Saliva test could spot tooth nerve inflammation
NCT ID NCT07450235
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at inflammation inside the tooth's inner tissue (dental pulp) in people with painful pulpitis compared to healthy individuals. Researchers will measure specific inflammation markers in saliva, gum fluid, and pulp tissue to see if they reflect the level of inflammation. The goal is to find out if simple saliva or oral fluid tests could one day help diagnose and monitor pulp inflammation without invasive procedures.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to simple, non-invasive saliva tests to detect and monitor tooth pulp inflammation.
- What could go wrong
- This is an early observational study with only 50 participants, so results may not apply broadly. It does not test any treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Nantes University Hospital Dental Clinic
Nantes, Loire-Atlantique, 44 000, France
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