Saliva test could spot tooth nerve inflammation

NCT ID NCT07450235

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at inflammation inside the tooth's inner tissue (dental pulp) in people with painful pulpitis compared to healthy individuals. Researchers will measure specific inflammation markers in saliva, gum fluid, and pulp tissue to see if they reflect the level of inflammation. The goal is to find out if simple saliva or oral fluid tests could one day help diagnose and monitor pulp inflammation without invasive procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to simple, non-invasive saliva tests to detect and monitor tooth pulp inflammation.

What could go wrong

This is an early observational study with only 50 participants, so results may not apply broadly. It does not test any treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Nantes University Hospital Dental Clinic

    Nantes, Loire-Atlantique, 44 000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••