Scientists decode hidden color secret for whiter teeth
NCT ID NCT07560761
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will test a combined tooth-whitening procedure on 10 healthy adults to see how the green-red color axis (called a*) contributes to overall whiteness. Participants will first get in-office bleaching with 40% hydrogen peroxide, then use a 16% carbamide peroxide gel at home for up to 12 weeks. The goal is to better understand what makes teeth look whiter, not to cure any disease.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Combined dental bleaching (in-office 40% hydrogen peroxide and at-home 16% carbamide peroxide)
- What this could lead to
- If successful, this could help dentists predict and improve tooth whitening results by understanding the role of the green-red color axis.
- What could go wrong
- This is a very small, early study with only 10 participants and no comparison group. Results may not apply to everyone, and bleaching can cause tooth sensitivity or gum irritation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 10 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria * Age 18 to 65 years * Good oral health * Presence of natural anterior teeth (incisors, canines, premolars) * Anterior teeth without restorations * Indication for tooth bleaching treatment * Ability to comply with study procedures and visits Exclusion Criteria * Smoking * Previous tooth bleaching treatment * Pregnancy * Breastfeeding * Restorations in anterior teeth * Presence of diseases affecting tooth color * Conditions that may interfere with study outcomes
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Valencia
Valencia, Valencia, 46010, Spain
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