Can two factories make the same Parkinson's drug? a trial puts it to the test

NCT ID NCT07727785

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial investigates whether pramipexole tablets produced at two different manufacturing sites are processed identically by the body. Healthy volunteers aged 18 to 55 take both versions in a crossover design, and researchers compare drug levels in the blood. The goal is to confirm bioequivalence, which could ensure consistent medication quality regardless of where the drug is made.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
pramipexole tablets (Sifrol® and Mirapex®)
What this could lead to
If the tablets are bioequivalent, it could confirm that manufacturing at either site produces the same medicine, supporting reliable supply.
What could go wrong
This is a small, early-phase study in healthy people, not patients. Results may not reflect real-world use or detect rare differences.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Humanpharmakologisches Zentrum Biberach

    Biberach, 88397, Germany

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