas. They will measure how quickly wou…

This study aims to see if starting a structured physical therapy program soon after cosmetic leg lengthening surgery helps people move better, walk easier, and become more independent during recovery. It will follow 54 healthy adults aged 18-45 who have the surgery, tracking thei…

This study aims to see if a small vibration device can make dental injections less painful and scary for children. Kids aged 6-14 will try both the device and a dentist's hand vibration during their shots to see which works better. Researchers will measure the children's pain, an…

This study aims to see if adding fun, non-traditional sports like ultimate frisbee and flag football to physical education classes can help children become more physically fit, improve their coordination, and enjoy being active more. Researchers will work with about 210 healthy p…

This study aims to find out which type of activity best helps first-year university students improve their focus and manage stress. Researchers will compare three 12-week programs: high-intensity exercise combined with mental tasks, low-intensity Tai Chi, and supervised brain-tra…

This is a very early study to check if a new drug called KR23343 is safe for people and how the body handles it. It will involve 92 healthy adults. Researchers will give different single and repeated doses to see how much of the drug gets into the blood and if taking it with food…

This study is testing if a simple video camera (like a webcam) can accurately measure how people's movements become smaller and less exaggerated when they repeat an exercise many times. Researchers will record 22-26 healthy volunteers doing six different large movements. The goal…

This early-stage study aims to understand how a new medicine, BI 3000202, is processed by the body in people with and without liver problems. It will enroll 44 adults, including healthy volunteers and people with varying degrees of liver impairment. Each participant takes a singl…

This study aims to understand if the way encouragement is given affects how people feel pain. Healthy volunteers will receive heat pain and different types of suggestions. Researchers will measure pain ratings, expectations, and physical responses to see if matching the suggestio…

This study aims to understand how different types of laser therapy might temporarily affect nerve function in healthy people. Researchers will recruit 58 healthy adults aged 18-30 and randomly assign them to receive either high-power laser, low-power laser, or a fake (sham) laser…

This study aims to measure how much of a curcumin supplement gets into the bloodstream after people take it with food. It will compare a new capsule formula to an existing one in 12 healthy adults. The main goal is to see if the new product is absorbed differently, and researcher…

This study aims to translate and test a survey designed to understand the thoughts and feelings that influence whether women get screened for cervical cancer. Researchers will work with 215 healthy Turkish women to see if the translated questionnaire is reliable and valid for the…

This is an early safety study to see how a new drug called DA-1229_01 is absorbed and processed by the body when taken with food. It will involve 36 healthy volunteers. The main goal is to measure the drug levels in the blood and check for any side effects.

This study aims to see if a job rotation program helps heart care nurses. It will compare nurses who switch between different units every two months with those who stay in their usual roles. Researchers want to know if rotating improves nurses' skills, reduces burnout, and create…

This study aims to compare how two similar drugs are processed by the body and check their safety. It will enroll 60 healthy adults who will take each drug once in a specific order. The main goal is to understand how the body absorbs and handles these two versions of a medication…

This study aims to understand inflammation inside painful teeth by comparing people with toothaches to healthy individuals. Researchers will measure inflammation markers in saliva, gum fluid, and tooth samples to see if simple mouth tests can detect dental problems. The goal is t…

This study aims to understand if a new, more comfortable type of brain stimulation using magnetic fields can improve working memory better than an older electrical method. Researchers will test 102 healthy adults by having them perform memory tasks while their brain activity is m…

This study aims to check if taking a daily probiotic capsule for 15 days causes any stomach problems or other unwanted side effects in healthy people. It will involve 20 healthy adults who will take the probiotic and report how they feel. The main goal is to gather safety informa…

This study aims to find the best way to collect stool samples for analyzing gut bacteria. Researchers will compare different collection methods used in research against the current standard. The goal is to improve the accuracy and reliability of gut microbiome testing in future s…

This study aims to understand how a new technology called focused ultrasound affects the brain in healthy people. Researchers will use sound waves to gently stimulate a specific brain area and measure changes in brain signals and chemicals. The goal is to learn how this tool work…

This study aims to understand if the size and shape of a person's arms and hands are related to how well they can perform tasks with their hands and how quickly they react. Researchers will measure 46 healthy young adults and have them complete simple skill and reaction tests. Th…

This study aims to check how reliable a special camera is for measuring the smallest blood vessels under the tongue. Researchers will test the camera on both healthy volunteers and critically ill patients in the ICU to see if it gives consistent results. The goal is to validate t…

This study aims to understand if a 16-week exercise program can improve physical fitness and change the types of bacteria in the gut of healthy children. About 113 kids aged 7-10 will be randomly assigned to either do the exercise program or participate in quiet activities like r…

This study aims to see if a new tablet form of the drug tafamidis gets into the bloodstream the same way as the currently available capsule. It will involve 24 healthy adult volunteers who will take both forms after eating a meal. The main goal is to check if the two forms are eq…

This study is testing a new AI chatbot tool designed to help parents in the UK recognize misleading information about childhood vaccines. Researchers want to see if having a short, interactive conversation with the chatbot is better than just reading a fact sheet at improving par…

This study is testing whether a virtual reality (VR) training program is a practical way to teach nursing students how to better counsel patients having day surgery. It will involve 60 nursing students, with half trying the VR program and half receiving standard training. The mai…

This study aims to understand if wearing special glasses that emit bright light for 20 minutes can improve college students' attention, mood, and energy levels in the classroom. Researchers will compare students wearing two types of light glasses to students wearing no glasses. T…

This study aims to understand how carbamazepine, a common epilepsy medication, affects how the body processes an experimental cancer drug called mirdametinib. Researchers will give both drugs to 36 healthy volunteers and measure the drug levels in their blood over time. The goal …

This study aims to find the best way to give oxygen to people before they need a breathing tube placed for surgery. Researchers will compare two techniques in 30 healthy volunteers to see which one more effectively fills the body's oxygen reserves. The goal is to gather informati…

This study aims to see if using artificial intelligence (AI) tools during case discussions helps midwifery students learn. Researchers want to know if this AI-assisted training improves students' comfort with using AI, their skill level with the technology, and their overall clin…

This study aims to understand if providing free, healthy school meals improves children's health, well-being, and learning. It will follow about 3,200 Danish schoolchildren aged 10-15 for 1.5 years, comparing those who receive free meals with those who do not. Researchers will me…

This study aims to understand the links between lifestyle, heart health, and mental well-being in adults aged 40-65. It will recruit 1000 participants across four European regions to observe their habits and test the impact of a 3-month walking program. The goal is to gather data…

This study aims to better understand why blood sugar is high in type 2 diabetes by measuring how the liver makes new sugar from fat and other molecules. Researchers will compare this process in healthy, obese, and diabetic adults using special tracer infusions and blood tests. Th…

This study is testing whether a gamified phone app that uses AI can help young adults, especially those struggling to afford food, make healthier dietary choices. About 114 UC Davis students will use either the full app or a basic version for six weeks to track their eating. The …

This early study aims to understand if taking a new combination pill for diabetes with or without food changes how the body absorbs it. It will involve 28 healthy volunteers who will take the pill once while fasting and once after a meal. Researchers will measure drug levels in t…

This study aims to understand how our bodies regulate thirst. Researchers want to see if drinking a specific amount of plain water every day for four weeks can change a person's thirst signals and certain body chemistry markers. They will recruit 120 healthy young adults in Austr…

This early-stage study aims to compare how the body processes an experimental drug called mirikizumab when given as one injection versus two injections under the skin. It will involve 450 healthy volunteers to check the safety and how the drug moves through the body. The main goa…

This study aims to see if a product called Phaseolean® affects how the body's blood sugar responds to a high-carbohydrate meal. It will involve 12 healthy adults who will eat test meals on different days. The main goal is to measure changes in blood sugar and feelings of fullness…

This study aims to see if a special training program helps nursing students adjust to their first real hospital experience. Researchers will compare a new program using videos and peer mentors to the usual training. They will measure how stressed and well-adjusted the students fe…

This is a very early study to see if a new injection called HS-20136-2 is safe for people. It will be given once to about 38 healthy adults to check for side effects and see how the body handles it. The main goal is to gather basic safety information before testing it in people w…

This is an early-stage study to check the safety and how the body processes a new drug called BI 3814916. It involves 136 healthy volunteers who will receive either the drug or a placebo. The main goal is to see how well people tolerate it and to measure the drug levels in their …

This early-stage study aims to understand how the body absorbs and processes different tablet versions of the experimental drug enlicitide (MK-0616). It will involve 30 healthy adult volunteers who will take the drug so researchers can measure its levels in the blood over time. T…

This study aims to understand how eating different forms of chickpeas—like whole beans, hummus (puree), or chickpea-flour pasta—affects how your body burns fat and carbs for energy. Researchers will compare these diets to standard healthy eating guidelines in 204 healthy adults o…

This study aims to test a new, advanced ultrasound machine called the T5 system. Researchers want to see if it can create detailed, real-time moving images of the head, neck, and airway, which current ultrasound technology struggles to do. They will enroll 100 healthy volunteers …

This study aims to understand if the body's natural daily rhythm of the stress hormone cortisol is also present in the fluid surrounding eggs in the ovaries. Researchers will compare cortisol levels in blood and ovarian fluid collected from 20 women undergoing IVF treatment at 8 …

This is a small, early study to see how a new probiotic supplement affects the lining of the small intestine in healthy volunteers. Eight participants will take the probiotic (with and without a fiber) and a placebo on separate visits. Researchers will collect small tissue sample…

This is an early safety study to test a new medicine called PF-08065010, which is being developed for rheumatoid arthritis and lupus. The study will involve 100 healthy adults who will receive either the study medicine or a placebo injection or infusion. Researchers will monitor …

This early-stage study aims to understand how the body absorbs and processes a new tablet form of a drug called Aramchol. It will involve 32 healthy volunteers who will take single doses of the new tablet. Researchers will measure the drug levels in participants' blood over time …

This study aims to understand why people's moods, behaviors, and brains react differently to the same recreational drugs, like cannabis. Researchers will use brain scans and surveys to measure how young adults learn from rewards and anticipate them. The goal is to gather knowledg…